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Tim-3 is a transmembrane protein also known as T cell immunoglobulin and musin domain containing protein-3. Tim-3 is expressed at high levels on Th1 lymphocytes and CD11b<sup>+</sup>macrophages. Tim-3 has also been shown to exist as a soluble protein. Cel
Synonyms
HAVCR2;hepatitis A virus cellular receptor 2;hepatitis A virus cellular receptor 2 homolog;TIM-3;TIMD-3;HAVcr-2;T-cell membrane protein 3;T cell immunoglobulin mucin-3;T-cell immunoglobulin and mucin domain-containing protein 3;tim3
HAVCR2 involved in several pathways and played different roles in them. We selected most pathways HAVCR2 participated on our site, such as Cytokine Signaling in Immune system,Immune System,Interleukin-2 signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with HAVCR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
HAVCR2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by HAVCR2 itself. We selected most functions HAVCR2 had, and list some proteins which have the same functions with HAVCR2. You can find most of the proteins on our site.
Function
Related Protein
Interacting Protein
HAVCR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HAVCR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of HAVCR2.
Markwick, LJL; Riva, A; et al. Blockade of PD1 and TIM3 Restores Innate and Adaptive Immunity in Patients With Acute Alcoholic Hepatitis. GASTROENTEROLOGY 148:590-+(2015).
Sabahi, A; Uprichard, SL; et al. Unexpected Structural Features of the Hepatitis C Virus Envelope Protein 2 Ectodomain. JOURNAL OF VIROLOGY 88:10280-10288(2014).
