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Official Full Name gap junction protein, alpha 4, 37kDa
Background This gene encodes a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene have been associated with atherosclerosis and a higher risk of myocardial infarction.
Synonyms GJA4; gap junction protein, alpha 4, 37kDa; gap junction protein, alpha 4, 37kD (connexin 37) , gap junction protein, alpha 4, 37kDa (connexin 37); gap junction alpha-4 protein; connexin 37; CX37; Connexin-37; CXA4_HUMAN; Gap junction alpha 4 protein; gap junction protein, alpha 4 37kDa (connexin 37); gap junction protein, alpha 4, 37kD (connexin 37); OTTHUMP00000004181; OTTHUMP00000004182
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GJA4-26253TH Recombinant Human GJA4 Wheat Germ N/A
    Human GJA4-4922H Recombinant Human GJA4 Protein, GST-tagged Wheat Germ GST
    Human GJA4-5922HCL Recombinant Human GJA4 293 Cell Lysate HEK293 N/A
    Human GJA4-6996H Recombinant Human GJA4 protein, His-tagged E.coli His
    Mouse GJA4-6370M Recombinant Mouse GJA4 Protein Mammalian Cell His
    Mouse Gja4-6997M Recombinant Mouse Gja4 protein, His & GST-tagged E.coli His/GST
    Rat GJA4-2547R Recombinant Rat GJA4 Protein Mammalian Cell His
    Chicken GJA4-7107C Recombinant Chicken GJA4 Mammalian Cell His

    GJA4 involved in several pathways and played different roles in them. We selected most pathways GJA4 participated on our site, such as Calcium Regulation in the Cardiac Cell, Gap junction assembly, Gap junction trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with GJA4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Calcium Regulation in the Cardiac Cell ADRB3; GJB5; CASQ1; GJA3; CASQ1B; CX55.5; RGS18; PKIG; KCNB1; RGS16
    Gap junction assembly GJB4; CX27.5; GJD3; GJB5; GJB7; CX30.3; GJB3; GJA8; GJB2; GJA4
    Gap junction trafficking GJB4; GJD3; DAB2; GJA5; MYO6; CX27.5; GJA4; GJC1; GJB5; MYO6A
    Gap junction trafficking and regulation GJB3; GJB2; GJA5; GJD3; GJA4; GJB4; GJA8; MYO6; GJB5; CX30.3
    Membrane Trafficking EXOC1; RAB10; TPD52; GJB5; STAM2; CPD; GJB2; PICALMA; GORASP1; TGOLN2
    Ovarian Infertility Genes SYNE2; MSH5; NR5A1; GJA4; INHA; ZP3; NRIP1; DAZL; DMC1; ZP2
    Vesicle-mediated transport HIP1R; SEC22C; FTH1A; RALAB; BLOC1S4; MYO6B; TRAPPC2L; TRAPPC9; STAB2; CX30.3

    GJA4 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GJA4 itself. We selected most functions GJA4 had, and list some proteins which have the same functions with GJA4. You can find most of the proteins on our site.

    Function Related Protein
    protein binding PINX1; RPP38; TPSAB1; TMEM66; DNAJC27; KRT25; CTCF; NID2; LCA5; CMTM5

    GJA4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GJA4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GJA4.

    OPRM1; Oprd1; OPRK1

    Luana, NT; Sharma, N; et al. Characterization and cardiac differentiation of chicken spermatogonial stem cells. ANIMAL REPRODUCTION SCIENCE 151:244-255(2014).
    Berthoud, VM; Minogue, PJ; et al. Connexin50D47A Decreases Levels of Fiber Cell Connexins and Impairs Lens Fiber Cell Differentiation. INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE 54:7614-7622(2013).

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