eif2a
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  • Official Full Name
  • eukaryotic translation initiation factor 2A, 65kDa
  • Background
  • EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al.,;2002 (PubMed 12133843)).
  • Synonyms
  • EIF2A; eukaryotic translation initiation factor 2A, 65kDa; eukaryotic translation initiation factor 2A; EIF 2A; 65 kDa eukaryotic translation initiation factor 2A; CDA02; EIF-2A; MST089; MSTP004; MSTP089
Cat.#:EIF2A-3145HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human EIF2A Protein, GST-tagged
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Cat.#:EIF2A-338HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human EIF2A Protein, MYC/DDK-tagged
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Cat.#:EIF2A-30HTag:N/A
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human EIF2A
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Cat.#:EIF2A-12348HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EIF2A, GST-tagged
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Cat.#:EIF2A-18HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EIF2A protein, His-tagged
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Cat.#:EIF2A-28490THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human EIF2A, His-tagged
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Cat.#:EIF2A-5074MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse EIF2A Protein
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Cat.#:EIF2A-2977CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken EIF2A
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Cat.#:EIF2A-3075ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish EIF2A
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Cat.#:EIF2A-6675HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human EIF2A 293 Cell Lysate
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Involved Pathway

EIF2A involved in several pathways and played different roles in them. We selected most pathways EIF2A participated on our site, such as IL-6 Signaling Pathway, TGF-beta receptor signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
IL-6 Signaling Pathway
BMX; EIF2A; CDK5R1B; DAXX
TGF-beta receptor signaling
DAB2; STRAP; EIF2A; TGFBR3

Protein Function

EIF2A has several biochemical functions, for example, protein binding, ribosome binding, tRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF2A itself. We selected most functions EIF2A had, and list some proteins which have the same functions with EIF2A. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein ADA; SEC22A; POLR1A; TGOLN2; RAET1D; NUAK2; NDFIP1; KCNRG; ASF1A; RPL39L
Function ribosome binding
Related Protein EFTUD1; RICTOR; EIF2S1B; CPEB2; MTRF1L; EIF5A; SBDS; EIF2S1A; MTOR; EIF3K
Function tRNA binding
Related Protein CTU1; RPL35A; XPOT; EARS2; AARSD1; IGHMBP2; ALKBH8; TRMU; CARS; IFIT5
Function translation initiation factor activity
Related Protein MTIF2; EIF1AXB; EIF3F; EIF3EB; EIF4E; EIF4G1; EIF1AY; COPS5; EIF5B; EIF4A1

Interacting Protein

EIF2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF2A here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF2A.
MLH1; q81z87_bacan; MAST3; ABL1; NEDD8; ESR2; UPF1

EIF2A Related Articles

Dametto, P; Lakkaraju, AKK; et al. Neurodegeneration and Unfolded-Protein Response in Mice Expressing a Membrane-Tethered Flexible Tail of PrP. PLOS ONE 10:-(2015).
Wu, CX; Wang, SJ; et al. The Z alpha domain of PKZ from Carassius auratus can bind to d(GC)(n) in negative supercoils. FISH & SHELLFISH IMMUNOLOGY 28:783-788(2010).