FBP1 Protein, fructose-1,6-bisphosphatase 1

FBP1

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FBP1

Official Full Name fructose-1,6-bisphosphatase 1
Background Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.
Synonyms FBP1; fructose-1,6-bisphosphatase 1; FBP; 6-bisphosphatase 1; 6-bisphosphate 1-phosphohydrolase 1; D fructose 1 6 bisphosphate 1 phosphohydrolase 1; D-fructose-1; EC 3.1.3.11; F16P1_HUMAN; FBP 1; FBPase 1; Fructose 1 6 bisphosphatase 1; Fructose bisphosphatase 1; Fructose-1; Growth inhibiting protein 17; Liver fructose bisphosphatase; OTTHUMP00000021694; fructose-bisphosphatase 1; growth-inhibiting protein 17; D-fructose-1,6-bisphosphate 1-phosphohydrolase 1
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • SUMO
    • Myc
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Fbp1-1025M Recombinant Mouse Fbp1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human FBP1-1065H Recombinant Human FBP1 Mammalian Cell His
    Human FBP1-1207H Recombinant Human FBP1 Protein, His-SUMO/MYC-tagged E.coli His/SUMO/Myc
    Human FBP1-1815H Recombinant Human Fructose-1,6-bisphosphatase 1, His-tagged E.coli His
    Human FBP1-28810TH Recombinant Human FBP1, His-tagged E.coli His
    Human FBP1-3880H Recombinant Human FBP1 Protein, GST-tagged Wheat Germ GST
    Human FBP1-389H Recombinant Human FBP1 Protein, His-tagged E.coli His
    Human FBP1-6316HCL Recombinant Human FBP1 293 Cell Lysate HEK293 N/A
    Human FBP1-787H Recombinant Human FBP1 Protein, GST-tagged E.coli GST
    Human FBP1-788H Recombinant Human FBP1 Protein, His-tagged HEK293 His
    Mouse FBP1-5707M Recombinant Mouse FBP1 Protein Mammalian Cell His
    Rat FBP1-2283R Recombinant Rat FBP1 Protein Mammalian Cell His
    Rhesus Macaque FBP1-1651R Recombinant Rhesus monkey FBP1 Protein, His-tagged Mammalian Cell His
    Chicken FBP1-5329C Recombinant Chicken FBP1 Mammalian Cell His

    FBP1 involved in several pathways and played different roles in them. We selected most pathways FBP1 participated on our site, such as Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Fructose and mannose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with FBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycolysis / Gluconeogenesis HK1; FBP1A; ALDH3A2A; ALDOC; GPIB; PGK2; ALDH3A1; HK2; PFKL; TPI1B
    Pentose phosphate pathway GPI1; PGM2; ALDOC; FBP1; GPIB; PFKMB; DERA; TKT; PFKP; G6PD
    Fructose and mannose metabolism PFKFB4; PFKM; FUK; AKR1B10; GMDS; C12orf5; PFKP; DHRS13L1; GMPPAA; AKR1B8
    Metabolic pathways POLR3B; POLR3A; ATP6AP1B; MGAT3A; UGT2A2; BDH2; UGT2B7; PCK2; NMNAT3; CYP3A5
    Carbon metabolism PGK2; HAO1; CS; MCEE; PDHA1A; GPI1; ADH5; SDHDA; PCCB; PHGDH
    AMPK signaling pathway EEF2; RPS6KB1; CPT1C; EIF4EBP1; PIK3CB; STRADA; PPP2R2A; PFKFB3; STK11; PRKAG1
    Insulin signaling pathway PHKA1; PYGMA; SHC2; INS2; TSC2; PPP1CBL; SOCS1; PRKACA; PRKACB; SOCS1A
    Glucagon signaling pathway PDHB; PRKAG2; GYS2; CALM1; SMEK2; PPP3CC; GCG; PLCB1; PDE3B; PDHA1

    FBP1 has several biochemical functions, for example, AMP binding, fructose 1,6-bisphosphate 1-phosphatase activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBP1 itself. We selected most functions FBP1 had, and list some proteins which have the same functions with FBP1. You can find most of the proteins on our site.

    Function Related Protein
    AMP binding ACSS2; PRPS2; APRT; CYB5R3; ACSS1; PRKAG1; PRKAG2; PRPS1; FBP1; PYGL
    fructose 1,6-bisphosphate 1-phosphatase activity FBP1; FBP2; FBP1B; FBP1A
    identical protein binding HSPB8; TPCN1; NCAM1; FUS; PCM1; IMPA1; CLDNG; DVL1; TRA@; SH3GL3
    metal ion binding PLAGX; HDAC7A; ITGAL; CCDC76; ZNF562; ZNF680; ATP2B1; LHX2A; TRIM35-30; DZIP1L
    monosaccharide binding FBP1; RPIA; GPI1; Siglece; PGLS; GPR19; TALDO1; GPI; UPK1A
    protein binding ATP6AP2; RPS14; TMEM59; RBM26; C1D; C1QA; CKM; FAM192A; FCRL2; CRK

    FBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBP1.

    BIN1; FBP2; ACTN3; DYNC1I1; BUB1; TLR2

    Orino, K; Ishiji, T; et al. Characterization of bovine serum ferritin-binding proteins. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY 137:375-381(2004).
    Viudes, A; Perea, S; et al. Identification of continuous B-cell epitopes on the protein moiety of the 58-kilodalton cell wall mannoprotein of Candida albicans belonging to a family of immunodominant fungal antigens. INFECTION AND IMMUNITY 69:2909-2919(2001).

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