Recombinant Human GSS Protein, GST-tagged

• Cat.No.: GSS-4406H
• Product Overview: Human GSS full-length ORF ( AAH07927, 1 a.a. - 474 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 77.77 kDa
• AA Sequence: MATNWGSLLQDKQQLEELARQAVDR ALAEGVLLRTSQEPTSSEVVSYAPF TLFPSLVPSALLEQAYAVQMDFNLL VDAVSQNAAFLEQTLSSTIKQDDFT ARLFDIHKQVLKEGIAQTVFLGLNR SDYMFQRSADGSPALKQIEINTISA SFGGLASRTPAVHRHVLSVLSKTKE AGKILSNNPSKGLALGIAKAWELYG SPNALVLLIAQEKERNIFDQRAIEN ELLARNIHVIRRTFEDISEKGSLDQ DRRLFVDGQEIAVVYFRDGYMPRQY SLQNWEARLLLERSHAAKCPDIATQ LAGTKKVQQELSRPGMLEMLLPGQP EAVARLRATFAGLYSLDVGEEGDQA IAEALAAPSRFVLKPQREGGGNNLY GEEMVQALKQLKDSEERASYILMEK IEPEPFENCLLRPGSPARVVQCISE LGIFGVYVRQEKTLVMNKHVGHLLR TKAIEHADGGVAAGVAVLDNPYPV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: GSS glutathione synthetase [ Homo sapiens ]
• Official Symbol: GSS
• Synonyms: GSS; glutathione synthetase; GSH-S; GSH synthetase; glutathione synthase; GSHS; MGC14098
• Gene ID: 2937
• mRNA Refseq: NM_000178
• Protein Refseq: NP_000169
• MIM: 601002
• UniProt ID: P48637