faf1
Share
  • Official Full Name
  • Fas (TNFRSF6) associated factor 1
  • Background
  • FAF1 (Fas-associated protein factor 1) specifically interacts with the cytoplasmic domain of wild type, but not mutated Fas in both yeast and mammalian cells. When transiently expressed in T cells, FAF1 potentiates Fas-induced apoptosis. In contrast to TR
  • Synonyms
  • FAF1; Fas (TNFRSF6) associated factor 1; FAS-associated factor 1; CGI 03; hFAF1; HFAF1s; TNFRSF6 associated factor 1; UBX domain protein 3A; UBXD12; UBXN3A; TNFRSF6-associated factor 1; UBX domain-containing protein 12; UBX domain-containing protein 3A; C
Cat.#:FAF1-3647HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FAF1 Protein, GST-tagged
+Inquiry
Cat.#:FAF1-5435MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FAF1 Protein
+Inquiry
Cat.#:FAF1-2195RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FAF1 Protein
+Inquiry
Cat.#:FAF1-1541RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FAF1 Protein, His-tagged
+Inquiry
Cat.#:FAF1-12221ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish FAF1
+Inquiry
Cat.#:FAF1-6470HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FAF1 293 Cell Lysate
+Inquiry

Involved Pathway

FAF1 involved in several pathways and played different roles in them. We selected most pathways FAF1 participated on our site, such as FAS pathway and Stress induction of HSP regulation, RB in Cancer, TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FAF1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
FAS pathway and Stress induction of HSP regulation
DFFA; FAF1; LMNB2; DAXX
RB in Cancer
HLTF; PRMT2; RBP1; DCK; HMGB2; TOP2A; ANLN; RABIF; SMARCA2; FAF1
TNF-alpha/NF-kB Signaling Pathway
CAPN3; TXLNA; TNIP1; FAF1; RNF25; RNF216; LRPPRC; MARK2; CSNK2A1P; NKIRAS1

Protein Function

FAF1 has several biochemical functions, for example, NF-kappaB binding, heat shock protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FAF1 itself. We selected most functions FAF1 had, and list some proteins which have the same functions with FAF1. You can find most of the proteins on our site.
Function
Related Protein
Function NF-kappaB binding
Related Protein COMMD7; SNAI1A; RNF25; HDAC3; BRMS1; NFKBIA; COMMD6; DNAJA3; ANKRD42; AP1S2
Function heat shock protein binding
Related Protein DNAJA3; LMAN2; HSPA1B; BAK1; KCNJ11; GRXCR2; APAF1; GM5506; DNAJB6; DLST
Function protein binding
Related Protein SDPR; PPARGC1A; TRIM16; PTGES2; MED23; GSTP1; ACTR1B; CRADD; HAGH; IKZF1
Function protein domain specific binding
Related Protein AKAP1; DICER1; ODF1; KPNB1; RAPGEF3; IST1; PPARA; ARL1; VCP; STAMBP
Function protein kinase binding
Related Protein CALM3; JTB; MAVS; FAM83D; CCNK; USP37; DLG1; PARK2; SHC4; CD226
Function protein kinase regulator activity
Related Protein APC; KIDINS220B; ANKRD54; KIDINS220; FAF1; CDC37; CSNK2B; CDK5RAP1; RAC2
Function ubiquitin binding
Related Protein USP5; IDE; UBXN2B; NPLOC4; TNFAIP3; FAM125A; NEDD4; RBCK1; FAF2; CRY1
Function ubiquitin protein ligase binding
Related Protein RNF34; TSG101; MUL1; MAGEC2; FHIT; UBE2N; SPOP; GGN; SKI; UBE2L3

Interacting Protein

FAF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FAF1.
VCP; NPLOC4; UFD1L; PLAA; CHM; G3BP1; SCHIP1; ITGB1BP1; IGF2; ANXA1; TK1; UROD; HSPA1A; SKIL; TNNT1; RCC1