Recombinant Human HAT1 Protein, GST-tagged

• Cat.No.: HAT1-4586H
• Product Overview: Human HAT1 full-length ORF ( AAH63003, 1 a.a. - 334 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a type B histone acetyltransferase (HAT) that is involved in the rapid acetylation of newly synthesized cytoplasmic histones, which are in turn imported into the nucleus for de novo deposition onto nascent DNA chains. Histone acetylation, particularly of histone H4, plays an important role in replication-dependent chromatin assembly. Specifically, this HAT can acetylate soluble but not nucleosomal histone H4 at lysines 5 and 12, and to a lesser degree, histone H2A at lysine 5. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 62.48 kDa
• AA Sequence: MFRVEYASKVDENFDCVEADDVEGK IRQIIPPGFCTNTNDFLSLLEKEVD FKPFGTLLHTYSVLSPTGGENFTFQ IYKADMTCRGFREYHERLQTFLMWF IETASFIDVDDERWHYFLVFEKYNK DGATLFATVGYMTVYNYYVYPDKTR PRVSQMLILTPFQGQGHGAQLLETV HRYYTEFPTVLDITAEDPSKSYVKL RDFVLVKLCQDLPCFSREKLMQGFN EDMAIEAQQKFKINKQHARRVYEIL RLLVTDMSDAEQYRSYRLDIKRRLI SPYKKKQRDLAKMRKCLRPEELTNQ MNQIEISMQHEQLEESFQELVEDYR RVIERLAQE
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -8 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: HAT1 histone acetyltransferase 1 [ Homo sapiens ]
• Official Symbol: HAT1
• Synonyms: HAT1; histone acetyltransferase 1; histone acetyltransferase type B catalytic subunit; KAT1
• Gene ID: 8520
• mRNA Refseq: NM_003642
• Protein Refseq: NP_003633
• MIM: 603053
• UniProt ID: O14929