hrh3
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  • Official Full Name
  • histamine receptor H3
  • Background
  • Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
  • Synonyms
  • HRH3; histamine receptor H3; histamine H3 receptor; GPCR97; H3R; G protein-coupled receptor 97; G-protein coupled receptor 97; HH3R
Cat.#:HRH3-5037HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HRH3 Protein, GST-tagged
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Cat.#:HRH3-702HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human HRH3
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Cat.#:HRH3-7850MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse HRH3 Protein
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Cat.#:HRH3-2144RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey HRH3 Protein, His-tagged
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Cat.#:HRH3-3136ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish HRH3
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Cat.#:Kit-1075Tag:
Source (Host):Species:
Product nameChitotriosidase Activity Assay Kit (Fluorometric)
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Cat.#:Kit-1346Tag:
Source (Host):Species:
Product namecAMP HRH3 CHO-K1 GPCR Assay Kit
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Cat.#:Kit-1347Tag:
Source (Host):Species:
Product nameHRH3 CHO-K1 β-Arrestin GPCR Assay Kit
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Cat.#:Kit-0970Tag:
Source (Host):Species:
Product nameTR-FRET PPAR gamma Competitive Binding Assay Kit, goat
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Cat.#:CSC-RG0528Tag:
Source (Host):Species:Human
Product nameHuman HRH3/Gi/Go Stable Cell Line-CHO
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Involved Pathway

HRH3 involved in several pathways and played different roles in them. We selected most pathways HRH3 participated on our site, such as Amine ligand-binding receptors, Class A/1 (Rhodopsin-like receptors), G alpha (i) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with HRH3 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Amine ligand-binding receptors
ADRB2; ADRB3; CHRM1; DRD1; ADRB1; DRD5; DRD3; ADRa1A; ADRA2C; ADRA2B
Class A/1 (Rhodopsin-like receptors)
SAA1; EDNRA; ADRB3; DRD5; INSL3; PMCH; CXCR6; LPAR2A; AMCF-II; PROKR1A
G alpha (i) signalling events
HEBP1; NMS; CHRM4; OPN1LW1; RGS10; NMUR1; SSTR2; PMCH; PENKA; FPR-RS4
GPCR downstream signaling
OXER1; GCGA; NPSR1; PROK1; LTB4R; CHRM1; RLN3A; GAL; GPR18; ADORA1
GPCR ligand binding
PENKA; PENK; CHRM5; ZFPM2B; DRD4; GPRC6A; GPR18; PNOC; S1PR3; OPN4.1
GPCRs, Class A Rhodopsin-like
OPN3; CCR8; GPR1; ADORA1; DRD3; GPR27; GPR68; FFAR3; GPR3; GPR50
Histamine receptors
HRH3
Monoamine Transport
TPH2; SYN1; TGFB1I1; DBH; FBXO32; SCAMP2; HRH3; UNC13B

Protein Function

HRH3 has several biochemical functions, for example, histamine binding, histamine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HRH3 itself. We selected most functions HRH3 had, and list some proteins which have the same functions with HRH3. You can find most of the proteins on our site.
Function
Related Protein
Function histamine binding
Related Protein HRH1; HRH3; HRH4
Function histamine receptor activity
Related Protein HRH4; HTR6; HRH1; HRH2; HRH3