gpr55
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  • Official Full Name
  • G protein-coupled receptor 55
  • Background
  • Members of the G protein-coupled receptor (GPR) family, such as GPR55, play important roles in signal transduction from;the external environment to the inside of the cell (Sawzdargo et al., 1999 (PubMed 9931487)).
  • Synonyms
  • GPR55; G protein-coupled receptor 55; G-protein coupled receptor 55; G protein coupled receptor 55; GPCR GPR55; GPR 55; Probable G protein coupled receptor 55
Cat.#:GPR55-5252HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GPR55 Protein
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Cat.#:GPR55-5783HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human GPR55 293 Cell Lysate
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Cat.#:Kit-1320Tag:
Source (Host):Species:
Product nameGPR55 CHO-K1 β-Arrestin GPCR Assay Kit
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Cat.#:Kit-0906Tag:
Source (Host):Species:
Product nameTR-FRET PPAR delta Coactivator Assay Kit, rabbit
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Cat.#:CSC-RG0196Tag:
Source (Host):Species:Human
Product nameHuman GPR55-FLAG Stable Cell Line-HEK293T
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Cat.#:CSC-RG0426Tag:
Source (Host):Species:Human
Product nameHuman GPR55-FLAG Stable Cell Line-HEK293T
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Involved Pathway

GPR55 involved in several pathways and played different roles in them. We selected most pathways GPR55 participated on our site, such as Class A/1 (Rhodopsin-like receptors), G alpha (i) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with GPR55 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Class A/1 (Rhodopsin-like receptors)
ACKR4; S1PR3; S1PR1; SSTR1; TAC2; LPAR2A; SSTR3; CCR3; OPN4.1; OPN4B
G alpha (i) signalling events
FPR-RS4; ANXA1B; CASR; OXGR1A.1; SSTR1; PYYA; CCL19A.2; RGS20; OPN1MW; RLN3
GPCR downstream signaling
GNA13B; OPN1LW1; KALRNB; TRIO; OXGR1A.3; ADCYAP1R1; RGS14; NMB; PTGDR2; RHOL
GPCR ligand binding
LTB4R; APLN; FPR-RS4; EDN3; ADM2A; RLN3A; OXGR1A.1; GPR68; CRHR2; FZD10
GPCRs, Other
EMR2; GPR88; GPR132; VMN1R46; VMN1R54; RRH; CELSR3; OR10A5; CELSR2; VMN1R41
Signal Transduction
ARHGAP26; RGS1; RTN4A; BCO2; NMT1A; RHOV; RPE65B; CIT; LINGO1; ADM2A
Signaling by GPCR
CRHB; RGS11; OBSCN; ARHGEF16; PYYA; TRH; NET1; OXER1; OPN4B; PTH

Protein Function

GPR55 has several biochemical functions, for example, G-protein coupled receptor activity, cannabinoid receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GPR55 itself. We selected most functions GPR55 had, and list some proteins which have the same functions with GPR55. You can find most of the proteins on our site.
Function
Related Protein
Function G-protein coupled receptor activity
Related Protein EMR2; CCR12A; TAAR13C; OLFR149; V2RH7; CXCR3.2; HTR1AB; LPAR3; OR115-6; VMN1R54
Function cannabinoid receptor activity
Related Protein CNR2; GPR55; CNR1

GPR55 Related Articles

Chiurchiu, V; Lanuti, M; et al. The differential characterization of GPR55 receptor in human peripheral blood reveals a distinctive expression in monocytes and NK cells and a proinflammatory role in these innate cells. INTERNATIONAL IMMUNOLOGY 27:153-160(2015).
Jenkin, KA; McAinch, AJ; et al. Elevated cannabinoid receptor 1 and G protein-coupled receptor 55 expression in proximal tubule cells and whole kidney exposed to diabetic conditions. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY 42:256-262(2015).