fcgr3
Share
  • Official Full Name
  • FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
  • Background
  • CD16 is the low affinity IgG Fc receptor III (FcR III) and CD32 is FcR II. CD16/CD32 are expressed on B cells, monocytes/macrophages, NK cells, granulocytes, mast cells, and dendritic cells. The Fc receptors bind antibody-antigen immune complexes and mediate adaptive immune responses. It is useful for blocking non-specific binding of immunoglobulin to the Fc receptors.
  • Synonyms
  • FCGR3A; Fc fragment of IgG, low affinity IIIa, receptor (CD16a); Fc fragment of IgG, low affinity IIIa, receptor for (CD16) , FCG3, FCGR3; low affinity immunoglobulin gamma Fc region receptor III-A; CD16; CD16a; FcgammaRIIIA; CD16a antigen; fc-gamma RIII; Fc-gamma RIIIa; Fc-gamma RIII-alpha; igG Fc receptor III-2; Fc gamma receptor III-A; Fc-gamma receptor IIIb (CD16); neutrophil-specific antigen NA; Fc-gamma receptor III-2 (CD 16); immunoglobulin G Fc receptor III; Fc fragment of IgG, low affinity III, receptor for (CD16); FCG3; CD16A; FCGR3; IGFR3; FCR-10; FCRIII; FCGRIII; FCRIIIA;
Cat.#:FCGR3-1112MTag:His/AVI
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse FCGR3 Protein (Met1-Thr215), His-AVI-tagged, Biotinylated
+Inquiry
Cat.#:FCGR3-284CTag:His-Avi
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus FCGR3 Protein, His-Avi-tagged, Biotinylated
+Inquiry
Cat.#:Fcgr3-488MTag:His
Source (Host):NS0Species:Mouse
Product nameRecombinant Mouse Fc Receptor, LgG, Low Affinity III, His-tagged
+Inquiry
Cat.#:Fcgr3-4025MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Fcgr3, His tagged
+Inquiry
Cat.#:FCGR3-283CTag:His
Source (Host):HEK293Species:Cynomolgus
Product nameRecombinant Cynomolgus FCGR3 protein, His-tagged
+Inquiry
Cat.#:FCGR3-1677RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FCGR3 Protein, His-tagged
+Inquiry
Cat.#:FCGR3-4101CTag:His
Source (Host):HEK293Species:Rhesus Macaque
Product nameRecombinant Rhesus FCGR3 protein, His-tagged
+Inquiry
Cat.#:FCGR3-4103CTag:His/AVI
Source (Host):HEK293Species:Rhesus Macaque
Product nameRecombinant Rhesus FCGR3 protein, His/AVI-tagged
+Inquiry
Cat.#:FCGR3-2090MCLTag:
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse FCGR3 cell lysate
+Inquiry
Cat.#:FCGR3-1992CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus FCGR3 cell lysate
+Inquiry

Involved Pathway

FCGR3 involved in several pathways and played different roles in them. We selected most pathways FCGR3 participated on our site, such as Leishmaniasis, Natural killer cell mediated cytotoxicity, Osteoclast differentiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with FCGR3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Leishmaniasis
NCF4; NFKBIA; FOS; ITGB2L; HLA-DMA; IL12A; IL4; HLA-DQA2; TAB2; C3
Natural killer cell mediated cytotoxicity
IFNA14; MAPK3; RAC1; PTPN11; SHC4; MICB; PPP3CC; PIK3CA; HLA-C; TNFRSF10A
Osteoclast differentiation
PPP3CB; MAP3K14; PIK3R5; TGFBR2; SOCS3; LILRB3; FCGR4; MAPK3; FCGR2A; NFKB2
Phagosome
MBL2; HLA-G; THBS1; HLA-DOB; ITGB5; OLR1; TUBA8L2; TUBB; NOS1; HLA-DMB
Staphylococcus aureus infection
C3AR1; H2-AA; FCGR1; FPR1; C2; FCGR4; C1QC; ITGAL; HLA-DQA2; MASP1
Systemic lupus erythematosus
HIST1H4E; H2AFB3; HIST1H2AM; SNRPD3; FCGR3; H2AFX; FCGR1A; C1QC; HIST1H2AJ; HIST1H4D
Tuberculosis
HLA-DRB1; PLK3; ATP6V1H; IFNA4; KSR1; CALM2; PPP3CB; MYD88; RAB7; PPP3CC

FCGR3 Related Articles

Eckhardt, CL; Astermark, J; et al. The Fc gamma receptor IIa R131H polymorphism is associated with inhibitor development in severe hemophilia A. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 12:1294-1301(2014).
Bullich, G; Ballarin, J; et al. HLA-DQA1 and PLA2R1 Polymorphisms and Risk of Idiopathic Membranous Nephropathy. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 9:335-343(2014).