Expand| Cat.No. : | GJB3-6998H |
| Product Overview : | Recombinant Human GJB3 aa. (Cys211~Pro269 (Accession # O75712)) fused with N-terminal His tag was produced in E. coli cells. |
| Description : | This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His |
| Form : | Freeze-dried powder |
| Molecular Mass : | 7 kDa as determined by SDS-PAGE reducing conditions. |
| Protein length : | Cys211~Pro269 (Accession # O75712) |
| Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
| Purity : | >95% |
| Characteristic : | The isoelectric point is 8.9. |
| Applications : | SDS-PAGE; WB; ELISA; IP |
| Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
| Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
| Storage buffer : | Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4. |
| Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
| Gene Name : | GJB3 gap junction protein beta 3 [ Homo sapiens (human) ] |
| Official Symbol : | GJB3 |
| Synonyms : | GJB3; gap junction protein beta 3; EKV; CX31; DFNA2; EKVP1; DFNA2B; gap junction beta-3 protein; connexin 31; gap junction protein, beta 3, 31kDa |
| Gene ID : | 2707 |
| mRNA Refseq : | NM_001005752.1 |
| Protein Refseq : | NP_001005752.1 |
| UniProt ID : | O75712 |
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