Recombinant Human GJB3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: GJB3-1077H
• Product Overview: GJB3 MS Standard C13 and N15-labeled recombinant protein (NP_001005752) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein.
• Molecular Mass: 30.8 kDa
• AA Sequence: MDWKTLQALLSGVNKYSTAFGRIWLSVVFVFRVLVYVVAAERVWGDEQKDFDCNTKQPGCTNVCYDNYFPISNIRLWALQLIFVTCPSLLVILHVAYREERERRHRQKHGDQCAKLYDNAGKKHGGLWWTYLFSLIFKLIIEFLFLYLLHTLWHGFNMPRLVQCANVAPCPNIVDCYIARPTEKKIFTYFMVGASAVCIVLTICELCYLICHRVLRGLHKDKPRGGCSPSSSASRASTCRCHHKLVEAGEVDPDPGNNKLQASAPNLTPITRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: GJB3 gap junction protein beta 3 [ Homo sapiens (human) ]
• Official Symbol: GJB3
• Synonyms: GJB3; gap junction protein, beta 3, 31kDa; DFNA2, EKV, erythrokeratodermia variabilis, gap junction protein, beta 3, 31kD (connexin 31), gap junction protein, beta 3, 31kDa (connexin 31); gap junction beta-3 protein; connexin 31; CX31; connexin-31; EKV; DFNA2; DFNA2B; FLJ22486; MGC102938
• Gene ID: 2707
• mRNA Refseq: NM_001005752
• Protein Refseq: NP_001005752
• MIM: 603324
• UniProt ID: O75712