Recombinant Human FASTK Protein, GST-tagged

• Cat.No.: FASTK-3859H
• Product Overview: Human FASTK full-length ORF ( NP_006703.1, 1 a.a. - 549 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 87.5 kDa
• AA Sequence: MRRPRGEPGPRAPRPTEGATCAGPG ESWSPSPNSMLRVLLSAQTSPARLS GLLLIPPVQPCCLGPSKWGDRPVGG GPSAGPVQGLQRLLEQAKSPGELLR WLGQNPSKVRAHHYSVALRRLGQLL GSRPRPPPVEQVTLQDLSQLIIRNC PSFDIHTIHVCLHLAVLLGFPSDGP LVCALEQERRLRLPPKPPPPLQPLL RGGQGLEAALSCPRFLRYPRQHLIS SLAEARPEELTPHVMVLLAQHLARH RLREPQLLEAIAHFLVVQETQLSSK VVQKLVLPFGRLNYLPLEQQFMPCL ERILAREAGVAPLATVNILMSLCQL RCLPFRALHFVFSPGFINYISGTPH ALIVRRYLSLLDTAVELELPGYRGP RLPRRQQVPIFPQPLITDRARCKYS HKDIVAEGLRQLLGEEKYRQDLTVP PGYCTDFLLCASSSGAVLPVRTQDP FLPYPPRSCPQGQAASSATTRDPAQ RVVLVLRERWHFCRDGRVLLGSRAL RERHLGLMGYQLLPLPFEELESQRG LPQLKSYLRQKLQALGLRWGPEGG
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FASTK Fas-activated serine/threonine kinase [ Homo sapiens ]
• Official Symbol: FASTK
• Synonyms: FASTK; Fas-activated serine/threonine kinase; fas-activated serine/threonine kinase; FAST; FAST kinase
• Gene ID: 10922
• mRNA Refseq: NM_006712
• Protein Refseq: NP_006703
• MIM: 606965
• UniProt ID: Q14296