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E2F2

  • Official Full Name

    E2F transcription factor 2

  • Overview

    E2F transcription factors are functionally regulated by binding to Rb p110, p107, and p130. E2F-2 is regulated by complex formation with Rb p110. E2F family members bind DNA as heterodimers with members of the DP family of polypeptides.
  • Synonyms

    E2F2; E2F transcription factor 2; transcription factor E2F2; E2F 2; E2F-2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human E2F2-27376TH Recombinant Human E2F2 Wheat Germ N/A 83 amino acids
Human E2F2-3004H Recombinant Human E2F2 Protein, GST-tagged Wheat Germ GST
Human E2F2-520HCL Recombinant Human E2F2 cell lysate N/A
Human E2F2-1635H Recombinant Human E2F2 protein, His & GST-tagged E.coli His/GST Arg129~Tyr429 (Accession # Q14209)
Human E2F2-133HF Recombinant Full Length Human E2F2 Protein In Vitro Cell Free System 83 amino acids
Human E2F2-2017H Recombinant Human E2F2 Protein (Arg129-Tyr429), N-His tagged E.coli N-His Arg129-Tyr429
Human E2F2-4111HF Recombinant Full Length Human E2F2 Protein, GST-tagged In Vitro Cell Free System GST 83 amino acids
Mouse E2F2-4931M Recombinant Mouse E2F2 Protein Mammalian Cell His
Mouse E2F2-2595M-B Recombinant Mouse E2F2 Protein Pre-coupled Magnetic Beads HEK293
Mouse E2F2-2595M Recombinant Mouse E2F2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • E2F2 Related Articles
  • E2F2 Related Research Area

E2F2 involved in several pathways and played different roles in them. We selected most pathways E2F2 participated on our site, such as Assembly of the pre-replicative complex, Association of licensing factors with the pre-replicative complex, Bladder cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with E2F2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Assembly of the pre-replicative complexE2F2;E2F1;CDT1;MCM8;E2F3;GMNN
Association of licensing factors with the pre-replicative complexE2F2;GMNN;E2F1;CDT1;E2F3
Bladder cancerMMP1;CCND1;HRAS;KRAS;ARAF;CXCL8;DAPK2;MYC;DAPK3
CDC6 association with the ORC:origin complexMCM8;E2F2;E2F3
Cell CycleSMAD3;SGOL1;CDC25C;ESCO1;YWHABA;DCTN1;ORC2L;SDCCAG8;CDC20
Cell Cycle, MitoticDYNC1H1;CEP72;DBF4;E2F3;ARPP19A;GOLGA2;DSN1;MAPRE1B;CEP78
Cellular SenescenceIGFBP7;RBB4L;KAT5;AGO3;SUZ12A;PHC2;MAPKAPK2B;TNIK;SUZ12

E2F2 has several biochemical functions, for example, DNA binding, core promoter binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by E2F2 itself. We selected most functions E2F2 had, and list some proteins which have the same functions with E2F2. You can find most of the proteins on our site.

Function Related Protein
DNA bindingTOPBP1;RAG1;RPAP1;HIST3H3;NR4A2A;ZNF385A;FOXL1;EP300;HIST1H2BF
core promoter bindingARNTL;SAFB;XBP1;NKX3;TFAP2C;E2F3;RB1;E2F1;CLOCK
protein bindingIL10RB;GMNN;EIF4E2;BMP1A;RTN2;Fgf15;CCDC13;C4orf33;INCA1
transcription factor activity, sequence-specific DNA bindingTCF7L2;NFE2L2B;HOXC6;CNOT8;L3MBTL4;EGR2B;ZFP35;SOX13;ZFP42
transcription factor bindingPAXBP1;BCL3;JUNBA;ZFPM1;HEY1;FOXA2;PPARG;PIK3R1;LEF1

E2F2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with E2F2 here. Most of them are supplied by our site. Hope this information will be useful for your research of E2F2.

RB1; Sp1; E7; E2F1; MCPH1; GNB5; BCAR1; GIT2; q81sn0_bacan; Cep152

Chafin, CB; Regna, NL; et al. MicroRNA-let-7a promotes E2F-mediated cell proliferation and NF kappa B activation in vitro. CELLULAR & MOLECULAR IMMUNOLOGY 11:79-93(2014).
Bucasas, KL; Franco, LM; et al. Early Patterns of Gene Expression Correlate With the Humoral Immune Response to Influenza Vaccination in Humans. JOURNAL OF INFECTIOUS DISEASES 203:921-929(2011).
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