Recombinant Human GSS Protein, His-tagged

• Cat.No.: GSS-807H
• Product Overview: Recombinant Human GSS(Ala2-Val474) fused with His tag at C-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 2-474 a.a.
• Description: Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
• Form: 20mM Tris-HCl, 200mM NaCl, pH 7.5. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 53.5 kDa
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: GSS glutathione synthetase [ Homo sapiens ]
• Official Symbol: GSS
• Synonyms: GSS; glutathione synthetase; GSH-S; GSH synthetase; glutathione synthase; GSHS; MGC14098
• Gene ID: 2937
• mRNA Refseq: NM_000178
• Protein Refseq: NP_000169
• MIM: 601002
• UniProt ID: P48637