fastk
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  • Official Full Name
  • Fas-activated serine/threonine kinase
  • Background
  • The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.
  • Synonyms
  • FASTK; Fas-activated serine/threonine kinase; FAST; Fas activated serine threonine kinase; Fas activated serine threonine kinase isoform 1; Fas activated serine threonine kinase isoform 4; FAST kinase; FLJ13079
Cat.#:FASTK-3859HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FASTK Protein, GST-tagged
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Cat.#:FASTK-721HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FASTK Protein, His-tagged
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Cat.#:Fastk-722RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Fastk Protein, His-tagged
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Cat.#:FASTK-7653ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish FASTK
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Cat.#:FASTK-1402HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human FASTK (Active), GST-tagged
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Cat.#:FASTK-801HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human FASTK, GST-tagged
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Cat.#:FASTK-824HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Fas-activated Serine/Threonine Kinase, T7-tagged
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Cat.#:FASTK-6322HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FASTK 293 Cell Lysate
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Cat.#:FASTK-6323HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FASTK 293 Cell Lysate
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Protein Function

FASTK has several biochemical functions, for example, ATP binding, Fas-activated serine/threonine kinase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FASTK itself. We selected most functions FASTK had, and list some proteins which have the same functions with FASTK. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein KATNAL1; UCK1; CSNK1G2B; DYNC1LI1; DDX39A; PRKCE; EPHA10; STK24; KIF13B; LONP1
Function Fas-activated serine/threonine kinase activity
Related Protein FASTK
Function protein binding
Related Protein DCLRE1B; ZRANB1; TPPP; MST1R; POLG; MLST8; GPA33; PACSIN1; PIK3CG; ITK
Function protein serine/threonine kinase activity
Related Protein MAP4K1; CLK2; SNRKB; NEK8; BSK146; LATS1; RAF1; DCLK2; TESK1; PLK2B

Interacting Protein

FASTK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FASTK here. Most of them are supplied by our site. Hope this information will be useful for your research of FASTK.
WIPF1; TNKS2; HSP90AB1; CRK

FASTK Related Articles

Jourdain, AA; Koppen, M; et al. A Mitochondria-Specific Isoform of FASTK Is Present In Mitochondrial RNA Granules and Regulates Gene Expression and Function. CELL REPORTS 10:1110-1121(2015).
Zhi, F; Zhou, GX; et al. miR-106a-5p Inhibits the Proliferation and Migration of Astrocytoma Cells and Promotes Apoptosis by Targeting FASTK. PLOS ONE 8:-(2013).