Recombinant Human FASTK Protein, His-tagged
Cat.No. : | FASTK-01H |
Product Overview : | Recombinant human FASTK (200-535) protein with a N-terminal His-tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 38.2 kDa |
Protein length : | 200-535 |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade |
Concentration : | > 50 µg/mL as determined by microplate BCA method |
Storage Buffer : | 50mM Tris, 8M Urea, pH8.0 |
Gene Name : | FASTK Fas activated serine/threonine kinase [ Homo sapiens (human) ] |
Official Symbol : | FASTK |
Synonyms : | FASTK; Fas activated serine/threonine kinase; FAST; fas-activated serine/threonine kinase; FAST kinase |
Gene ID : | 10922 |
mRNA Refseq : | NM_001258461 |
Protein Refseq : | NP_001245390 |
MIM : | 606965 |
UniProt ID : | Q14296 |
Products Types
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionFASTK is a key protein regulating mitochondrial respiration, and knockdown of FASTK leads to mitochondrial respiratory dysfunction and apoptosis.
HBc proteins downregulate FASTK transcription and expression by repressing promoter activity.
FASTK interacts with the RNA-binding protein TIA1.
FASTK protein is localized to mitochondria.
FASTK functions in protein amino acid phosphorylation, apoptosis, signal transduction and extracellular signaling to guide apoptosis.
Customer Reviews (2)
Write a reviewProtein products are put into experiments with good effect and reliable experimental results.
The technical staff evaluated my experimental process and results and made many constructive comments.
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