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HAVCR2

  • Official Full Name

    hepatitis A virus cellular receptor 2

  • Overview

    Tim-3 is a transmembrane protein also known as T cell immunoglobulin and musin domain containing protein-3. Tim-3 is expressed at high levels on Th1 lymphocytes and CD11b<sup>+</sup>macrophages. Tim-3 has also been shown to exist as a soluble protein. Cel
  • Synonyms

    HAVCR2; hepatitis A virus cellular receptor 2; hepatitis A virus cellular receptor 2 homolog; TIM-3; TIMD-3; HAVcr-2; T-cell membrane protein 3; T cell immunoglobulin mucin-3; T-cell immunoglobulin and mucin domain-containing protein 3; tim3;

  • Recombinant Proteins
  • GMP Proteins
  • Antibody
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Canine
  • Cynomolgus
  • Cynomolgus monkey
  • Cynomolgus Monkey
  • Human
  • Monkey
  • Mouse
  • CHO
  • CHO cells
  • E.coli
  • HEK293
  • HEK293F
  • Human Cell
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian cells
  • NS0
  • Rabbit
  • Wheat Germ
  • Yeast
  • C
  • Fc
  • His
  • hFc
  • mFc
  • 6×His
  • DDK|His
  • Fc Chimera
  • Fc|His
  • Avi
  • His(C
  • ter)
  • GST
  • HIgG
  • hIgG
  • His (Fc)
  • His|Avi
  • human|IgG1|Fc
  • N/A
  • N
  • Strep
  • T7|His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HAVCR2-217H Active Recombinant Human HAVCR2, MIgG2a Fc-tagged CHO Fc
Human HAVCR2-515H Active Recombinant Human HAVCR2 Protein, His-tagged CHO His
Human HAVCR2-219H Active Recombinant Human HAVCR2, HIgG1 Fc-tagged CHO Fc
Human HAVCR2-3166H Active Recombinant Human HAVCR2, His tagged HEK293 His Met1-Arg200
Human HAVCR2-704H Active Recombinant Human HAVCR2, Fc-tagged, Biotinylated Human Cell Fc
Human HAVCR2-218H Active Recombinant Human Hepatitis A Virus Cellular Receptor 2, HIgG1 Fc-tagged CHO Fc
Human HAVCR2-514H Active Recombinant Human HAVCR2 Protein, Fc-tagged CHO Fc
Human HAVCR2-051H Active Recombinant Human HAVCR2 protein, His/Avi-tagged, Biotinylated CHO cells His/Avi Ser22-Arg200
Human HAVCR2-3272H Active Recombinant Human HAVCR2 protein(Met1-Arg200), His-tagged, Biotinylated HEK293 C-His Met1-Arg200
Human HAVCR2-706H Active Recombinant Human HAVCR2(Ser22-Arg200) Protein, C-Fc-Avi-tagged, Biotinylated HEK293 Fc-Avi
Human HAVCR2-440H Recombinant Human HAVCR2 Protein, Fc/His-tagged HEK293 Fc/His
Human HAVCR2-513H Recombinant Human HAVCR2, Fc-tagged CHO Fc
Human HAVCR2-7093H Recombinant Human HAVCR2, His-tagged E.coli His 22-202aa
Human HAVCR2-878H Recombinant Human HAVCR2 protein, Strep-tagged HEK293 Strep 179
Human HAVCR2-877H Recombinant Human HAVCR2, Fc-His tagged Human Cell Fc/His
Human HAVCR2-876H Recombinant Human HAVCR2 protein, Fc-tagged HEK293 human/IgG1/Fc 179
Human HAVCR2-4591H Recombinant Human HAVCR2 Protein, GST-tagged Wheat Germ GST
Human HAVCR2-439H Recombinant Human HAVCR2 Protein, DDK/His-tagged HEK293 DDK/His
Human HAVCR2-175H Recombinant Human HAVCR2 protein, T7/His-tagged E.coli T7/His
Human HAVCR2-1454H Recombinant Human HAVCR2 Protein (Ser22-Arg200), N-His tagged E.coli N-His Ser22-Arg200
Human HAVCR2-2023H Recombinant Human HAVCR2 Protein, His-tagged HEK293 His Ser22-Arg200
Human HAVCR2-367H Active Recombinant Human HAVCR2 protein, mFc-tagged HEK293 mFc Ser 22 - Arg 200
Human HAVCR2-5404H Recombinant Human HAVCR2 Protein (Ser22-Arg200), C-Fc and His tagged Mammalian cells C-Fc and His Ser22-Arg200
Human HAVCR2-0764H Active Recombinant Human HAVCR2 protein, Fc-tagged HEK293 Fc Ser22-Arg200
