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HSD17B14

  • Official Full Name

    hydroxysteroid (17-beta) dehydrogenase 14

  • Overview

    17-beta-hydroxysteroid dehydrogenases, such as HSD17B14, are primarily involved in metabolism of steroids at the C17;position and also of other substrates, such as fatty acids, prostaglandins, and xenobiotics (Lukacik et al., 2007;(PubMed 17067289)).
  • Synonyms

    HSD17B14; hydroxysteroid (17-beta) dehydrogenase 14; dehydrogenase/reductase (SDR family) member 10 , DHRS10; 17-beta-hydroxysteroid dehydrogenase 14; retinal short chain dehydrogenase/reductase 3; retSDR3; SDR47C1; short chain dehydrogenase/reductase family 47C; member 1; 17 beta hydroxysteroid dehydrogenase 14; 17 beta hydroxysteroid dehydrogenase DHRS10; Dehydrogenase/reductase SDR family member 10; DHRS10; Retinal short chain dehydrogenase/reductase retSDR3; SDR3; 17-beta-HSD 14; 17-beta-hydroxysteroid dehydrogenase DHRS10; retinal short-chain dehydrogenase/reductase 3; dehydrogenase/reductase (SDR family) member 10; retinal short-chain dehydrogenase/reductase retSDR3; short chain dehydrogenase/reductase family 47C, member 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HSD17B14-644H Recombinant Human HSD17B14 Protein, His-tagged HEK293 His
Human HSD17B14-28397TH Recombinant Human HSD17B14, His-tagged E.coli His 270 amino acids
Human HSD17B14-2877H Recombinant Human HSD17B14, His-tagged E.coli His
Human HSD17B14-13957H Recombinant Human HSD17B14, His-tagged E.coli His 1-270a.a.
Human HSD17B14-5068H Recombinant Human HSD17B14 Protein, GST-tagged Wheat Germ GST
Human HSD17B14-470HCL Recombinant Human HSD17B14 cell lysate N/A
Human HSD17B14-3615H Recombinant Human HSD17B14 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HSD17B14-4751H Recombinant Human HSD17B14 protein, His-SUMO-tagged E.coli His-SUMO 1-270aa
Human HSD17B14-534HFL Recombinant Full Length Human HSD17B14 Protein, C-Flag-tagged Mammalian cells Flag
Human HSD17B14-1103H-B Recombinant Human HSD17B14 Protein Pre-coupled Magnetic Beads HEK293
Human HSD17B14-1103H Recombinant Human HSD17B14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human HSD17B14-3856HF Recombinant Full Length Human HSD17B14 Protein, GST-tagged In Vitro Cell Free System GST 270 amino acids
Human HSD17B14-2130H Recombinant Human HSD17B14 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Mouse Hsd17b14-3443M Recombinant Mouse Hsd17b14 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Zebrafish HSD17B14-960Z Recombinant Zebrafish HSD17B14 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HSD17B14 Related Articles

HSD17B14 involved in several pathways and played different roles in them. We selected most pathways HSD17B14 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HSD17B14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

HSD17B14 has several biochemical functions, for example, estradiol 17-beta-dehydrogenase activity, protein binding, testosterone 17-beta-dehydrogenase (NADP+) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HSD17B14 itself. We selected most functions HSD17B14 had, and list some proteins which have the same functions with HSD17B14. You can find most of the proteins on our site.

Function Related Protein
estradiol 17-beta-dehydrogenase activityHSD17B14;HSD17B7;HSD17B10;HSD17B12;HSD17B12A;RDH8;HSD17B2;H2-KE6;AKR1B15
protein bindingMED22;TNIP3;FGF13;OAS1A;FZR1;STRADA;SPRR3;TRMT61B;GTF2H3
testosterone 17-beta-dehydrogenase (NADP+) activityAKR1C3;AKR1C6;HSD17B3;HSD17B14

HSD17B14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSD17B14 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSD17B14.

WDYHV1; NUDT18; PHF1; MPG; CA8; DDIT3

Sivik, T; Vikingsson, S; et al. Expression Patterns of 17 beta-Hydroxysteroid Dehydrogenase 14 in Human Tissues. HORMONE AND METABOLIC RESEARCH 44:949-956(2012).
Sivik, T; Gunnarsson, C; et al. 17 beta-Hydroxysteroid Dehydrogenase Type 14 Is a Predictive Marker for Tamoxifen Response in Oestrogen Receptor Positive Breast Cancer. PLOS ONE 7:-(2012).
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