dntt
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  • Official Full Name
  • deoxynucleotidyltransferase, terminal
  • Background
  • DNA nucleotidylexotransferase (DNTT) belongs to the DNA polymerase type-X family. DNTT catalyzes the addition of deoxynucleotides to the 3-hydroxyl terminus of oligonucleotide primers.
  • Synonyms
  • DNTT; deoxynucleotidyltransferase, terminal; DNA nucleotidylexotransferase; TDT; Terminal deoxynucleotidyltransferase; terminal transferase; terminal addition enzyme; terminal deoxyribonucleotidyltransferase; nucleosi
Cat.#:DNTT-2569HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNTT Protein, His-tagged
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Cat.#:DNTT-2797HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human DNTT Protein, GST-tagged
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Cat.#:DNTT-563HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Deoxynucleotidyltransferase, Terminal
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Cat.#:DNTT-318HTag:GST/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human DNTT Protein, GST-His-tagged
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Cat.#:DNTT-4745MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse DNTT Protein
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Cat.#:DNTT-1308RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey DNTT Protein, His-tagged
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Cat.#:DNTT-01BTag:
Source (Host):E. coliSpecies:Bovine
Product nameRecombinant Bovine DNTT Protein
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Cat.#:DNTT-6941CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken DNTT
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Cat.#:DNTT-2287ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish DNTT
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Cat.#:DNTT-6850HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human DNTT 293 Cell Lysate
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Involved Pathway

DNTT involved in several pathways and played different roles in them. We selected most pathways DNTT participated on our site, such as Hematopoietic cell lineage, Non-homologous end-joining, Validated targets of C-MYC transcriptional repression, which may be useful for your reference. Also, other proteins which involved in the same pathway with DNTT were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Hematopoietic cell lineage
CSF3R; CD3E; CD3D; IL7R; IL6R; CD8B; ITGA5; CR1; ITGA4; IL5; MME
Non-homologous end-joining
XRCC4; NHEJ1; DNTT; XRCC5; POLM; LIG4; XRCC6; POLL; PRKDC; DCLRE1C
Validated targets of C-MYC transcriptional repression
S100A7; CSDE1; ZFP36L1; SFXN3; GFI1; MXD4; LGALS1; NDRG1; TMEFF2; CLU

Protein Function

DNTT has several biochemical functions, for example, DNA binding, DNA nucleotidylexotransferase activity, DNA-directed DNA polymerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by DNTT itself. We selected most functions DNTT had, and list some proteins which have the same functions with DNTT. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein H2AFJ; ZNF501; ZBTB9; MBD3A; NEUROD6; HIST1H2BH; SP6; ZNF221; TFDP1A; TAF15
Function DNA nucleotidylexotransferase activity
Related Protein DNTT
Function DNA-directed DNA polymerase activity
Related Protein POLB; POLA1; POLD1; POLH; POLA2; CHRAC1; CCDC111; POLE3; POLL; POLM
Function metal ion binding
Related Protein HIVEP2A; ECE2; IRGF4; ZNF404; RTCB; ACVR2A; ESR2A; RREB1; B3GNT1; ZNF576.2
Function protein binding
Related Protein NR1D1; FAM54B; GLA; SIM1; DPEP1; CTNNAL1; APPL2; NHP2L1; GPI1; GDF7

Interacting Protein

DNTT has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with DNTT here. Most of them are supplied by our site. Hope this information will be useful for your research of DNTT.
REL; APOA1