htr1a
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  • Official Full Name
  • 5-hydroxytryptamine (serotonin) receptor 1A
  • Background
  • This gene encodes a G protein-coupled receptor for 5-hydroxytryptamine (serotonin), and belongs to the;5-hydroxytryptamine receptor subfamily. Serotonin has been implicated in a number of physiologic processes and;pathologic conditions. Inactivation of this gene in mice results in behavior consistent with an increased anxiety and;stress response. Mutation in the promoter of this gene has been associated with menstrual cycle-dependent periodic;fevers.
  • Synonyms
  • HTR1A; 5-hydroxytryptamine (serotonin) receptor 1A; 5-hydroxytryptamine receptor 1A; 5 HT1A receptor; 5 HT 1A; 5 HT receptor 1A; 5 HT1A; 5 hydroxytryptamine (serotonin) receptor 1A; 5 hydroxytryptamine receptor 1A; 5-HT-1A; 5-HT1A; 5HT 1A; 5HT 1A receptor; 5HT receptor 1A; 5HT1A_HUMAN; ADRB2RL1; ADRBRL1; G 21; G protein coupled receptor; G-21; Gpcr 18; Gpcr18; Guanine nucleotide binding regulatory protein-coupled receptor; Serotonin 1A receptor; Serotonin 5HT1A receptor; Serotonin receptor 1A; 5HT1A; RAT5HT1A
Cat.#:HTR1A-148HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human HTR1A
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Cat.#:HTR1A-25HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HTR1A protein
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Cat.#:HTR1A-26HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HTR1A protein, GST-tagged
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Cat.#:HTR1A-27HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human HTR1A protein, GST-tagged
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Cat.#:HTR1A-2959RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat HTR1A Protein
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Cat.#:HTR1A-2173RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey HTR1A Protein, His-tagged
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Cat.#:HTR1A-4048CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken HTR1A
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Cat.#:Kit-0995Tag:
Source (Host):Species:
Product nameTotal Collagen Assay Kit (Perchlorate-Free)
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Cat.#:Kit-1349Tag:
Source (Host):Species:
Product nameHTR1A CHO-K1 β-Arrestin GPCR Assay Kit
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Cat.#:CSC-RG0552Tag:
Source (Host):Species:Human
Product nameHuman HTR1A/Gi Stable Cell Line-CHO
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Cat.#:CSC-RG0383Tag:
Source (Host):Species:Human
Product nameHuman HTR1A-FLAG Stable Cell Line-HEK293T
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Cat.#:CSC-RG0750Tag:
Source (Host):Species:Human
Product nameHuman HTR1A/Galpha15 Stable Cell Line-Chem-3
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Cat.#:CSC-RG0778Tag:
Source (Host):Species:Human
Product nameHuman HTR1A Stable Cell Line-CHO
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Involved Pathway

HTR1A involved in several pathways and played different roles in them. We selected most pathways HTR1A participated on our site, such as cAMP signaling pathway, Neuroactive ligand-receptor interaction, Serotonergic synapse, which may be useful for your reference. Also, other proteins which involved in the same pathway with HTR1A were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
cAMP signaling pathway
MAP2K2; CAMK2A; PDE4B; PTGER3; CALM2; GLI3; PIK3CA; BRAF; GIPR; PIK3CB
Neuroactive ligand-receptor interaction
PRP2; GABRG3; GABRB2; LPAR4; P2RX3A; TAAR10B; TAAR8B; GRIA2B; GRIK3; LOC780933
Serotonergic synapse
CYP2C70; ITPR3; ALOX8; MAOA; ALOX5; PRKCA; CYP2D26; GNG7; TPH2; ARAF

Protein Function

HTR1A has several biochemical functions, for example, protein binding, serotonin receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by HTR1A itself. We selected most functions HTR1A had, and list some proteins which have the same functions with HTR1A. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein CTF1; SEPT3; UBOX5; ZBTB49; KIF9; TBX22; FAM96B; ATP2B1; RPL23A; MYO7B
Function serotonin receptor activity
Related Protein HTR7; HTR5AL; HTR1AA; HTR3E; HTR1F; HTR2C; HTR1B; HTR1E; HTR3B; HTR3A

HTR1A Related Articles

Matthews, PR; Harrison, PJ; et al. A morphometric, immunohistochemical, and in situ hybridization study of the dorsal raphe nucleus in major depression, bipolar disorder, schizophrenia, and suicide. JOURNAL OF AFFECTIVE DISORDERS 137:125-134(2012).
Xu, J; Zhang, GL; et al. Hypomethylation of the HTR1A promoter region and high expression of HTR1A in the peripheral blood lymphocytes of patients with systemic lupus erythematosus. LUPUS 20:678-689(2011).