GAB1

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GAB1

Official Full Name GAB1 GRB2-associated binding protein 1
Synonyms GAB1; GRB2-associated binding protein 1; GRB2-associated-binding protein 1; GRB2-associated binder 1; growth factor receptor bound protein 2-associated protein 1;
    • Species :
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GAB1-22H Recombinant Human GAB1 Protein, T7/His-tagged E. coli T7/His
    Human GAB1-1450H Recombinant Human GRB2-associated Binding Protein 1, His-tagged Sf9 Insect Cell His
    Human GAB1-1786H Recombinant Human GAB1 protein, His & T7-tagged E.coli His/T7
    Human GAB1-27493TH Recombinant Human GAB1, His-tagged His
    Human GAB1-4618H Recombinant Human GAB1 Protein, GST-tagged Wheat Germ GST
    Human GAB1-6075HCL Recombinant Human GAB1 293 Cell Lysate HEK293 N/A
    Human GAB1-6076HCL Recombinant Human GAB1 293 Cell Lysate HEK293 N/A
    Mouse Gab1-1787M Recombinant Mouse Gab1 protein, His & T7-tagged E.coli His/T7
    Rhesus Macaque GAB1-1785R Recombinant Rhesus monkey GAB1 Protein, His-tagged Mammalian Cell His
    Zebrafish GAB1-12537Z Recombinant Zebrafish GAB1 Mammalian Cell His

    GAB1 involved in several pathways and played different roles in them. We selected most pathways GAB1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with GAB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ErbB signaling pathway NRG2B; AKT2; AREGB; PIK3R3; MAP2K4B; AKT2L; TGFA; CAMK2D2; PRKCA; SRC
    Ras signaling pathway PRKACA; PLA2G6; MAPK1; FIGF; PLD2; RHOA; MAPK10; HGF; RASGRF2; Fasl
    Phospholipase D signaling pathway PLCG1; PLCB2; RRAS; GRB2; PIP5K1A; MAP2K2; PLD1; IL-8; GRM7; PIK3R3
    Neurotrophin signaling pathway TRAF6; NGFRAP1; SHC4; FOXO3; RAPGEF1; RHOA; PIK3R2; PSEN2; NRAS; MAPK12
    Bacterial invasion of epithelial cells CRK; SHC2; SEPT12; ACTG1; ILK; RHOA; CLTC; CBL; ARPC1B; CRKL
    Proteoglycans in cancer CBL; MAPK3; WNT9A; GPC1; WNT11; RRAS; TIMP3; MDM2; TGFB2; WNT10B
    Renal cell carcinoma PIK3CA; PIK3R2; ARNT; HRAS; EP300; PAK6; VEGFA; TGFB3; PIK3CB; ETS1

    GAB1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by GAB1 itself. We selected most functions GAB1 had, and list some proteins which have the same functions with GAB1. You can find most of the proteins on our site.

    Function Related Protein
    SH3/SH2 adaptor activity TOB1; EPS8; STAM; SLA2; GRB7; GRB2; ITSN2; SKAP1; IRS4; CRKL
    protein binding DDX42; HDAC1; VASP; RNF2; TNFAIP1; LRRC29; UBL4B; CDK8; FGD5; STAMBPL1
    signal transducer activity TMTOPS3B; GPR183A; MADD; PLCL2; OPN4A; TRIM54; TAS2R104; TAS2R137; EDNRBA; CNOT7

    GAB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GAB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of GAB1.

    PTPN11

    Pennacchietti, S; Cazzanti, M; et al. Microenvironment-Derived HGF Overcomes Genetically Determined Sensitivity to Anti-MET Drugs. CANCER RESEARCH 74:6598-6609(2014).
    Takeuchi, S; Wang, W; et al. Dual Inhibition of Met Kinase and Angiogenesis to Overcome HGF-Induced EGFR-TKI Resistance in EGFR Mutant Lung Cancer. AMERICAN JOURNAL OF PATHOLOGY 181:1034-1043(2012).

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