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HMGA1

  • Official Full Name

    high mobility group AT-hook 1

  • Synonyms

    HMGA1; high mobility group AT-hook 1; high mobility group (nonhistone chromosomal) protein isoforms I and Y , HMGIY; high mobility group protein HMG-I/HMG-Y; HMG-I(Y); high mobility group protein R; high mobility group protein A1; nonhistone chromosomal h;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HMGA1-4863H Recombinant Human HMGA1 Protein, GST-tagged Wheat Germ GST
Human HMGA1-3597H Recombinant Human HMGA1, His-tagged E.coli His
Human HMGA1-5479HCL Recombinant Human HMGA1 293 Cell Lysate HEK293 N/A
Human HMGA1-5480HCL Recombinant Human HMGA1 293 Cell Lysate HEK293 N/A
Human HMGA1-1690H Recombinant Human HMGA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HMGA1-4435H Recombinant Human HMGA1 Protein, His-tagged E. coli His
Human HMGA1-5225H Recombinant Human HMGA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HMGA1-4437H Recombinant Human HMGA1 Protein, His-tagged E. coli His
Human HMGA1-5529H Recombinant Human HMGA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HMGA1-827H Recombinant Human HMGA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HMGA1-3642HF Recombinant Full Length Human HMGA1 Protein, GST-tagged In Vitro Cell Free System GST 96 amino acids
Human HMGA1-5806H Recombinant Human HMGA1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HMGA1-3081H Recombinant Human HMGA1 Protein (Glu3-Gln107), His tagged E.coli His Glu3-Gln107
Mouse HMGA1-7725M Recombinant Mouse HMGA1 Protein Mammalian Cell His
Mouse Hmga1-1138M Recombinant Mouse Hmga1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse HMGA1-4234M Recombinant Mouse HMGA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Hmga1-174M Recombinant Mouse Hmga1 Protein, His-tagged E.coli His Met1~Gln107
Mouse HMGA1-4234M-B Recombinant Mouse HMGA1 Protein Pre-coupled Magnetic Beads HEK293
Rat HMGA1-2865R Recombinant Rat HMGA1 Protein Mammalian Cell His
Rat Hmga1-175R Recombinant Rat Hmga1 Protein, His-tagged E.coli His Met1~Gln107
Rat HMGA1-2520R Recombinant Rat HMGA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat HMGA1-2520R-B Recombinant Rat HMGA1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque HMGA1-2107R Recombinant Rhesus monkey HMGA1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque HMGA1-1928R-B Recombinant Rhesus Macaque HMGA1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque HMGA1-1928R Recombinant Rhesus Macaque HMGA1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken HMGA1-5939C Recombinant Chicken HMGA1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HMGA1 Related Articles

HMGA1 involved in several pathways and played different roles in them. We selected most pathways HMGA1 participated on our site, such as 2-LTR circle formation, APOBEC3G mediated resistance to HIV-1 infection, Adipogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with HMGA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
2-LTR circle formationgag;HMGA1;BANF1;PSIP1
APOBEC3G mediated resistance to HIV-1 infectionBANF1;APOBEC3G;gag;PPIA;PSIP1;HMGA1
AdipogenesisMEF2B;DVL1;EGR2B;CYP26A1;CFD;BSCL2;HMGA1;KCNA3;NCOA2
Autointegration results in viral DNA circlesBANF1;gag;PSIP1;HMGA1
Cellular SenescenceTERF1;CBX8;CDKN2B;PHC1;POT1A;BMI1A;EP400;AGO3;SUZ12A
Cellular responses to stressDYNLL2B;EGLN3;CDKN2C;CBX6A;CBX4;PHC2;RRAGA;DNAJB6;EGLN1B
DNA Damage/Telomere Stress Induced SenescenceASF1A;TERF1;UBN1;HMGA1;HTATIP;HIST1H1B;TINF2;ACD;TERF2
DiseaseANTXR2;EPM2A;GPC6;HEY2;CHMP4B;MIB1;OPN1SW;LTF;OPN1MW

HMGA1 has several biochemical functions, for example, 5-deoxyribose-5-phosphate lyase activity, AT DNA binding, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HMGA1 itself. We selected most functions HMGA1 had, and list some proteins which have the same functions with HMGA1. You can find most of the proteins on our site.

Function Related Protein
5-deoxyribose-5-phosphate lyase activityHMGA1-RS1;HMGA2;HMGA1;XRCC6
AT DNA bindingPOU3F4;HMGA1;HMGA2;MEF2C;CRIP1
DNA bindingFOXQ2;FLI1B;WBP7;RAG2;ZNF45;NR4A2;XRN1;LYL1;ZBED2
DNA-(apurinic or apyrimidinic site) lyase activityNEIL3;HMGA1;ALKBH1;HMGA2;NEIL1;APEX2;NEIL2;APLF;NTHL1
chromatin bindingSP140L;SMARCD1;ADNP;ZMYND11;TCF7L1B;RING1;CDCA5;EZH1;SATB1
enzyme bindingKMT2E;USF1;APOA5;UGT1A6B;CALU;Il6ra;EGFR;GSTM7;BRCA1
ligand-dependent nuclear receptor transcription coactivator activityLRP2BP;PRKCB;NCOA1;SLC30A9;PRKCBB;MED1;ZCCHC12;FGF2;HELZ2
peroxisome proliferator activated receptor bindingNR0B2;MED1;HMGA1-RS1;ASXL1;HMGA1;IKBKG;PPARGC1A;CREBBP;EP300
protein bindingVEZT;MFAP4;BDKRB2;TRIM67;GPS1;ANLN;KCNB1;RXRB;FRAG1
retinoic acid receptor bindingNSD1;PRAMEF10;MED1;AASS;RXRA;SNW1;ACTN4;MED25;PRAMEF1
retinoid X receptor bindingNCOR1;HMGA1;RARB;FUS;HMGA1-RS1;VDR;NRIP1;MED25;NR0B2
transcription factor activity, sequence-specific DNA bindingRHOXF1;SALL3;ZSCAN20;RORA;GATA2;FOXI3B;TCF25;ZNF317;ZFP12
transcription factor bindingPPID;MYC;HEY2;FOS;ZEB1;KAT8;PSMD4;MAFB;KLF5
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific bindingRELA;PBX3;FUBP1;SIX3;CDX1;SUB1;ZEB2;NFE2L2;BACH1

HMGA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HMGA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of HMGA1.

SP1; CEBPB; il2ra_human_gene; il2ra_human_+3317/+3478_dna-probe; Stag2; HSP90AB1; HTT; EWSR1; Kifc5b; ssdna_dadts

Chieffi, P; Chieffi, S; et al. Molecular biomarkers as potential targets for therapeutic strategies in human testicular germ cell tumors: An overview. JOURNAL OF CELLULAR PHYSIOLOGY 228:1641-1646(2013).
Chieffi, P; et al. New Prognostic Markers and Potential Therapeutic Targets in Human Testicular Germ Cell Tumors. CURRENT MEDICINAL CHEMISTRY 18:5033-5040(2011).
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