Human GSS Knockdown Cell Lysate

• Cat.No.: GSS-190HKCL
• Product Overview: WB-validated GSS Knockdown HeLa Cell Lysate

Specification

• Species: Human
• Source: HeLa
• Tag: Non
• Description: Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
• Form: Cell-Tissue Lysis buffer
• Molecular Mass: 52 kDa
• Notes: Instruction of use: This knockdown cell lysate should be paired with wild-type HeLa cell lysate for use. For Western blotting, we recommend running wild-type and knockdown lysates on the same gel, and loading each well with equal volume and equal amount of total proteins.
• Storage: Store at -20 centigrade for two years.
• Concentration: Lot-specific
• Shipping: Blue Ice
• Components: 1 vial of 100 μg WT HeLa cell lysate 1 vial of 100 μg GSS KD HeLa cell lysate
• Protein Families: Druggable Genome
• Protein Pathways: Glutathione metabolism, Metabolic pathways
• Lysate QC: RT-qPCR; Western Blotting (WB)

Gene Information

• Gene Name: GSS glutathione synthetase [ Homo sapiens (human) ]
• Official Symbol: GSS
• Synonyms: GSS; glutathione synthetase; GSH-S; GSH synthetase; glutathione synthase; GSHS; MGC14098
• Gene ID: 2937
• mRNA Refseq: NM_000178
• Protein Refseq: NP_000169
• MIM: 601002
• UniProt ID: P48637