fhl3
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  • Official Full Name
  • four and a half LIM domains 3
  • Background
  • The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • FHL3; four and a half LIM domains 3; four and a half LIM domains protein 3; SLIM2; FHL 3; Skeletal muscle LIM protein 2; FHL-3; SLIM-2; LIM-only protein FHL3; skeletal muscle LIM-protein 2
Cat.#:FHL3-4163HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human FHL3 Protein, GST-tagged
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Cat.#:FHL3-12890HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FHL3, GST-tagged
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Cat.#:FHL3-28894THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human FHL3, His-tagged
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Cat.#:FHL3-2914HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Four And A half LIM Domains 3, T7-tagged
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Cat.#:FHL3-328HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human four and a half LIM domains 3, His-tagged
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Cat.#:FHL3-5877MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse FHL3 Protein
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Cat.#:FHL3-1709RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey FHL3 Protein, His-tagged
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Cat.#:FHL3-6222HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human FHL3 293 Cell Lysate
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Protein Function

FHL3 has several biochemical functions, for example, actin binding, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FHL3 itself. We selected most functions FHL3 had, and list some proteins which have the same functions with FHL3. You can find most of the proteins on our site.
Function
Related Protein
Function actin binding
Related Protein GCSAM; MICAL2; CFL2; TNNI3; TNS1; SCIN; FSCN1; MYO9B; NEXN; SMTN
Function protein binding
Related Protein SEMG2; ASPSCR1; SALL4; CHEK1; TCEANC2; TMEM171; DNAJC19; RAD23A; FAM195A; ITGB1BP2
Function zinc ion binding
Related Protein RNF130; GATAD1; TRIM11; MLL1; JHDM1D; TRIM35-27; ZDHHC16A; TRIM35-35; ZNF75D; AGBL1

Interacting Protein

FHL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FHL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FHL3.
AIMP2; CNNM3; KLF3; WNK1; E2F8; MYBPHL

FHL3 Related Articles

Xia, WR; Fu, WL; et al. Angiogenin Promotes U87MG Cell Proliferation by Activating NF-kappa B Signaling Pathway and Downregulating Its Binding Partner FHL3. PLOS ONE 10:-(2015).
Molina-Navarro, MM; Trivino, JC; et al. Functional Networks of Nucleocytoplasmic Transport-Related Genes Differentiate Ischemic and Dilated Cardiomyopathies. A New Therapeutic Opportunity. PLOS ONE 9:-(2014).