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HSD17B7

  • Official Full Name

    hydroxysteroid (17-beta) dehydrogenase 7

  • Overview

    HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the;biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol;(Marijanovic et al., 2003 (PubMed 12829805)).
  • Synonyms

    HSD17B7; hydroxysteroid (17-beta) dehydrogenase 7; 3-keto-steroid reductase; PRAP; SDR37C1; short chain dehydrogenase/reductase family 37C; member 1; 17 beta HSD 7; 17 beta hydroxysteroid dehydrogenase 7; 17 beta hydroxysteroid dehydrogenase type VII; 17-beta-HSD 7; 17-beta-hydroxysteroid dehydrogenase 7; 17beta hydroxysteroid dehydrogenase; 3 keto steroid reductase; DHB7_HUMAN; Estradiol 17 beta dehydrogenase 7; Estradiol 17-beta-dehydrogenase 7; hydroxysteroid (17 beta) dehydrogenase 7; MGC12523; MGC75018; Short chain dehydrogenase/reductase family 37C member 1; 17 beta-hydroxysteroid dehydrogenase type VII; short chain dehydrogenase/reductase family 37C, member 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Zebrafish
  • E.coli expression system
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human HSD17B7-5074H Recombinant Human HSD17B7 Protein, GST-tagged Wheat Germ GST
Human HSD17B7-819HCL Recombinant Human HSD17B7 cell lysate N/A
Human HSD17B7-1470HFL Recombinant Full Length Human HSD17B7 Protein, C-Flag-tagged Mammalian cells Flag
Human HSD17B7-1108H-B Recombinant Human HSD17B7 Protein Pre-coupled Magnetic Beads HEK293
Human HSD17B7-2129H Recombinant Human HSD17B7 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human HSD17B7-3193H Recombinant Human HSD17B7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human HSD17B7-3873HF Recombinant Full Length Human HSD17B7 Protein, GST-tagged In Vitro Cell Free System GST 341 amino acids
Human HSD17B7-1108H Recombinant Human HSD17B7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse HSD17B7-7881M Recombinant Mouse HSD17B7 Protein Mammalian Cell His
Mouse HSD17B7-4338M Recombinant Mouse HSD17B7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Hsd17b7-1181M Recombinant Mouse Hsd17b7 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Mouse HSD17B7-4338M-B Recombinant Mouse HSD17B7 Protein Pre-coupled Magnetic Beads HEK293
Rat HSD17B7-2930R Recombinant Rat HSD17B7 Protein Mammalian Cell His
Rat HSD17B7-2585R-B Recombinant Rat HSD17B7 Protein Pre-coupled Magnetic Beads HEK293
Rat HSD17B7-2585R Recombinant Rat HSD17B7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey HSD17B7-602C Recombinant Cynomolgus HSD17B7 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey HSD17B7-348C-B Recombinant Cynomolgus Monkey HSD17B7 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey HSD17B7-348C Recombinant Cynomolgus Monkey HSD17B7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Homo sapiens (Human) RFL8642HF Recombinant Full Length Human 3-Keto-Steroid Reductase(Hsd17B7) Protein, His-Tagged E.coli expression system His Full Length (1-341)
Mus musculus (Mouse) RFL2090MF Recombinant Full Length Mouse 3-Keto-Steroid Reductase(Hsd17B7) Protein, His-Tagged E.coli expression system His Full Length (1-334)
Zebrafish HSD17B7-4686Z Recombinant Zebrafish HSD17B7 Mammalian Cell His
Chicken HSD17B7-4899C Recombinant Chicken HSD17B7 Mammalian Cell His
Chicken HSD17B7-4898C Recombinant Chicken HSD17B7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • HSD17B7 Related Articles

HSD17B7 involved in several pathways and played different roles in them. We selected most pathways HSD17B7 participated on our site, such as Steroid biosynthesis, Steroid hormone biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with HSD17B7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Steroid biosynthesisSOAT2;FAXDC2;EBP;HSD17B7;SC5DL;LSS;CYP51;MSMO1;Cel
Steroid hormone biosynthesisUGT1A1;HSD17B12;CYP2C55;CYP19A1A;SRD5A2B;COMTB;UGT1A4;HSD3B6;UGT5G1
Metabolic pathwaysSAT2B;UCK2;ASPA;AK7B;CMASA;MTMR6;ASL2;mt-Atp8;CYP2C38
Ovarian steroidogenesisHSD17B7;CYP2J6;BMP6;INS1;INS;HSD17B1;FSHR;GDF9;PRKACA

HSD17B7 has several biochemical functions, for example, 3-keto sterol reductase activity, estradiol 17-beta-dehydrogenase activity, prolactin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HSD17B7 itself. We selected most functions HSD17B7 had, and list some proteins which have the same functions with HSD17B7. You can find most of the proteins on our site.

Function Related Protein
3-keto sterol reductase activityDHRS4;CBR3;HSD17B7
estradiol 17-beta-dehydrogenase activityRDH8A;HSD17B2;HSD17B14;HSD17B12B;HSD17B1;HSD17B8;HSD17B10;HSD17B12;HSD17B7
prolactin receptor bindingHSD17B7;GH1;PRL4A1;PRL

HSD17B7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HSD17B7 here. Most of them are supplied by our site. Hope this information will be useful for your research of HSD17B7.

CA1; DTYMK; GORAB; AGPAT6; BRSK1

Seth, G; Ozturk, M; et al. Reverting cholesterol auxotrophy of NS0 cells by altering epigenetic gene silencing. BIOTECHNOLOGY AND BIOENGINEERING 93:820-827(2006).
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