Recombinant Full Length Human HSD17B7 Protein, C-Flag-tagged

• Cat.No.: HSD17B7-1470HFL
• Product Overview: Recombinant Full Length Human HSD17B7 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 38 kDa
• AA Sequence: MRKVVLITGASSGIGLALCKRLLAE DDELHLCLACRNMSKAEAVCAALLA SHPTAEVTIVQVDVSNLQSV FRASKELKQRFQRLDCIYLNAGIMP NPQLNIKALFFGLFSRKVIHMFSTA EGLLTQGDKITADGLQEVFE TNVFGHFILIRELEPLLCHSDNPSQ LIWTSSRSARKSNFSLEDFQHSKGK EPYSSSKYATDLLSVALNRN FNQQGLYSNVACPGTALTNLTYGIL PPFIWTLLMPAILLLRFFANAFTLT PYNGTEALVWLFHQKPESLN
  PLIKYLSATTGFGRNYIMTQKMDLD EDTAEKFYQKLLELEKHIRVTIQKT DNQARLSGSCLTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Druggable Genome
• Protein Pathways: Androgen and estrogen metabolism, Metabolic pathways, Steroid biosynthesis

Gene Information

• Gene Name: HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 [ Homo sapiens (human) ]
• Official Symbol: HSD17B7
• Synonyms: PRAP; SDR37C1
• Gene ID: 51478
• mRNA Refseq: NM_016371.4
• Protein Refseq: NP_057455.1
• MIM: 606756
• UniProt ID: P56937