Recombinant Full Length Human FBP1 Protein, C-Flag-tagged

• Cat.No.: FBP1-863HFL
• Product Overview: Recombinant Full Length Human FBP1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 36.7 kDa
• AA Sequence: MADQAPFDTDVNTLTRFVMEEGRKA RGTGELTQLLNSLCTAVKAISSAVR KAGIAHLYGIAGSTNVTGDQ VKKLDVLSNDLVMNMLKSSFATCVL VSEEDKHAIIVEPEKRGKYVVCFDP LDGSSNIDCLVSVGTIFGIY RKKSTDEPSEKDALQPGRNLVAAGY ALYGSATMLVLAMDCGVNCFMLDPA IGEFILVDKDVKIKKKGKIY SLNEGYARDFDPAVTEYIQRKKFPP DNSAPYGARYVGSMVADVHRTLVYG GIFLYPANKKSPNGKLRLLY
  ECNPMAYVMEKAGGMATTGKEAVLD VIPTDIHQRAPVILGSPDDVLEFLK VYEKHSAQTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Pentose phosphate pathway

Gene Information

• Gene Name: FBP1 fructose-bisphosphatase 1 [ Homo sapiens (human) ]
• Official Symbol: FBP1
• Synonyms: FBP
• Gene ID: 2203
• mRNA Refseq: NM_000507.4
• Protein Refseq: NP_000498.2
• MIM: 611570
• UniProt ID: P09467