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HRH3

  • Official Full Name

    histamine receptor H3

  • Overview

    Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
  • Synonyms

    HRH3; histamine receptor H3; histamine H3 receptor; GPCR97; H3R; G protein-coupled receptor 97; G-protein coupled receptor 97; HH3R;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Cavia porcellus (Guinea pig)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Zebrafish
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • Wheat Germ
  • GFP
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HRH3-702H Recombinant Human HRH3 Mammalian Cell His
Human HRH3-5037H Recombinant Human HRH3 Protein, GST-tagged Wheat Germ GST
Human HRH3-3123H Recombinant Human HRH3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HRH3-3123H-B Recombinant Human HRH3 Protein Pre-coupled Magnetic Beads HEK293
Human HRH3-0281H Recombinant Human HRH3 Full Length Transmembrane protein, His-tagged HEK293 His 1-445aa
Human HRH3-2945H Recombinant Human HRH3 Full Length Transmembrane protein, GFP-tagged HEK293 GFP 1-445aa
Human HRH3-2048H Recombinant Human HRH3 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Mouse HRH3-7850M Recombinant Mouse HRH3 Protein Mammalian Cell His
Mouse HRH3-4318M-B Recombinant Mouse HRH3 Protein Pre-coupled Magnetic Beads HEK293
Mouse HRH3-4318M Recombinant Mouse HRH3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cavia porcellus (Guinea pig) RFL19166CF Recombinant Full Length Guinea Pig Histamine H3 Receptor(Hrh3) Protein, His-Tagged E.coli expression system His Full Length (1-445)
Homo sapiens (Human) RFL32445HF Recombinant Full Length Human Histamine H3 Receptor(Hrh3) Protein, His-Tagged E.coli expression system His Full Length (1-445)
Mus musculus (Mouse) RFL5792MF Recombinant Full Length Mouse Histamine H3 Receptor(Hrh3) Protein, His-Tagged E.coli expression system His Full Length (1-445)
Rattus norvegicus (Rat) RFL5053RF Recombinant Full Length Rat Histamine H3 Receptor(Hrh3) Protein, His-Tagged E.coli expression system His Full Length (1-445)
Rhesus Macaque HRH3-2144R Recombinant Rhesus monkey HRH3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque HRH3-1965R-B Recombinant Rhesus Macaque HRH3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque HRH3-1965R Recombinant Rhesus Macaque HRH3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish HRH3-3136Z Recombinant Zebrafish HRH3 Mammalian Cell His
Kit-1346 cAMP HRH3 CHO-K1 GPCR Assay Kit N/A
Kit-0970 TR-FRET PPAR gamma Competitive Binding Assay Kit, goat N/A
Kit-1075 Chitotriosidase Activity Assay Kit (Fluorometric) N/A
Kit-1347 HRH3 CHO-K1 β-Arrestin GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

HRH3 involved in several pathways and played different roles in them. We selected most pathways HRH3 participated on our site, such as Amine ligand-binding receptors, Class A/1 (Rhodopsin-like receptors), G alpha (i) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with HRH3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Amine ligand-binding receptorsDRD5;ADRA2B;TAAR1;ADRB1;ADRB2;ADRA1D;CHRM1;DRD4;DRD3
Class A/1 (Rhodopsin-like receptors)OXGR1A.3;NPS;RGS1;GPR55;GPR68;CNR2;APLNR;HCRT;OPN1LW2
G alpha (i) signalling eventsCCR6;LPAR1;TAS2R7;CCR8;RGS20;GPR18;OXGR1;OXER1;CCR3
GPCR downstream signalingCCL19A.2;ANXA1B;PROKR1A;OR52B4;PNOC;EDNRA;RAMP1;CRHR1;PENKB
GPCR ligand bindingINSL3;PENKA;S1PR3;SCT;RLN3;EMR2;GPR55;TAC3;PYYA
GPCRs, Class A Rhodopsin-likeCCR1;FPR-RS4;RRH;HRH3;FPR-RS3;ADORA3;GPR39;OR3A4P;GPR18
Histamine receptors
Monoamine TransportDBH;FBXO32;TPH2;SCAMP2;TGFB1I1;UNC13B;HRH3;SYN1

HRH3 has several biochemical functions, for example, histamine binding, histamine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HRH3 itself. We selected most functions HRH3 had, and list some proteins which have the same functions with HRH3. You can find most of the proteins on our site.

Function Related Protein
histamine bindingHRH3;HRH1;HRH4
histamine receptor activityHRH2;HRH1;HRH4;HTR6;HRH3

HRH3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HRH3 here. Most of them are supplied by our site. Hope this information will be useful for your research of HRH3.

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