HMGA1
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Official Full Name
high mobility group AT-hook 1
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Synonyms
HMGA1; high mobility group AT-hook 1; high mobility group (nonhistone chromosomal) protein isoforms I and Y , HMGIY; high mobility group protein HMG-I/HMG-Y; HMG-I(Y); high mobility group protein R; high mobility group protein A1; nonhistone chromosomal h;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
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- Rhesus Macaque
- E. coli
- E.coli
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- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- HMGA1 Related Articles
HMGA1 involved in several pathways and played different roles in them. We selected most pathways HMGA1 participated on our site, such as 2-LTR circle formation, APOBEC3G mediated resistance to HIV-1 infection, Adipogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HMGA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| 2-LTR circle formation | PSIP1;HMGA1;BANF1;gag |
| APOBEC3G mediated resistance to HIV-1 infection | PSIP1;HMGA1;BANF1;APOBEC3G;gag;PPIA |
| Adipogenesis | KCNA3;KLF5;MBNL1;DDIT3;CEBPA;NR2F1;GDF10;STIL;CREB1 |
| Autointegration results in viral DNA circles | PSIP1;gag;BANF1;HMGA1 |
| Cellular Senescence | RBBP4;CABIN1;KDM6B;CBX6A;CBX8;H3F3D;SCMH1;CEBPB;RING1 |
| Cellular responses to stress | EEF1A1;ULK1A;RRAGB;DNAJC7;WDR45L;RB1CC1;TXN;H3F3D;EED |
| DNA Damage/Telomere Stress Induced Senescence | POT1A;RAD50;HMGA1;HIRA;TERF1;ASF1A;HMGA1-RS1;ACD;HTATIP |
| Disease | TCEB3;CTBP1;CCDC167;MMADHC;AMN;EEF2;VPS37A;ELL;AP2A2 |
HMGA1 has several biochemical functions, for example, 5-deoxyribose-5-phosphate lyase activity, AT DNA binding, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HMGA1 itself. We selected most functions HMGA1 had, and list some proteins which have the same functions with HMGA1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 5-deoxyribose-5-phosphate lyase activity | HMGA1-RS1;HMGA2;XRCC6;HMGA1 |
| AT DNA binding | HMGA2;HMGA1;MEF2C;POU3F4;CRIP1 |
| DNA binding | POLD2;TSHZ3;HIST4H4;ZNF167;ZNF574;PUF60B;ZNF70;NKX3-1;HIST1H3D |
| DNA-(apurinic or apyrimidinic site) lyase activity | NEIL3;NEIL2;HMGA2;NTHL1;APEX2;HMGA1;HMGA1-RS1;APEX1;HMGA1B |
| chromatin binding | PCGF2;SMC3;GATA2;TGIF1;CBX7;KAT2B;PRKCBP1L;SNAI2;SETD7 |
| enzyme binding | CFTR;RFC5;TRIO;CYP2E1;CASP2;PPP1R3B;TSPAN5;TSPYL1;NOP14 |
| ligand-dependent nuclear receptor transcription coactivator activity | NCOA3;RBM14;WDR77;PPARG;MED1;PRKCBB;ACTN1;ZCCHC18;USP22 |
| peroxisome proliferator activated receptor binding | CREBBP;ASXL1;PPARGC1A;ASXL2;NFATC4;EP300;PRMT2;MED1;IKBKG |
| protein binding | EEF1E1;NOL12;DOHH;TMEM199;CD40;ORAI3;WBSCR27;MAP3K7IP3;BCL2L11 |
| retinoic acid receptor binding | ASXL1;HMGA1;AASS;MED1;MED25;PRAMEF2;SNW1;RXRA;CNOT1 |
| retinoid X receptor binding | HMGA1-RS1;VDR;NR0B2;NSD1;RARG;NR1H2;MED25;FUS;RARB |
| transcription factor activity, sequence-specific DNA binding | FOXE1;RUNX2B;ZFY2;MNT;RELA;REST;SOX9;CREBZF;JUNBA |
| transcription factor binding | FOXC1;SRY;TRP53;PRKDC;DOT1L;AGTR2;RBL1;E2F2;HDAC8 |
| transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding | HMGA1;PROP1;TARDBP;SIX3;NFE2L2;HOXB5;ARID3B;FUBP1;HCFC1 |
HMGA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HMGA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HMGA1.
SP1; CEBPB; il2ra_human_gene; il2ra_human_+3317/+3478_dna-probe; Stag2; HSP90AB1; HTT; EWSR1; Kifc5b; ssdna_dadts
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