EIF5A2 Protein, eukaryotic translation initiation factor 5A2

EIF5A2

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EIF5A2

Official Full Name eukaryotic translation initiation factor 5A2
Background Eukaryotic translation initiation factor 5A-2 is a protein that in humans is encoded by the EIF5A2 gene.
Synonyms EIF5A2; eukaryotic translation initiation factor 5A2; eukaryotic translation initiation factor 5A-2; eIF 5A 2; eIF 5A2; eIF5AII; Eukaryotic initiation factor 5A isoform 2; 9630038B20; eIF-4D; eIF-5A-2; eIF-5A2; EIF5A 2; IF5A2_HUMAN; MGC124092; MGC124093; OTTHUMP00000213742; OTTHUMP00000213744; OTTHUMP00000213745; eukaryotic initiation factor 5A
    • Species :
    • Chicken
    • Human
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human EIF5A2-12389H Recombinant Human EIF5A2, GST-tagged E.coli GST
    Human EIF5A2-238H Recombinant Human EIF5A2, His tagged E.coli Fc
    Human EIF5A2-27178TH Recombinant Human EIF5A2, His-tagged E.coli His
    Human EIF5A2-3215H Recombinant Human EIF5A2 Protein, GST-tagged Wheat Germ GST
    Human EIF5A2-6640HCL Recombinant Human EIF5A2 293 Cell Lysate HEK293 N/A
    Rhesus Macaque EIF5A2-1434R Recombinant Rhesus monkey EIF5A2 Protein, His-tagged Mammalian Cell His
    Chicken EIF5A2-7080C Recombinant Chicken EIF5A2 Mammalian Cell His
    Zebrafish EIF5A2-12459Z Recombinant Zebrafish EIF5A2 Mammalian Cell His

    EIF5A2 involved in several pathways and played different roles in them. We selected most pathways EIF5A2 participated on our site, such as Gamma carboxylation, hypusine formation and arylsulfatase activation, Hypusine synthesis from eIF5A-lysine, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF5A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Gamma carboxylation, hypusine formation and arylsulfatase activation PROZ; PROCA; DNAJC24; ARSE; ARSJ; DHPS; FURINA; FURINB; ATPBD4; DPH5
    Hypusine synthesis from eIF5A-lysine EIF5A2; DOHH; DHPS; EIF5A
    Metabolism of proteins INHA; APEH; ADAMTS8; ST6GAL2B; WDR85; SCFD1; PHC3; SAE1; TRAPPC10; B3GNT8
    Post-translational protein modification SPON1A; SUMF2; C8orf84; TMED10; ARSF; MUC4; TFG; B3GNT8; LMAN2; ALG2

    EIF5A2 has several biochemical functions, for example, protein binding, ribosome binding, translation elongation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF5A2 itself. We selected most functions EIF5A2 had, and list some proteins which have the same functions with EIF5A2. You can find most of the proteins on our site.

    Function Related Protein
    protein binding NOTCH2; IL17RE; HSPD1; BAX; TNFRSF10B; RFX4; TIMM23; FAM151B; H3F3A; KLHL2
    ribosome binding NARG1; SEC61B; CPEB4; EFTUD1; ETF1B; RPN2; EIF6; CPEB1B; WIBG; EIF5A
    translation elongation factor activity EEF1DA; EEFSEC; EEF1A1A; EEF1A1; TSFM; EEF1DB; EIF5A2; EIF5A; EEF2B; HBS1L

    EIF5A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF5A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF5A2.

    DHPS; SDCBP; REL; NIF3L1; CDC23; RAB30; PTBP2; NS; DCC

    Fujimura, K; Wright, T; et al. A Hypusine-eIF5A-PEAK1 Switch Regulates the Pathogenesis of Pancreatic Cancer. CANCER RESEARCH 74:6671-6681(2014).
    Tsang, FH; Au, V; et al. Prognostic Marker MicroRNA-125b Inhibits Tumorigenic Properties of Hepatocellular Carcinoma Cells Via Suppressing Tumorigenic Molecule eIF5A2. DIGESTIVE DISEASES AND SCIENCES 59:2477-2487(2014).

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