Recombinant Human GJB3 protein, His-tagged

• Cat.No.: GJB3-6998H
• Product Overview: Recombinant Human GJB3 aa. (Cys211~Pro269 (Accession # O75712)) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Cys211~Pro269
• Description: This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein.
• Form: Freeze-dried powder
• Molecular Mass: 7 kDa as determined by SDS-PAGE reducing conditions.
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 8.9.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: GJB3 gap junction protein beta 3 [ Homo sapiens (human) ]
• Official Symbol: GJB3
• Synonyms: GJB3; gap junction protein beta 3; EKV; CX31; DFNA2; EKVP1; DFNA2B; gap junction beta-3 protein; connexin 31; gap junction protein, beta 3, 31kDa
• Gene ID: 2707
• mRNA Refseq: NM_001005752.1
• Protein Refseq: NP_001005752.1
• UniProt ID: O75712