fbp1
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  • Official Full Name
  • fructose-1,6-bisphosphatase 1
  • Background
  • Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.
  • Synonyms
  • FBP1; fructose-1,6-bisphosphatase 1; FBP; 6-bisphosphatase 1; 6-bisphosphate 1-phosphohydrolase 1; D fructose 1 6 bisphosphate 1 phosphohydrolase 1; D-fructose-1; EC 3.1.3.11; F16P1_HUMAN; FBP 1; FBPase 1; Fructose 1 6 bisphosphatase 1; Fructose bisphosphatase 1; Fructose-1; Growth inhibiting protein 17; Liver fructose bisphosphatase; OTTHUMP00000021694; fructose-bisphosphatase 1; growth-inhibiting protein 17; D-fructose-1,6-bisphosphate 1-phosphohydrolase 1
Cat.#:FBP1-1207HTag:His-SUMO/MYC
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FBP1 Protein, His-SUMO/MYC-tagged
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Cat.#:FBP1-3880HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FBP1 Protein, GST-tagged
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Cat.#:FBP1-1065HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human FBP1
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Cat.#:FBP1-1815HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Fructose-1,6-bisphosphatase 1, His-tagged
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Cat.#:FBP1-28810THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FBP1, His-tagged
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Cat.#:FBP1-389HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human FBP1 Protein, His-tagged
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Cat.#:FBP1-787HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FBP1 Protein, GST-tagged
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Cat.#:FBP1-788HTag:His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human FBP1 Protein, His-tagged
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Cat.#:FBP1-5707MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FBP1 Protein
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Cat.#:FBP1-2283RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FBP1 Protein
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Cat.#:FBP1-1651RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FBP1 Protein, His-tagged
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Cat.#:FBP1-5329CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken FBP1
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Cat.#:FBP1-6316HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FBP1 293 Cell Lysate
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Involved Pathway

FBP1 involved in several pathways and played different roles in them. We selected most pathways FBP1 participated on our site, such as Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Fructose and mannose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with FBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Glycolysis / Gluconeogenesis
ALDH7A1; ALDH2.2; G6PC3; ALDOAB; GAPDHS; ALDOCB; TPI1; PCK2; PDHA1A; ENO3
Pentose phosphate pathway
PFKMB; TKTB; deoC; TKTL1; PRPS1B; H6PD; FBP1A; FBP2; FBP1; DERA
Fructose and mannose metabolism
ALDOB; HKDC1; ALDOCB; GMPPAA; TPI1; PFKP; PFKFB4L; AKR1B8; PFKMA; AKR1B1L
Metabolic pathways
ST20-MTHFS; PAICS; PDXK; GPI1; AMPD1; PNP; CBR2; RABGNT1; TKTL1; HSD3B1
Carbon metabolism
ENO3; RPIA; GPR19; GOT2; ackA; HK3; PRPS1B; OGDH; PGAM1; ECHS1
AMPK signaling pathway
PRKAB2; RAB2A; CAB39L; RAB14; EIF4EBP1; PPP2R2A; LIPE; IRS2; INS2; IRS1
Insulin signaling pathway
PHKG1; INSB; PPP1R3C; RPS6KB1B; SOCS1A; RHOQ; SOCS1; FBP1; CALM1; PTPN1
Glucagon signaling pathway
GCGR; ACACB; PLCB4; PHKA1; PKM2; PRMT1; PPARA; LDHAL6B; CALM1; SMEK2

Protein Function

FBP1 has several biochemical functions, for example, AMP binding, fructose 1,6-bisphosphate 1-phosphatase activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FBP1 itself. We selected most functions FBP1 had, and list some proteins which have the same functions with FBP1. You can find most of the proteins on our site.
Function
Related Protein
Function AMP binding
Related Protein PRKAG1; PRKAG2; PRPS1; PYGM; PRPS2; FBP1; ACSS2; CYB5R3; PYGL; APRT
Function fructose 1,6-bisphosphate 1-phosphatase activity
Related Protein FBP1B; FBP2; FBP1; FBP1A
Function identical protein binding
Related Protein SNRNP200; TPRG1L; NOD1; SMN1; KIRRELA; ZBTB16; PRPS2; C10orf88; SNX1; HCFC1
Function metal ion binding
Related Protein MEP1A.1; JAZF1; ZSCAN4D; ZFP746; METAP1; CA5; ZNF335; KSR1; ZNHIT2; CSH1
Function monosaccharide binding
Related Protein FBP1; GPI; RPIA; UPK1A; Siglece; GPR19; GPI1; TALDO1; PGLS
Function protein binding
Related Protein CCS; SMAGP; CBLB; JAM2; FNBP1; CDC27; IL28RA; KLHL35; GTF2B; NUP35

Interacting Protein

FBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of FBP1.
BIN1; FBP2; ACTN3; DYNC1I1; BUB1; TLR2

FBP1 Related Articles

Orino, K; Ishiji, T; et al. Characterization of bovine serum ferritin-binding proteins. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR & INTEGRATIVE PHYSIOLOGY 137:375-381(2004).
Viudes, A; Perea, S; et al. Identification of continuous B-cell epitopes on the protein moiety of the 58-kilodalton cell wall mannoprotein of Candida albicans belonging to a family of immunodominant fungal antigens. INFECTION AND IMMUNITY 69:2909-2919(2001).