Recombinant Human HSD17B6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: HSD17B6-3703H
• Product Overview: HSD17B6 MS Standard C13 and N15-labeled recombinant protein (NP_003716) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family.
• Molecular Mass: 36 kDa
• AA Sequence: MWLYLAAFVGLYYLLHWYRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKGAEQLRGQTSDRLETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGRVAFFVGGYCVSKYGVEAFSDILRREIQHFGVKISIVEPGYFRTGMTNMTQSLERMKQSWKEAPKHIKETYGQQYFDALYNIMKEGLLNCSTNLNLVTDCMEHALTSVHPRTRYSAGWDAKFFFIPLSYLPTSLADYILTRSWPKPAQAVTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: HSD17B6 hydroxysteroid 17-beta dehydrogenase 6 [ Homo sapiens (human) ]
• Official Symbol: HSD17B6
• Synonyms: HSD17B6; hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse); hydroxysteroid (17 beta) dehydrogenase 6; 17-beta-hydroxysteroid dehydrogenase type 6; 3(alpha >beta) hydroxysteroid epimerasel; 3 hydroxysteroid epimerase; HSE; NAD+ dependent 3 alpha hydroxysteroid dehydrogenase; oxidative 3 alpha hydroxysteroid dehydrogenase; oxidoreductase; retinol dehydrogenase; RODH; SDR9C6; short chain dehydrogenase/reductase family 9C; member 6; 17-beta-HSD6; 17-beta-HSD 6; 3-alpha-> beta-HSE; 3-hydroxysteroid epimerase; beta-hydroxysteroid epimerase; 3(alpha-> beta)-hydroxysteroid epimerase; beta)-hydroxysteroid epimerasel; oxidative 3-alpha hydroxysteroid dehydrogenase; oxidative 3-alpha-hydroxysteroid-dehydrogenase; short chain dehydrogenase/reductase family 9C, member 6; NAD+ -dependent 3 alpha-hydroxysteroid dehydrogenase 3-hydroxysteroid epimerase
• Gene ID: 8630
• mRNA Refseq: NM_003725
• Protein Refseq: NP_003716
• MIM: 606623
• UniProt ID: O14756