Human HAVCR2-371H Recombinant Human HAVCR2 protein, Fc-tagged HEK293 human/IgG1/Fc 121
Human HAVCR2-2670H Recombinant Human HAVCR2 protein, His-tagged E.coli His 143 - 301 aa
Human HAVCR2-705H Active Recombinant Human HAVCR2 Protein, His-Avi-tagged, Biotinylated HEK293 His/Avi
Human HAVCR2-3019H Recombinant Human HAVCR2 protein, His-tagged E.coli His 22-202aa
Human HAVCR2-3166HAF555 Recombinant Human HAVCR2 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His 190
Human HAVCR2-3166HAF488 Recombinant Human HAVCR2 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His 190
Human HAVCR2-023HG Active GMP Recombinant Human HAVCR2 protein, Fc-tagged HEK293 Fc DNA sequence encoding Human TIM3(NCBI Reference Sequence: NP_116171.3) was expressed with Fc tag at the C-terminal.
Human HAVCR2-877HAF488 Recombinant Human HAVCR2 Protein, Fc/His-tagged, Alexa Fluor 488 conjugated HEK293 Fc/His 426
Human HAVCR2-3166HAF647 Recombinant Human HAVCR2 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His 190
Human HAVCR2-5025H Recombinant Human HAVCR2 protein, hFc-tagged HEK293 hFc 20-200aa
Human HAVCR2-3166HB Recombinant Human HAVCR2 protein, His-tagged, Biotinylated HEK293 His
Human HAVCR2-5422H Recombinant Human HAVCR2 protein, His-tagged Yeast His 22-202aa
Human HAVCR2-3166HF Recombinant Human HAVCR2 Protein, His-tagged, FITC conjugated HEK293 His 190
Human HAVCR2-877HAF647 Recombinant Human HAVCR2 Protein, Fc/His-tagged, Alexa Fluor 647 conjugated HEK293 Fc/His 426
Human HAVCR2-877HAF555 Recombinant Human HAVCR2 Protein, Fc/His-tagged, Alexa Fluor 555 conjugated HEK293 Fc/His 426
Human HAVCR2-110H Recombinant Human HAVCR2 Protein (ECD), Fc-His-tagged(C-ter) HEK293 Fc-His(C-ter) Ser22-Arg200
Human HAVCR2-877HF Recombinant Human HAVCR2 Protein, Fc/His-tagged, FITC conjugated HEK293 Fc/His 426
Human HAVCR2-731H Recombinant Human HAVCR2 Protein (Ser22-Gly202), C-mFc and 6×His-tagged HEK293 C-mFc and 6×His Ser22-Gly202
Human HAVCR2-956H Recombinant Human HAVCR2 Protein, His-tagged HEK293F N-His Ser22-Gly202
Human HAVCR2-736H Recombinant Human HAVCR2 Protein, Strep-tagged HEK293 Strep 301
Human HAVCR2-3488HF Recombinant Full Length Human HAVCR2 Protein, GST-tagged In Vitro Cell Free System GST 142 amino acids
Human HAVCR2-3637H Recombinant Human HAVCR2 Protein (Met1-Arg200), C-His tagged Mammalian cells C-His Met1-Arg200
Human HAVCR2-111H Recombinant Human HAVCR2 Protein (ECD), His-tagged(C-ter) HEK293 His(C-ter) Ser22-Arg200
Human HAVCR2-737H Recombinant Human HAVCR2 Protein HEK293 301
Human HAVCR2-01H Active Recombinant Human HAVCR2 Protein, Fc-Tagged NS0 Fc
Human HAVCR2-5405H Recombinant Human HAVCR2 Protein (Ser22-Arg200), C-His tagged Mammalian cells C-His Ser22-Arg200
Human HAVCR2-02H Recombinant Human HAVCR2 Protein, hIgG-His-Tagged Insect Cell HIgG/His 423aa
Human CAB11553RH Rabbit Anti-Human TIMD3 / HAVCR2 Monoclonal Antibody Rabbit N/A
Human HAVCR2-149H Recombinant Human HAVCR2 Protein, His-tagged E.coli His
Human HAVCR2-455H Recombinant Human HAVCR2 Protein, Fc-tagged HEK293 Fc 301
Human HAVCR2-2610H Active Recombinant Human HAVCR2 protein, His-tagged HEK293 His Ser22-Arg200
Human HAVCR2-735H Recombinant Human HAVCR2 Protein, Fc-tagged HEK293 Fc 301
Human HAVCR2-1246H Active Recombinant Human HAVCR2 protein, hFc&His-tagged HEK293 hFc&His Ser22-Arg200
Mouse HAVCR2-211M Active Recombinant Mouse Hepatitis A Virus Cellular Receptor 2, MIgG2a Fc-tagged CHO Fc
Mouse Havcr2-397M Active Recombinant Mouse Havcr2, Fc Chimera Mammalian cells Fc Chimera
