|Official Full Name||gap junction protein, alpha 4, 37kDa|
|Background||This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.|
|Synonyms||GJA4; gap junction protein, alpha 4, 37kDa; gap junction protein, alpha 4, 37kD (connexin 37) , gap junction protein, alpha 4, 37kDa (connexin 37); gap junction alpha-4 protein; connexin 37; CX37; Connexin-37; CXA4_HUMAN; Gap junction alpha 4 protein; gap junction protein, alpha 4 37kDa (connexin 37); gap junction protein, alpha 4, 37kD (connexin 37); OTTHUMP00000004181; OTTHUMP00000004182|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
GJA4 involved in several pathways and played different roles in them. We selected most pathways GJA4 participated on our site, such as Calcium Regulation in the Cardiac Cell, Gap junction assembly, Gap junction trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with GJA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Calcium Regulation in the Cardiac Cell||ADRB3; GJB5; CASQ1; GJA3; CASQ1B; CX55.5; RGS18; PKIG; KCNB1; RGS16|
|Gap junction assembly||GJB4; CX27.5; GJD3; GJB5; GJB7; CX30.3; GJB3; GJA8; GJB2; GJA4|
|Gap junction trafficking||GJB4; GJD3; DAB2; GJA5; MYO6; CX27.5; GJA4; GJC1; GJB5; MYO6A|
|Gap junction trafficking and regulation||GJB3; GJB2; GJA5; GJD3; GJA4; GJB4; GJA8; MYO6; GJB5; CX30.3|
|Membrane Trafficking||EXOC1; RAB10; TPD52; GJB5; STAM2; CPD; GJB2; PICALMA; GORASP1; TGOLN2|
|Ovarian Infertility Genes||SYNE2; MSH5; NR5A1; GJA4; INHA; ZP3; NRIP1; DAZL; DMC1; ZP2|
|Vesicle-mediated transport||HIP1R; SEC22C; FTH1A; RALAB; BLOC1S4; MYO6B; TRAPPC2L; TRAPPC9; STAB2; CX30.3|
GJA4 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GJA4 itself. We selected most functions GJA4 had, and list some proteins which have the same functions with GJA4. You can find most of the proteins on our site.
|protein binding||PINX1; RPP38; TPSAB1; TMEM66; DNAJC27; KRT25; CTCF; NID2; LCA5; CMTM5|
GJA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GJA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GJA4.
OPRM1; Oprd1; OPRK1