e2f2
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  • Official Full Name
  • E2F transcription factor 2
  • Background
  • E2F transcription factors are functionally regulated by binding to Rb p110, p107, and p130. E2F-2 is regulated by complex formation with Rb p110. E2F family members bind DNA as heterodimers with members of the DP family of polypeptides.
  • Synonyms
  • E2F2; E2F transcription factor 2; transcription factor E2F2; E2F 2; E2F-2
Cat.#:E2F2-3004HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human E2F2 Protein, GST-tagged
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Cat.#:E2F2-1635HTag:His|GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human E2F2 protein, His & GST-tagged
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Cat.#:E2F2-27376THTag:N/A
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human E2F2
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Cat.#:E2F2-4931MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse E2F2 Protein
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Cat.#:E2F2-520HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human E2F2 cell lysate
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Involved Pathway

E2F2 involved in several pathways and played different roles in them. We selected most pathways E2F2 participated on our site, such as Assembly of the pre-replicative complex, Association of licensing factors with the pre-replicative complex, Bladder cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with E2F2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Assembly of the pre-replicative complex
E2F1; MCM8; E2F2; CDT1; E2F3; GMNN
Association of licensing factors with the pre-replicative complex
CDT1; E2F3; GMNN; E2F2; E2F1
Bladder cancer
TYMP; CDKN2A; MMP9; RB1; EGF; TP53; E2F1; E2F2; MAPK1; DAPK3
CDC6 association with the ORC:origin complex
MCM8; E2F2; E2F3
Cell Cycle
DSN1; RBL2; AURKB; CLIP1; MAPRE1; NDE1; CENPK; RBBP8; MCM6L; BABAM1
Cell Cycle, Mitotic
CNEP1R1; MASTL; ENSA; SGOL1; KIF2C; CKS1B; CP110; ESCO1; NUP35; H3F3D
Cellular Senescence
H3F3B.1; CABIN1; HMGA1B; HIST1H1A; PHC2; CDKN2D; TERF2; EHMT2; RBB4L; CBX8B

Protein Function

E2F2 has several biochemical functions, for example, DNA binding, core promoter binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by E2F2 itself. We selected most functions E2F2 had, and list some proteins which have the same functions with E2F2. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ZNF410; SP1; POU5F1; KIN; GM14479; RUNX1T1; NKX2-5; ISX; EEF1D; SP9
Function core promoter binding
Related Protein NOTCH1; MED1; NPAS2; DHX36; SFPI1; NKX3-1; IRF9; E2F8; E2F2; HNRNPU
Function protein binding
Related Protein RUSC2; FASTKD5; ARL2BP; PRKG1; DCTN3; TDRD9; RILP; CX3CR1; SOX7; TBX6
Function transcription factor activity, sequence-specific DNA binding
Related Protein TEFB; ZNF133; RBPJ; ZFP516; EGR2; TBX10; TGIF1; PTF1A; MSC; TFDP2
Function transcription factor binding
Related Protein PDX1; SOX10; SOST; NKX2; PPRC1; CTNNB1; VDRA; GCM1; PAX6; FIGLA

Interacting Protein

E2F2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with E2F2 here. Most of them are supplied by our site. Hope this information will be useful for your research of E2F2.
RB1; Sp1; E7; E2F1; MCPH1; GNB5; BCAR1; GIT2; q81sn0_bacan; Cep152

E2F2 Related Articles

Chafin, CB; Regna, NL; et al. MicroRNA-let-7a promotes E2F-mediated cell proliferation and NF kappa B activation in vitro. CELLULAR & MOLECULAR IMMUNOLOGY 11:79-93(2014).
Bucasas, KL; Franco, LM; et al. Early Patterns of Gene Expression Correlate With the Humoral Immune Response to Influenza Vaccination in Humans. JOURNAL OF INFECTIOUS DISEASES 203:921-929(2011).