gss
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  • Official Full Name
  • glutathione synthetase
  • Background
  • Glutathione (GSH), a ubiquitous low molecular mass thiol, is important for a variety of biological functions including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. GSH synthetase acts a
  • Synonyms
  • GSS; glutathione synthetase; GSH-S; GSH synthetase; glutathione synthase; GSHS; MGC14098
Cat.#:GSS-4406HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human GSS Protein, GST-tagged
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Cat.#:GSS-26092THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GSS, His-tagged
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Cat.#:GSS-807HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GSS Protein, His-tagged
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Cat.#:GSS-7323MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse GSS Protein
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Cat.#:Gss-8212MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Gss protein, His-tagged
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Cat.#:GSS-2731RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat GSS Protein
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Cat.#:Gss-8213RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Gss protein, His-tagged
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Cat.#:GSS-570CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus GSS Protein, His-tagged
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Cat.#:GSS-1610ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish GSS
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Cat.#:GSS-2870HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human GSS, His-tagged
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Cat.#:GSS-5720HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human GSS 293 Cell Lysate
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Involved Pathway

GSS involved in several pathways and played different roles in them. We selected most pathways GSS participated on our site, such as Cysteine and methionine metabolism, Glutathione metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with GSS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cysteine and methionine metabolism
MAT2AL; MAT2AB; TAT; LDHB; AMD1; DNMT3AB; MPST; GOT2B; GCLC; GSS
Glutathione metabolism
GSTK1; GGCT; GSTM7; MGST2; GSTAL; LAP3; GSTA; GSTT2; GSTP2; GSTM
Metabolic pathways
POLR3H; MTAP; MT-ATP6; B3GNTL2; ACAT2; SYNJ1; RPN1; ACER1; PANK4; GNSB

Protein Function

GSS has several biochemical functions, for example, ATP binding, glutathione binding, glutathione synthase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by GSS itself. We selected most functions GSS had, and list some proteins which have the same functions with GSS. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein FARS2; TEP1; PI4KB; STK30; Abcb1b; PAK6; ERBB2; ATP1A3; UBE2QL1; GATC
Function glutathione binding
Related Protein PTGES; GSTM2; LANCL1; GSTM7; MGST1; GPX1; GSTM4; GSS; LTC4S; GSTM3
Function glutathione synthase activity
Related Protein GSS
Function glycine binding
Related Protein GRIN3B; SIX2A; SRR; GLRA4B; GLRA4A; GSS; ALAS2; GLRA2; GRIN1; GLDC
Function magnesium ion binding
Related Protein SRPK1; TESC; IDH3G; ALPP; ATP8A1; NUDT3; PKM; CIB2; FARS2; RPS6KAL
Function protein binding
Related Protein LLGL2; WRN; PAX6; APBB1; PARL; CDC37L1; HDAC2; RIPPLY1; KLF12; APOB
Function protein homodimerization activity
Related Protein ENPP1; RELA; TAP1; CORO1A; CHKA; TPD52L2; CEACAM5; PVRL1; Defa-rs7; MAP3K11

Interacting Protein

GSS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GSS here. Most of them are supplied by our site. Hope this information will be useful for your research of GSS.
TERF1; GAPDH; IRF3

GSS Related Articles

Fujita, K; Shimomura, M; et al. Serum Fucosylated Haptoglobin as a Novel Prognostic Biomarker Predicting High-Gleason Prostate Cancer. PROSTATE 74:1052-1058(2014).
Jones, M; Odunsi, S; et al. Gerstmann-Straussler-Scheinker disease Novel PRNP mutation and VGKC-complex antibodies. NEUROLOGY 82:2107-2111(2014).