"GJB3" Related Products


Recombinant Human GJB3 protein, His-tagged

Cat.No. : GJB3-6998H
Product Overview : Recombinant Human GJB3 aa. (Cys211~Pro269 (Accession # O75712)) fused with N-terminal His tag was produced in E. coli cells.
Description : This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene can cause non-syndromic deafness or erythrokeratodermia variabilis, a skin disorder. Alternative splicing results in multiple transcript variants encoding the same protein.
Source : E. coli
Species : Human
Tag : His
Form : Freeze-dried powder
Molecular Mass : 7 kDa as determined by SDS-PAGE reducing conditions.
Protein length : Cys211~Pro269 (Accession # O75712)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 8.9.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as liquid form in Phosphate buffered saline(PBS), pH 7.4.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name : GJB3 gap junction protein beta 3 [ Homo sapiens (human) ]
Official Symbol : GJB3
Synonyms : GJB3; gap junction protein beta 3; EKV; CX31; DFNA2; EKVP1; DFNA2B; gap junction beta-3 protein; connexin 31; gap junction protein, beta 3, 31kDa
Gene ID : 2707
mRNA Refseq : NM_001005752.1
Protein Refseq : NP_001005752.1
UniProt ID : O75712

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