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GJB3

  • Official Full Name

    gap junction protein, beta 3, 31kDa

  • Overview

    This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are;composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials;from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin;disorder. Alternative splicing results in multiple transcript variants encoding the same protein.
  • Synonyms

    GJB3; gap junction protein, beta 3, 31kDa; DFNA2, EKV, erythrokeratodermia variabilis , gap junction protein, beta 3, 31kD (connexin 31) , gap junction protein, beta 3, 31kDa (connexin 31); gap junction beta-3 protein; connexin 31; CX31; connexin-31; E;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bos taurus (Bovine)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GJB3-13278H Recombinant Human GJB3, His-tagged E.coli His C-term-170a.a.
Human GJB3-6998H Recombinant Human GJB3 protein, His-tagged E.coli His Cys211~Pro269 (Accession # O75712)
Human GJB3-5918HCL Recombinant Human GJB3 293 Cell Lysate HEK293 N/A
Human GJB3-5919HCL Recombinant Human GJB3 293 Cell Lysate HEK293 N/A
Human GJB3-1077H Recombinant Human GJB3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human GJB3-4930H Recombinant Human GJB3 Protein, GST-tagged Wheat Germ GST
Human GJB3-5295HF Recombinant Full Length Human GJB3 Protein, GST-tagged In Vitro Cell Free System GST 270 amino acids
Human GJB3-2610H Recombinant Human GJB3 Protein (Cys211-Pro269), N-GST tagged E.coli N-GST Cys211-Pro269
Mouse Gjb3-6999M Recombinant Mouse Gjb3 protein, His & GST-tagged E.coli His/GST Arg213~Ile270 (Accession # P28231)
Mouse Gjb3-3218M Recombinant Mouse Gjb3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat Gjb3-7000R Recombinant Rat Gjb3 protein, His & GST-tagged E.coli His/GST Val84~Val174
Rat GJB3-2553R Recombinant Rat GJB3 Protein Mammalian Cell His
Rat GJB3-2209R-B Recombinant Rat GJB3 Protein Pre-coupled Magnetic Beads HEK293
Rat GJB3-2209R Recombinant Rat GJB3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Bos taurus (Bovine) RFL7401BF Recombinant Full Length Bovine Gap Junction Beta-3 Protein(Gjb3) Protein, His-Tagged E.coli expression system His Full Length (1-270)
Homo sapiens (Human) RFL4086HF Recombinant Full Length Human Gap Junction Beta-3 Protein(Gjb3) Protein, His-Tagged E.coli expression system His Full Length (1-270)
Mus musculus (Mouse) RFL17570MF Recombinant Full Length Mouse Gap Junction Beta-3 Protein(Gjb3) Protein, His-Tagged E.coli expression system His Full Length (1-270)
Rattus norvegicus (Rat) RFL4261RF Recombinant Full Length Rat Gap Junction Beta-3 Protein(Gjb3) Protein, His-Tagged E.coli expression system His Full Length (1-270)
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GJB3 involved in several pathways and played different roles in them. We selected most pathways GJB3 participated on our site, such as Calcium Regulation in the Cardiac Cell, Gap junction assembly, Gap junction trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with GJB3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium Regulation in the Cardiac CellKCNB1;CX55.5;PKIB;YWHAQ;RGS5B;CHRM1;ANXA6;GJA5;CX30.3
Gap junction assemblyGJA4;GJA5;GJB7;GJB4;GJB2;GJB3;CX27.5;CX30.3;GJD3
Gap junction traffickingGJA8;GJC1;GJB2;MYO6A;MYO6;GJB4;CX27.5;GJB5;DAB2
Gap junction trafficking and regulationGJB5;DAB2;GJB4;MYO6;GJA5;MYO6B;GJD3;GJB7;CX30.3
Membrane TraffickingTRAPPC6BL;AP3S1;TPD52L1;CNIH;CLVS1;TRAPPC1;CX30.3;SNAPIN;STXBP3
Vesicle-mediated transportRALAA;AP4B1;YIPF6;PICALM;TRAPPC6A;CNO;AMBP;NECAP1;SNAPIN

GJB3 has several biochemical functions, for example, gap junction channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GJB3 itself. We selected most functions GJB3 had, and list some proteins which have the same functions with GJB3. You can find most of the proteins on our site.

Function Related Protein
gap junction channel activityGJC2;CX23;GJB2;GJA8;GJA10;PANX2;GJA1;GJD3;CX52.6

GJB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GJB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GJB3.

ELAVL1

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