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F2RL3

  • Official Full Name

    coagulation factor II (thrombin) receptor-like 3

  • Overview

    Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.
  • Synonyms

    F2RL3; coagulation factor II (thrombin) receptor-like 3; proteinase-activated receptor 4; PAR4; proteinase activated receptor 4; PAR-4; thrombin receptor-like 3; protease-activated receptor-4; proteinase-activated receptor-4; coagulation factor II recepto;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • MYC
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human F2RL3-3618H Recombinant Human F2RL3 Protein, GST-tagged Wheat Germ GST
Human F2RL3-6483HCL Recombinant Human F2RL3 293 Cell Lysate HEK293 N/A
Human F2RL3-3231H Recombinant Human F2RL3 Protein (Gly48-Gln385), N-GST tagged E.coli N-GST Gly48-Gln385
Human F2RL3-2752H Recombinant Human F2RL3 protein, His-tagged E.coli His 305-385 aa
Human F2RL3-29834H Active Recombinant Human CX3CR1 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Mouse F2RL3-5412M Recombinant Mouse F2RL3 Protein Mammalian Cell His
Mouse F2rl3-998M Recombinant Mouse F2rl3 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse F2RL3-2920M-B Recombinant Mouse F2RL3 Protein Pre-coupled Magnetic Beads HEK293
Mouse F2RL3-2920M Recombinant Mouse F2RL3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat F2RL3-2179R Recombinant Rat F2RL3 Protein Mammalian Cell His
Rat F2RL3-1836R Recombinant Rat F2RL3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat F2RL3-1836R-B Recombinant Rat F2RL3 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL6322HF Recombinant Full Length Human Proteinase-Activated Receptor 4(F2Rl3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (48-385)
Mus musculus (Mouse) RFL4159MF Recombinant Full Length Mouse Proteinase-Activated Receptor 4(F2Rl3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (60-396)
Rattus norvegicus (Rat) RFL13537RF Recombinant Full Length Rat Proteinase-Activated Receptor 4(F2Rl3) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (59-395)
Kit-0928 TR-FRET ERR alpha Coactivator Assay Kit, rabbit N/A
Kit-1236 F2RL3 (PAR4) CHO-K1 β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

F2RL3 involved in several pathways and played different roles in them. We selected most pathways F2RL3 participated on our site, such as Rap signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with F2RL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Rap signaling pathwayTLN1;TEK;ANGPT4;RASGRP3;PIK3R1;MAPK3;ANGPT1;LPAR4;PDGFRA
Neuroactive ligand-receptor interactionP2RX4A;TRHRB;C3AR1;GRIA3A;TAAR12E;BDKRB2;HTR2B;P2RX3A;TAAR14L
Platelet activationRHOA;FERMT3;PIK3CB;PRKG2;ACTG1;STIM1;BTK;Adcy4;ORAI1
Pathways in cancerGNG11;RARB;FGF10;MAPK3;GNG3;Pdgfa&Pdgfb;LAMB4;MET;BAD

F2RL3 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by F2RL3 itself. We selected most functions F2RL3 had, and list some proteins which have the same functions with F2RL3. You can find most of the proteins on our site.

Function Related Protein

F2RL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with F2RL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of F2RL3.

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