Mouse HAVCR2-319M Recombinant Mouse Havcr2, Fc tagged Human Cell His
Mouse HAVCR2-529M Recombinant Mouse Havcr2, His tagged Human Cell His
Mouse HAVCR2-995MCL Recombinant Mouse HAVCR2 cell lysate Human Cell N/A
Mouse HAVCR2-738M Recombinant Mouse HAVCR2 Protein HEK293 281
Mouse Havcr2-03M Recombinant Mouse Havcr2 Protein, hIgG-His-tagged HEK293 hIgG-His
Mouse Havcr2-112M Recombinant Mouse HAVCR2 Protein (ECD), Fc-His-tagged(C-ter) HEK293 Fc-His(C-ter) Arg20-Arg191
Mouse Havcr2-113M Recombinant Mouse HAVCR2 Protein (ECD), His-tagged(C-ter) HEK293 His(C-ter) Arg20-Arg191
Mouse HAVCR2-739M Recombinant Mouse HAVCR2 Protein, Fc-tagged HEK293 Fc 281
Mouse HAVCR2-319MF Recombinant Mouse Havcr2 Protein, Fc-tagged, FITC conjugated HEK293 Fc 411
Mouse Havcr2-138M Recombinant Mouse Havcr2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HAVCR2-0762M Recombinant Mouse HAVCR2 protein, His-tagged HEK293 His Arg20-Arg191
Mouse HAVCR2-319MAF488 Recombinant Mouse Havcr2 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 411
Mouse HAVCR2-529MF Recombinant Mouse Havcr2 Protein, His-tagged, FITC conjugated HEK293 His 181
Mouse HAVCR2-0763M Recombinant Mouse HAVCR2 protein, Fc-tagged HEK293 Fc Arg20-Arg191
Mouse HAVCR2-319MAF647 Recombinant Mouse Havcr2 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 411
Mouse HAVCR2-529MAF488 Recombinant Mouse Havcr2 Protein, His-tagged, Alexa Fluor 488 conjugated HEK293 His 181
Mouse HAVCR2-529MAF647 Recombinant Mouse Havcr2 Protein, His-tagged, Alexa Fluor 647 conjugated HEK293 His 181
Mouse HAVCR2-319MAF555 Recombinant Mouse Havcr2 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 411
Mouse HAVCR2-529MAF555 Recombinant Mouse Havcr2 Protein, His-tagged, Alexa Fluor 555 conjugated HEK293 His 181
Mouse Havcr2-138M-B Recombinant Mouse Havcr2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Havcr2-5715M Recombinant Mouse Havcr2 Protein (Leu22-Ala193), C-His tagged Mammalian cells C-His Leu22-Ala193
Mouse Havcr2-6822M Recombinant Mouse Havcr2 Protein (Arg20-Arg191), C-Fc tagged Mammalian cells C-Fc Arg20-Arg191
Mouse Havcr2-6823M Recombinant Mouse Havcr2 Protein (Arg20-Arg191), C-His tagged Mammalian cells C-His Arg20-Arg191
Monkey HAVCR2-213CF Recombinant Monkey HAVCR2 Protein, Fc-tagged, FITC conjugated HEK293 Fc Met1-Arg201, 418
Monkey HAVCR2-213CAF647 Recombinant Monkey HAVCR2 Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc Met1-Arg201, 418
Monkey HAVCR2-213CAF488 Recombinant Monkey HAVCR2 Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc Met1-Arg201, 418
Monkey HAVCR2-213CAF555 Recombinant Monkey HAVCR2 Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc Met1-Arg201, 418
Canine HAVCR2-0760C Recombinant Canine HAVCR2 protein, His-tagged HEK293 His Ala24-Arg189
Cynomolgus HAVCR2-213C Recombinant Cynomolgus HAVCR2 protein(Met1-Arg201), hFc-tagged HEK293 C-hFc Met1-Arg201
Cynomolgus HAVCR2-0761C Active Recombinant Cynomolgus HAVCR2 protein, Fc-tagged HEK293 Fc Ser22-Arg201
Cynomolgus HAVCR2-682C Active Recombinant Cynomolgus HAVCR2 protein, His-tagged HEK293 His Ser 22 - Arg 201
Cynomolgus Monkey HAVCR2-540C Active Recombinant Cynomolgus Monkey HAVCR2, Fc Chimera HEK293 Fc Chimera
Cynomolgus Monkey HAVCR2-001CCL Recombinant Cynomolgus HAVCR2 cell lysate Human Cell N/A
Cynomolgus monkey HAVCR2-734C Recombinant Cynomolgus monkey HAVCR2 Protein, Fc-tagged HEK293 Fc 302
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HAVCR2 Related Articles
  • HAVCR2 Related Research Area

