HDAC9

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HDAC9

Official Full Name histone deacetylase 9
Background Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
Synonyms HDAC9; histone deacetylase 9; HD7; HDAC; HDAC7B; KIAA0744; MITR; histone deacetylase 7B; histone deacetylase 4/5-related protein; MEF-2 interacting transcription repressor (MITR) protein; HD9; HD7b; HDRP; HDAC7; HDAC9B; HDAC9FL; DKFZp779K1053
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human HDAC9-1303H Recombinant Human HDAC9 Protein (814-1011 aa), His-tagged E.coli His
    Human HDAC9-3234H Recombinant Human HDAC9 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Hdac9-3371M Recombinant Mouse Hdac9 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human HDAC9-42H Recombinant Human HDAC9 Protein, His-tagged Insect Cell His
    Human HDAC9-1372H Recombinant Human HDAC9 protein, His & T7-tagged E.coli His/T7
    Human HDAC9-1596H Recombinant Human Histone Deacetylase 9, His-tagged Sf9 Insect Cell GST
    Human HDAC9-28444TH Recombinant Human HDAC9, His-tagged His
    Human HDAC9-400H Recombinant Human Histone Deacetylase 9, GST-tagged Insect Cell GST
    Human HDAC9-4652H Recombinant Human HDAC9 Protein, GST-tagged Wheat Germ GST
    Human HDAC9-5601HCL Recombinant Human HDAC9 293 Cell Lysate HEK293 N/A
    Human HDAC9-798H Recombinant Human HDAC9 Mammalian Cell His
    Chicken HDAC9-2665C Recombinant Chicken HDAC9 Mammalian Cell His
    Kit-1745 HDAC9 Fluorogenic Assay Kit N/A

    HDAC9 involved in several pathways and played different roles in them. We selected most pathways HDAC9 participated on our site, such as Alcoholism, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HDAC9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Alcoholism HDAC10; HDAC7A; H3F3B; HIST1H2BB; BRAF; HIST1H3H; ATF6B; GM14477; SHC2; CREB3L1
    Viral carcinogenesis HIST1H4H; HIST1H4K; HIST1H2BE; HIST1H4I; CCNE2; ACTN1; TTC6; RANBP1; HIST1H4A; PXN

    HDAC9 has several biochemical functions, for example, NAD-dependent histone deacetylase activity (H3-K14 specific), histone deacetylase activity, NOT histone deacetylase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HDAC9 itself. We selected most functions HDAC9 had, and list some proteins which have the same functions with HDAC9. You can find most of the proteins on our site.

    Function Related Protein
    NAD-dependent histone deacetylase activity (H3-K14 specific) HDAC10; HDAC9B; HDAC6; HDAC7; HDAC9; HDAC2; HDAC1; HDAC8; HDAC11; HDAC3
    histone deacetylase activity SIRT2; HDAC6; HDAC3; HDAC2; ATXN3L; HDAC9B; HDAC5; HDAC8; SIRT1; HDAC9
    NOT histone deacetylase activity HDAC9
    histone deacetylase binding NKX2-5; KAT2A; HES1; USF1; ZNHIT1; TCF21; CCND1; RAD9A; NCOR1; PKN1
    metal ion binding ZFP161; INO80B; BTK; ACSM5; INPP5B; ZFP579; ELP3; PRICKLE2B; ACVR1C; PAPD7
    protein binding IGFL1; LIPT2; SEC14L4; DAPK1; TEF; PTRH1; MRPL10; FABP5; TGM1; MAGOH
    protein deacetylase activity SIRT1; SIN3A; HDAC1; HDAC5; SIRT2; HDAC4; HDAC2; HDAC10; HDAC9; HDAC3
    protein kinase C binding GNB2L1; ADD3; PICK1; ADAM9; PARD6A; PRKCSH; FLNA; AVPR1A; TIRAP; AKT2
    repressing transcription factor binding GMNN; RUNX2; TLE4; RELA; TBP; HMGB1; SRI; MAGEA2B; HDAC9; HDAC7
    transcription corepressor activity PIAS1; SETD8; SSX2; THRB; FEV; HOXC6; RUNX1T1; SOD3; ENO1; PRMT5
    transcription factor binding MDFI; AIP; SIRT2; CTBP1; TBL1X; NFATC3; TLE1; PPRC1; TP73; GTF2F1

    HDAC9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HDAC9 here. Most of them are supplied by our site. Hope this information will be useful for your research of HDAC9.

    BCL6; USF1; NCOR1; ETV6; FOXP3; FOXP3; YWHAE; MEF2C; tkt1; WNK1; ZC3H11A; TOP1; TPR; RCC1; MKI67; NOP2; ADAR

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