fgf17
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  • Official Full Name
  • fibroblast growth factor 17
  • Background
  • The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was shown to be prominently expressed in the cerebellum and cortex. The mouse homolog of this gene was localized to specific sites in the midline structures of the forebrain, the midbrain-hindbrain junction, developing skeleton and developing arteries, which suggests a role in central nervous system, bone and vascular development.This gene was referred to as FGF-13 in reference 2, however, its amino acid sequence and chromosomal localization are identical to FGF17.
  • Synonyms
  • FGF17; fibroblast growth factor 17; FGF 13; FGF13; FGF-17; OTTHUMP00000122553; OTTHUMP00000224730; FGF-13
Cat.#:FGF17-4106HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FGF17 Protein, GST-tagged
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Cat.#:FGF17-12866HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF17, GST-tagged
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Cat.#:FGF17-170HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Fibroblast Growth Factor 17
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Cat.#:FGF17-577HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human fibroblast growth factor 17, His-tagged
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Cat.#:FGF17-8552HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FGF17
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Cat.#:FGF17-5845MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FGF17 Protein
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Cat.#:Fgf17-8333MTag:
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Fgf17
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Cat.#:FGF17-2329RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat FGF17 Protein
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Cat.#:FGF17-1697RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FGF17 Protein, His-tagged
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Cat.#:FGF17-12818ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish FGF17
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Cat.#:FGF17-6245HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FGF17 293 Cell Lysate
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Involved Pathway

FGF17 involved in several pathways and played different roles in them. We selected most pathways FGF17 participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Rap signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with FGF17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
GADD45AB; RASGRP3; NFATC3; RASA2; MYCB; TRAF6; TGFBR1B; CACNB2; NR4A1; LAMTOR3
Ras signaling pathway
PRKACA; FGF14; BRAP; FGF7; PTPN11; PLA2G2A; STK4; RAC3; FGFR4; PLD2
Rap signaling pathway
CALM3; PRKD1; SIPA1L1; PRKCB; RAP1GAP; FGF3; KRIT1; MAPK11; Pdgfa&Pdgfb; FLT1
PIK-Akt signaling pathway
COL6A6; INS1; IKBKB; TSC2; HSP90B1; MAPK3; TNR; COL27A1; IL4; PCK1
Regulation of actin cytoskeleton
PTK2; DIAPH1; FGD3; VAV2; CDC42; FGF16; RRAS2; IQGAP2; PFN2; ACTN1
Pathways in cancer
HDAC1; GLI2; STAT1; TCEB2; FGF2; GNG13; TGFA; SUFU; CBLC; NFKBIA
Melanoma
NRAS; FGF14; FGF8; RB1; FGF1; FGF13; HGF; FGF17; RAF1; FGFR1

Protein Function

FGF17 has several biochemical functions, for example, growth factor activity, type 1 fibroblast growth factor receptor binding, type 2 fibroblast growth factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FGF17 itself. We selected most functions FGF17 had, and list some proteins which have the same functions with FGF17. You can find most of the proteins on our site.
Function
Related Protein
Function growth factor activity
Related Protein FGF11; BMP1; FGF8B; NRG4; BMP16; VEGFAA; VEGFAB; BMP15; FBRS; HGF
Function type 1 fibroblast growth factor receptor binding
Related Protein FGF17; NPTN; FGF8; FGF18
Function type 2 fibroblast growth factor receptor binding
Related Protein FGF8; FGF18; FGF10; FGF7; FGF17

FGF17 Related Articles

Campo, GM; Avenoso, A; et al. Beta-arrestin-2 negatively modulates inflammation response in mouse chondrocytes induced by 4-mer hyaluronan oligosaccharide. MOLECULAR AND CELLULAR BIOCHEMISTRY 399:201-208(2015).
Bob, F; Gluhovschi, G; et al. Immunohistochemical study of tubular epithelial cells and vascular endothelial cells in glomerulonephritis. RENAL FAILURE 36:1208-1214(2014).