gjb3
Share
  • Official Full Name
  • gap junction protein, beta 3, 31kDa
  • Background
  • This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are;composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials;from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin;disorder. Alternative splicing results in multiple transcript variants encoding the same protein.
  • Synonyms
  • GJB3; gap junction protein, beta 3, 31kDa; DFNA2, EKV, erythrokeratodermia variabilis , gap junction protein, beta 3, 31kD (connexin 31) , gap junction protein, beta 3, 31kDa (connexin 31); gap junction beta-3 protein; connexin 31; CX31; connexin-31; E
Cat.#:GJB3-4930HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GJB3 Protein, GST-tagged
+Inquiry
Cat.#:GJB3-13278HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GJB3, His-tagged
+Inquiry
Cat.#:GJB3-6998HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GJB3 protein, His-tagged
+Inquiry
Cat.#:Gjb3-6999MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Gjb3 protein, His & GST-tagged
+Inquiry
Cat.#:GJB3-2553RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GJB3 Protein
+Inquiry
Cat.#:Gjb3-7000RTag:His/GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Gjb3 protein, His & GST-tagged
+Inquiry
Cat.#:GJB3-5918HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GJB3 293 Cell Lysate
+Inquiry
Cat.#:GJB3-5919HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GJB3 293 Cell Lysate
+Inquiry

Involved Pathway

GJB3 involved in several pathways and played different roles in them. We selected most pathways GJB3 participated on our site, such as Calcium Regulation in the Cardiac Cell, Gap junction assembly, Gap junction trafficking, which may be useful for your reference. Also, other proteins which involved in the same pathway with GJB3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Calcium Regulation in the Cardiac Cell
CX30.3; PKIG; RGS18; CHRM1; CHRM2; ADRA1B; RGS6; KCNB1; ADRB1; CASQ2
Gap junction assembly
GJB5; GJB4; GJB2; GJA8; GJA4; CX27.5; CX30.3; GJC1; GJB7; GJB3
Gap junction trafficking
GJA5; GJA8; GJB3; MYO6A; GJB5; GJA4; GJD3; GJB7; GJB2; MYO6
Gap junction trafficking and regulation
GJD3; DAB2; GJA8; GJB3; CX27.5; GJB7; MYO6A; GJB5; GJB4; CX30.3
Membrane Trafficking
CNIH2; TRAPPC6B; TRAPPC6BL; GORASP1; TRAPPC6A; PREB; SNX9A; SEC22A; GAK; ARCN1A
Vesicle-mediated transport
NECAP1; SCFD1; RALAB; TRAPPC3; PPP6C; BLOC1S6; CTAGE5; TRAPPC2; GJB4; CLVS2

Protein Function

GJB3 has several biochemical functions, for example, gap junction channel activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GJB3 itself. We selected most functions GJB3 had, and list some proteins which have the same functions with GJB3. You can find most of the proteins on our site.
Function
Related Protein
Function gap junction channel activity
Related Protein GJA10; GJA8; GJD3; GJA1; GJB3; CX23; GJC2; CX43; CX30.3; CX52.6

Interacting Protein

GJB3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GJB3 here. Most of them are supplied by our site. Hope this information will be useful for your research of GJB3.
ELAVL1