HAVCR2 involved in several pathways and played different roles in them. We selected most pathways HAVCR2 participated on our site, such as Cytokine Signaling in Immune system, Immune System, Interleukin-2 signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with HAVCR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine Signaling in Immune systemKPNA5;LAMTOR2;IFI6;EDAR;ARIH1L;LGALS9;NUP50;EGR1;SPTBN1
Immune SystemLILRA2;PJA2;ATP6V1G3;EGR1;CISH;TXNIP;AP1G1;CLEC2H;PPAPDC1B
Interleukin-2 signalingLGALS9;HAVCR2
Signaling by InterleukinsCASPBL;HAVCR2;SOCS3A;CASPB;LGALS9;IL1RN

HAVCR2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by HAVCR2 itself. We selected most functions HAVCR2 had, and list some proteins which have the same functions with HAVCR2. You can find most of the proteins on our site.

Function Related Protein

HAVCR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HAVCR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HAVCR2.

Markwick, LJL; Riva, A; et al. Blockade of PD1 and TIM3 Restores Innate and Adaptive Immunity in Patients With Acute Alcoholic Hepatitis. GASTROENTEROLOGY 148:590-+(2015).
Sabahi, A; Uprichard, SL; et al. Unexpected Structural Features of the Hepatitis C Virus Envelope Protein 2 Ectodomain. JOURNAL OF VIROLOGY 88:10280-10288(2014).
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