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EIF5A2

  • Official Full Name

    eukaryotic translation initiation factor 5A2

  • Overview

    Eukaryotic translation initiation factor 5A-2 is a protein that in humans is encoded by the EIF5A2 gene.
  • Synonyms

    EIF5A2; eukaryotic translation initiation factor 5A2; eukaryotic translation initiation factor 5A-2; eIF 5A 2; eIF 5A2; eIF5AII; Eukaryotic initiation factor 5A isoform 2; 9630038B20; eIF-4D; eIF-5A-2; eIF-5A2; EIF5A 2; IF5A2_HUMAN; MGC124092; MGC124093; OTTHUMP00000213742; OTTHUMP00000213744; OTTHUMP00000213745; eukaryotic initiation factor 5A;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • Fc
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human EIF5A2-12389H Recombinant Human EIF5A2, GST-tagged E.coli GST 1-153a.a.
Human EIF5A2-238H Recombinant Human EIF5A2, His tagged E.coli Fc
Human EIF5A2-27178TH Recombinant Human EIF5A2, His-tagged E.coli His 153 amino acids
Human EIF5A2-3215H Recombinant Human EIF5A2 Protein, GST-tagged Wheat Germ GST
Human EIF5A2-6640HCL Recombinant Human EIF5A2 293 Cell Lysate HEK293 N/A
Human EIF5A2-1278H Recombinant Human EIF5A2 protein, His-tagged E.coli His Met1-Lys153
Human EIF5A2-4318H Recombinant Human EIF5A2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human EIF5A2-3580H Recombinant Human EIF5A2 Protein (Met1-Lys153), N-His tagged E.coli N-His Met1-Lys153
Human EIF5A2-4301HF Recombinant Full Length Human EIF5A2 Protein, GST-tagged In Vitro Cell Free System GST 153 amino acids
Mouse Eif5a2-2793M Recombinant Mouse Eif5a2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque EIF5A2-1434R Recombinant Rhesus monkey EIF5A2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque EIF5A2-1258R-B Recombinant Rhesus Macaque EIF5A2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque EIF5A2-1258R Recombinant Rhesus Macaque EIF5A2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish EIF5A2-12459Z Recombinant Zebrafish EIF5A2 Mammalian Cell His
Chicken EIF5A2-7080C Recombinant Chicken EIF5A2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • EIF5A2 Related Articles

EIF5A2 involved in several pathways and played different roles in them. We selected most pathways EIF5A2 participated on our site, such as Gamma carboxylation, hypusine formation and arylsulfatase activation, Hypusine synthesis from eIF5A-lysine, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with EIF5A2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Gamma carboxylation, hypusine formation and arylsulfatase activationARSD;DPH1;ATPBD4;ARSJ;SUMF2;EEF2;F9A;F9B;ARSI
Hypusine synthesis from eIF5A-lysineEIF5A2;EIF5A;DHPS;DOHH
Metabolism of proteinsBET1;MUC20;SFTPB;F9B;RHBDL1;NAPAA;WDR85;ATP6AP2;ANKRD28
Post-translational protein modificationADAMTSL1;MIA3;ARSH;ADAMTS18;PPP6R3;ALG2;NAPG;ST6GALNAC1.2;EIF5A

EIF5A2 has several biochemical functions, for example, protein binding, ribosome binding, translation elongation factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EIF5A2 itself. We selected most functions EIF5A2 had, and list some proteins which have the same functions with EIF5A2. You can find most of the proteins on our site.

Function Related Protein
protein bindingDTNBP1;C3orf15;NAA38;FAM154A;SPHK1;RECQL;ATL1;LRP2;MED24
ribosome bindingEFTUD1;IGHMBP2;RPN2;ETF1;SBDS;ETF1A;RPSA;RICTOR;YTHDF1
translation elongation factor activityEEF1A1B;TSFM;GFM1;EEF1D;EEF1DB;EEF1A2;EEF1B2;EIF5A;EEF1G

EIF5A2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EIF5A2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EIF5A2.

DHPS; SDCBP; REL; NIF3L1; CDC23; RAB30; PTBP2; NS; DCC

Fujimura, K; Wright, T; et al. A Hypusine-eIF5A-PEAK1 Switch Regulates the Pathogenesis of Pancreatic Cancer. CANCER RESEARCH 74:6671-6681(2014).
Tsang, FH; Au, V; et al. Prognostic Marker MicroRNA-125b Inhibits Tumorigenic Properties of Hepatocellular Carcinoma Cells Via Suppressing Tumorigenic Molecule eIF5A2. DIGESTIVE DISEASES AND SCIENCES 59:2477-2487(2014).
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