faf1
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  • Official Full Name
  • Fas (TNFRSF6) associated factor 1
  • Background
  • FAF1 (Fas-associated protein factor 1) specifically interacts with the cytoplasmic domain of wild type, but not mutated Fas in both yeast and mammalian cells. When transiently expressed in T cells, FAF1 potentiates Fas-induced apoptosis. In contrast to TR
  • Synonyms
  • FAF1; Fas (TNFRSF6) associated factor 1; FAS-associated factor 1; CGI 03; hFAF1; HFAF1s; TNFRSF6 associated factor 1; UBX domain protein 3A; UBXD12; UBXN3A; TNFRSF6-associated factor 1; UBX domain-containing protein 12; UBX domain-containing protein 3A; C
Cat.#:FAF1-3647HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FAF1 Protein, GST-tagged
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Cat.#:FAF1-5435MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FAF1 Protein
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Cat.#:FAF1-2195RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FAF1 Protein
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Cat.#:FAF1-1541RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FAF1 Protein, His-tagged
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Cat.#:FAF1-12221ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish FAF1
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Cat.#:FAF1-6470HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human FAF1 293 Cell Lysate
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Involved Pathway

FAF1 involved in several pathways and played different roles in them. We selected most pathways FAF1 participated on our site, such as FAS pathway and Stress induction of HSP regulation, RB in Cancer, TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FAF1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
FAS pathway and Stress induction of HSP regulation
DFFA; FAF1; LMNB2; DAXX
RB in Cancer
PRMT2; SMARCA2; TOP2A; RABIF; HMGB2; DCK; RBP1; FAF1; ANLN; HLTF
TNF-alpha/NF-kB Signaling Pathway
COPS3; SMARCE1; CAPN3; KIAA1967; UNC5CL; TRPC4AP; SMARCB1; RNF216; TNIP1; DCAF7

Protein Function

FAF1 has several biochemical functions, for example, NF-kappaB binding, heat shock protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FAF1 itself. We selected most functions FAF1 had, and list some proteins which have the same functions with FAF1. You can find most of the proteins on our site.
Function
Related Protein
Function NF-kappaB binding
Related Protein HDAC2; BCL10; CDKN2A; FAF1; NFKBIA; HSPA6; BRMS1; NPM1; TAF4B; NFKBID
Function heat shock protein binding
Related Protein NFKBIA; HSPA1L; DNAJA3B; GPR37; GM5506; DNAJA3; DNAJC9; SSUH2RS1; HDAC2; DNAJC7
Function protein binding
Related Protein KATNA1; CDC42EP5; SEMA4C; EEA1; FBP2; PICK1; WWTR1; GLE1; BCDIN3D; DHH
Function protein domain specific binding
Related Protein HIST1H4C; MYH9; RUNX2; SCN5A; CACNB2; NR0B1; MECP2; CNTLN; ST13; GABRR2
Function protein kinase binding
Related Protein CDK5R1; PEBP1; DCX; CALM3; TRAP1; SKAP1; JTB; C10orf46; FAM83B; PTPRC
Function protein kinase regulator activity
Related Protein RAC2; CSNK2B; FAF1; CDK5RAP1; KIDINS220; APC; CDC37; KIDINS220B; ANKRD54
Function ubiquitin binding
Related Protein VPS36; RNF31; UCHL3; CRY2; RNF168; TOM1L1; OTUB1; UBXN2A; UBXN11; IWS1
Function ubiquitin protein ligase binding
Related Protein YWHAE; BRCA1; C10orf46; CUL3; ZFP746; TSG101; TMEM173; DNAJA1; HSPA5; IKBKE

Interacting Protein

FAF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FAF1.
VCP; NPLOC4; UFD1L; PLAA; CHM; G3BP1; SCHIP1; ITGB1BP1; IGF2; ANXA1; TK1; UROD; HSPA1A; SKIL; TNNT1; RCC1