|Official Full Name||H2A histone family, member B2|
|Background||Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. This gene is part of a region that is repeated three times on chromosome X, once in intron 22 of the F8 gene and twice closer to the Xq telomere. This record represents the middle copy. [provided by RefSeq, Jul 2008]|
|Synonyms||H2AFB2; H2A histone family, member B2; H2A.Bbd; histone H2A-Bbd type 2/3; H2A Barr body deficient; H2A Barr body-deficient;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
H2AFB2 involved in several pathways and played different roles in them. We selected most pathways H2AFB2 participated on our site, such as Alcoholism, Systemic lupus erythematosus, which may be useful for your reference. Also, other proteins which involved in the same pathway with H2AFB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Alcoholism||ADORA2B; SHC4; HIST1H2BG; GRIN3A; HDAC3; DRD1A; HIST1H2AE; GM14476; HIST1H2BL; DDC|
|Systemic lupus erythematosus||HIST1H2BD; GM14483; C7; FCGR4; HIST1H2AC; HIST1H2AP; CD40; H2AFY2; SNRPD3; HIST1H2AF|
H2AFB2 has several biochemical functions, for example, DNA binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by H2AFB2 itself. We selected most functions H2AFB2 had, and list some proteins which have the same functions with H2AFB2. You can find most of the proteins on our site.
|DNA binding||PHC2; ZNF823; ZKSCAN17; HOXA5; IFIH1; ZBTB8A; ZNF143B; MYCB; DBX1B; MTF2|
|protein heterodimerization activity||HIST1H2AG; PIK3R2; BDKRB2; RELA; TAF13; HIST1H4C; SOX5; RALGAPA1; H2-Q10; FLOT2|
H2AFB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with H2AFB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of H2AFB2.