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IBTK

  • Official Full Name

    inhibitor of Bruton agammaglobulinemia tyrosine kinase

  • Overview

    Brutons tyrosine kinase (Btk) is a member of the Btk/Tec family of cytoplasmic tyrosine kinases. Like other Btk family members, it contains a pleckstrin homology (PH) domain and Src homology SH3 and SH2 domains. Btk plays an important role in B cell devel
  • Synonyms

    IBTK; inhibitor of Bruton agammaglobulinemia tyrosine kinase; Bruton agammaglobulinemia tyrosine kinase inhibitor , BTKI; inhibitor of Bruton tyrosine kinase; DKFZP564B116; BTK-binding protein; inhibitor of Brutons tyrosine kinase; inhibitor of Brutons ty;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • HEK293
  • Mammalian Cell
  • Sf9 Insect Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human IBTK-1370H Active Recombinant Human BTK, His-tagged Sf9 Insect Cell His Full length
Human IBTK-5317HCL Recombinant Human IBTK 293 Cell Lysate HEK293 N/A
Mouse IBTK-7967M Recombinant Mouse IBTK Protein Mammalian Cell His
Mouse IBTK-4401M Recombinant Mouse IBTK Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse IBTK-4401M-B Recombinant Mouse IBTK Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey IBTK-608C Recombinant Cynomolgus IBTK Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey IBTK-354C-B Recombinant Cynomolgus Monkey IBTK Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey IBTK-354C Recombinant Cynomolgus Monkey IBTK Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • IBTK Related Articles

IBTK involved in several pathways and played different roles in them. We selected most pathways IBTK participated on our site, such as BCR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with IBTK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
BCR signaling pathwayPAG1;MAP4K1;CSNK2A1;MALT1;DOK1;CSK;POU2F2;NETO2;IBTK

IBTK has several biochemical functions, for example, protein kinase binding, protein tyrosine kinase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by IBTK itself. We selected most functions IBTK had, and list some proteins which have the same functions with IBTK. You can find most of the proteins on our site.

Function Related Protein
protein kinase bindingRAB8A;PIFO;TBL2;PARK2;CD36;GSK3B;SREBF1;CNTLN;MEF2A
protein tyrosine kinase inhibitor activityGNB2L1;IBTK;FGFR1OP

IBTK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with IBTK here. Most of them are supplied by our site. Hope this information will be useful for your research of IBTK.

BTK; CD2BP2; RGS2; SNRPN; EIF4A2; PPP1CA; hemC; LAMTOR3; POP7; MSL1; NOP56; SRP72; RPLP1; RPLP0; RPS3; Sars; RFC4; RFC1; RFC3

Spatuzza, C; Schiavone, M; et al. Physical and functional characterization of the genetic locus of IBtk, an inhibitor of Bruton's tyrosine kinase: evidence for three protein isoforms of IBtk. NUCLEIC ACIDS RESEARCH 36:4402-4416(2008).
  • Q&As
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