f2rl3
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  • Official Full Name
  • coagulation factor II (thrombin) receptor-like 3
  • Background
  • Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin.
  • Synonyms
  • F2RL3; coagulation factor II (thrombin) receptor-like 3; proteinase-activated receptor 4; PAR4; proteinase activated receptor 4; PAR-4; thrombin receptor-like 3; protease-activated receptor-4; proteinase-activated receptor-4; coagulation factor II recepto
Cat.#:F2RL3-3618HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human F2RL3 Protein, GST-tagged
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Cat.#:F2RL3-5412MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse F2RL3 Protein
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Cat.#:F2RL3-2179RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat F2RL3 Protein
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Cat.#:F2RL3-6483HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human F2RL3 293 Cell Lysate
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Cat.#:Kit-1236Tag:
Source (Host):Species:
Product nameF2RL3 (PAR4) CHO-K1 β-Arrestin GPCR Assay Kit
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Cat.#:Kit-0928Tag:
Source (Host):Species:
Product nameTR-FRET ERR alpha Coactivator Assay Kit, rabbit
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Involved Pathway

F2RL3 involved in several pathways and played different roles in them. We selected most pathways F2RL3 participated on our site, such as Rap signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation, which may be useful for your reference. Also, other proteins which involved in the same pathway with F2RL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Rap signaling pathway
PIK3CB; DOCK4; PIK3R1; GNAI1; FGF1; ITGB2L; FGF19; KLK1B4; ARAP3; SIPA1L2
Neuroactive ligand-receptor interaction
HRH4; S1PR5; GPR35; CHRM5B; DRD4-RS; GRPR; GHSR; HTR6; OXTR; GRM5
Platelet activation
PLA2G4C; MYLK3; LYN; PLCB4; GP6; MYLK4; ACTB; AKT1; PLCG2; PRKCZ
Pathways in cancer
TGFA; TPR; MTOR; NTRK1; FGF8; MDM2; CDC42; WNT2; PIK3CD; HDAC1