|Official Full Name||hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)|
|Background||NAD-dependent oxidoreductase with broad substrate specificity that shows both oxidative and reductive activity (in vitro). Has 17-beta-hydroxysteroid dehydrogenase activity towards various steroids (in vitro). Converts 5-alpha-androstan-3-alpha,17-beta-diol to androsterone and estradiol to estrone (in vitro). Has 3-alpha-hydroxysteroid dehydrogenase activity towards androsterone (in vitro). Has retinol dehydrogenase activity towards all-trans-retinol (in vitro). Can convert androsterone to epi-androsterone.|
|Synonyms||HSD17B6; hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse); HSE; RODH; SDR9C6; 17-beta-hydroxysteroid dehydrogenase type 6; 17-beta-HSD6; 17-beta-HSD 6; oxidoreductase; 3-alpha->beta-HSE; retinol dehydrogenase; 3-hydroxysteroid epimerase; 3-alpha->beta-hydroxysteroid epimerase; 3(alpha->beta)-hydroxysteroid epimerase; 3(alpha->beta)-hydroxysteroid epimerasel; oxidative 3-alpha hydroxysteroid dehydrogenase; oxidative 3-alpha-hydroxysteroid-dehydrogenase; short chain dehydrogenase/reductase family 9C, member 6; NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
HSD17B6 involved in several pathways and played different roles in them. We selected most pathways HSD17B6 participated on our site, such as Steroid hormone biosynthesis, Retinol metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSD17B6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Steroid hormone biosynthesis||AKR1D1; CYP3A7-CYP3AP1; COMTB; SULT2B1; UGT1A3; CYP2D9; UGT1A6B; UGT2A3; CYP2C70; CYP19A1B|
|Retinol metabolism||RDH10A; CYP2A12; SDR16C5A; CYP4A10; CYP2B19; AOX3; DGAT1A; CYP2C37; RPE65; CYP4A14|
|Metabolic pathways||GNE; COX8C; IDH3B; IDS; PLCH1; RPN2; AGXT; PNLIP; ALPI; GRHPRA|
HSD17B6 has several biochemical functions, for example, catalytic activity, electron carrier activity, estradiol 17-beta-dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HSD17B6 itself. We selected most functions HSD17B6 had, and list some proteins which have the same functions with HSD17B6. You can find most of the proteins on our site.
|catalytic activity||ACSM2; GLULC; PCXA; PPM1BB; SYN2B; ALPI.1; IMPDH1A; DIP2C; PPM1BA; AZIN1A|
|electron carrier activity||AOX3L1; AKR7A3; COX7A1; ACOX3; UGDH; FDX1B; TXNRD1; GCDHA; GRXCR1; COX7A2A|
|estradiol 17-beta-dehydrogenase activity||HSD17B1; RDH8A; HSD17B2; HSD17B11; HSD17B12; HSD17B10; RDH8; AKR1C6; HSD17B12A; HSD17B14|
|oxidoreductase activity||GFOD1; HSDL1; GCDHB; CYP2D26; ADOA; AIFM3; ADH8B; ADH1; APEX1; PHF2|
|retinol dehydrogenase activity||RDH8; HSD17B6; RDH1; DHRS7C; RDH11; SDR16C5; RDH12; DHRS3; SDR9C7; DHRS9|
|testosterone dehydrogenase (NAD+) activity||HSD17B8; HSD17B1; HSD17B6; AKR1C3; HSD17B2; H2-KE6; DHRS9|
HSD17B6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSD17B6 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSD17B6.