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Recombinant Human FASTK Protein, His-tagged

Cat.No. : FASTK-01H
Product Overview : Recombinant human FASTK (200-535) protein with a N-terminal His-tag was expressed in E. coli.
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  • Gene Information
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Description : The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.
Source : E. coli
Species : Human
Tag : His
Molecular Mass : 38.2 kDa
Protein length : 200-535
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade
Concentration : > 50 µg/mL as determined by microplate BCA method
Storage Buffer : 50mM Tris, 8M Urea, pH8.0
Gene Name : FASTK Fas activated serine/threonine kinase [ Homo sapiens (human) ]
Official Symbol : FASTK
Synonyms : FASTK; Fas activated serine/threonine kinase; FAST; fas-activated serine/threonine kinase; FAST kinase
Gene ID : 10922
mRNA Refseq : NM_001258461
Protein Refseq : NP_001245390
MIM : 606965
UniProt ID : Q14296

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is FASTK involved in mitochondrial respiration? 11/10/2022

FASTK is a key protein regulating mitochondrial respiration, and knockdown of FASTK leads to mitochondrial respiratory dysfunction and apoptosis.

What is the relationship between HBc protein and FASTK protein? 08/13/2022

HBc proteins downregulate FASTK transcription and expression by repressing promoter activity.

How is FASTK related to the RNA-binding protein TIA1? 08/12/2022

FASTK interacts with the RNA-binding protein TIA1.

Where is the FASTK protein localized? 06/18/2021

FASTK protein is localized to mitochondria.

What is the biological function of FASTK? 03/13/2021

FASTK functions in protein amino acid phosphorylation, apoptosis, signal transduction and extracellular signaling to guide apoptosis.

Customer Reviews (2)

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Reviews
03/01/2021

    Protein products are put into experiments with good effect and reliable experimental results.

    12/04/2020

      The technical staff evaluated my experimental process and results and made many constructive comments.

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