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Official Full Name four and a half LIM domains 3
Background The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms FHL3; four and a half LIM domains 3; four and a half LIM domains protein 3; SLIM2; FHL 3; Skeletal muscle LIM protein 2; FHL-3; SLIM-2; LIM-only protein FHL3; skeletal muscle LIM-protein 2
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FHL3-12890H Recombinant Human FHL3, GST-tagged E.coli GST
    Human FHL3-28894TH Recombinant Human FHL3, His-tagged E.coli His
    Human FHL3-2914H Recombinant Human Four And A half LIM Domains 3, T7-tagged E.coli T7
    Human FHL3-328H Recombinant Human four and a half LIM domains 3, His-tagged E.coli His
    Human FHL3-4163H Recombinant Human FHL3 Protein, GST-tagged Wheat Germ GST
    Human FHL3-6222HCL Recombinant Human FHL3 293 Cell Lysate HEK293 N/A
    Mouse FHL3-5877M Recombinant Mouse FHL3 Protein Mammalian Cell His
    Rhesus Macaque FHL3-1709R Recombinant Rhesus monkey FHL3 Protein, His-tagged Mammalian Cell His

    FHL3 involved in several pathways and played different roles in them. We selected most pathways FHL3 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with FHL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    FHL3 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by FHL3 itself. We selected most functions FHL3 had, and list some proteins which have the same functions with FHL3. You can find most of the proteins on our site.

    Function Related Protein
    actin binding VMHC; SYN1; ARPC1A; INPPL1A; ADD1; ACE; MYH4; CORO7; DAAM1B; ENC1
    protein binding TULP1; TAF9B; FURIN; TMEM93; RNF43; TP63; RRAGD; NAA11; PLEKHG2; COL6A2
    zinc ion binding ADAM10; TRIM33; PDLIM3B; TADA2A; RNF220; TAF3; APOBEC3C; RNF215; ZMYM4; PRICKLE1A

    FHL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FHL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of FHL3.


    Xia, WR; Fu, WL; et al. Angiogenin Promotes U87MG Cell Proliferation by Activating NF-kappa B Signaling Pathway and Downregulating Its Binding Partner FHL3. PLOS ONE 10:-(2015).
    Molina-Navarro, MM; Trivino, JC; et al. Functional Networks of Nucleocytoplasmic Transport-Related Genes Differentiate Ischemic and Dilated Cardiomyopathies. A New Therapeutic Opportunity. PLOS ONE 9:-(2014).

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