hat1
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  • Official Full Name
  • histone acetyltransferase 1
  • Background
  • The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene.
  • Synonyms
  • HAT1; histone acetyltransferase 1; histone acetyltransferase type B catalytic subunit; KAT1; HAT 1; HAT1_HUMAN; Histidine aminotransferase 1; OTTHUMP00000163124
Cat.#:HAT1-4586HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HAT1 Protein, GST-tagged
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Cat.#:HAT1-569HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Histone Acetyltransferase 1, His-tagged
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Cat.#:Hat1-2007MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Hat1 protein, His & T7-tagged
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Cat.#:HAT1-7488MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse HAT1 Protein
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Cat.#:HAT1-2793RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat HAT1 Protein
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Cat.#:HAT1-5781CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken HAT1
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Cat.#:HAT1-1294ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish HAT1
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Cat.#:HAT1-5631HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human HAT1 293 Cell Lysate
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Involved Pathway

HAT1 involved in several pathways and played different roles in them. We selected most pathways HAT1 participated on our site, such as Alcoholism, which may be useful for your reference. Also, other proteins which involved in the same pathway with HAT1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Alcoholism
HIST1H3I; GRB2; H2AFB2; HDAC11; GNG5; GNAI1; HIST1H3C; HDAC7A; DRD1; HAT1

Protein Function

HAT1 has several biochemical functions, for example, H4 histone acetyltransferase activity, histone acetyltransferase activity, histone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HAT1 itself. We selected most functions HAT1 had, and list some proteins which have the same functions with HAT1. You can find most of the proteins on our site.
Function
Related Protein
Function H4 histone acetyltransferase activity
Related Protein NAA60; BRCA2; ELP3; NAA50; HAT1; NAT15
Function histone acetyltransferase activity
Related Protein CREBBP; KAT2A; KAT7A; MED24; vnc; HAT1; EP300; TAF1L; METTL8; KAT5
Function histone binding
Related Protein H2AFX; HAT1; HIST1H3I; HIST1H3C; NAP1L2; NPM2; HIST1H4B; HIST1H4J; DEK; PRMT7
Function protein binding
Related Protein TNS4; ETV7; VASP; FCGR2A; BCL2L10; SRF; SNX18; ZNF238; THEMIS; SLC8A1

Interacting Protein

HAT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HAT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HAT1.
MEOX2; vpr; TCF4; REL; RBBP4; TNFAIP1; HIST1H3D