GRIK4 Protein, glutamate receptor, ionotropic, kainate 4

GRIK4

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GRIK4

Official Full Name glutamate receptor, ionotropic, kainate 4
Background This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members.
Synonyms GRIK4; glutamate receptor, ionotropic, kainate 4; GRIK; glutamate receptor, ionotropic kainate 4; GluK4; KA1; glutamate receptor KA1; glutamate receptor KA-1; excitatory amino acid receptor 1; EAA1
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GRIK4-29879TH Recombinant Human GRIK4 Wheat Germ N/A
    Human GRIK4-5340H Recombinant Human GRIK4 Protein, GST-tagged Wheat Germ GST
    Mouse GRIK4-7267M Recombinant Mouse GRIK4 Protein Mammalian Cell His
    Rat GRIK4-2698R Recombinant Rat GRIK4 Protein Mammalian Cell His

    GRIK4 involved in several pathways and played different roles in them. We selected most pathways GRIK4 participated on our site, such as Neuroactive ligand-receptor interaction, Glutamatergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with GRIK4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Neuroactive ligand-receptor interaction TACR3; GABRA3; SSTR1; TACR3A; GABRQ; PRLHR; TACR3L; HTR5A; NMUR2; GRM8B
    Glutamatergic synapse GRM6; PRKCA; SHANK1; GRM3; PLCB3; DLGAP1; GNB2; GRM4; GNGT1; GRIN3B

    GRIK4 has several biochemical functions, for example, extracellular-glutamate-gated ion channel activity, kainate selective glutamate receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GRIK4 itself. We selected most functions GRIK4 had, and list some proteins which have the same functions with GRIK4. You can find most of the proteins on our site.

    Function Related Protein
    extracellular-glutamate-gated ion channel activity GRIN2B; GRIK4; GRIA1B; GRIA1; GRIK2; GRIN3B; GRIN1A; GRID2; GRIA3A; GRIA4B
    kainate selective glutamate receptor activity GRIK3; GRIK5; GRIK2; GRIK4; GRIK1

    GRIK4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GRIK4 here. Most of them are supplied by our site. Hope this information will be useful for your research of GRIK4.

    Trippe, J; Steinke, K; et al. Autoantibodies to Glutamate Receptor Antigens in Multiple Sclerosis and Rasmussen's Encephalitis. NEUROIMMUNOMODULATION 21:189-194(2014).
    Balasuriya, D; Goetze, TA; et al. alpha-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid (AMPA) and N-Methyl-D-aspartate (NMDA) Receptors Adopt Different Subunit Arrangements. JOURNAL OF BIOLOGICAL CHEMISTRY 288:-(2013).

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