itpa
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  • Official Full Name
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
  • Synonyms
  • ITPA;inosine triphosphatase (nucleoside triphosphate pyrophosphatase);C20orf37;inosine triphosphate pyrophosphatase;dJ794I6.3;HLC14 06 P;NTPase;My049 protein;inosine triphosphatase-A;putative oncogene protein HLC14-06-P;nucleoside triphosphate diphosphatase;nucleoside-triphosphate diphosphatase;non-standard purine NTP pyrophosphatase;nucleoside-triphosphate pyrophosphatase;non-canonical purine NTP pyrophosphatase;inosine triphosphate pyrophosphohydrolase;ITPase;HLC14-06-P;
Cat.#:ITPA-4952HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ITPA Protein, GST-tagged
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Cat.#:ITPA-119HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human ITPA Protein, His-tagged
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Cat.#:ITPA-912HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ITPA Protein, His-tagged
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Cat.#:Itpa-7872MTag:His|GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Itpa protein, His & GST-tagged
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Cat.#:ITPA-3122RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ITPA Protein
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Cat.#:ITPA-4681CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ITPA
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Cat.#:ITPA-5798ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish ITPA
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Cat.#:ITPA-778HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ITPA, His-tagged
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Cat.#:ITPA-5113HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human ITPA 293 Cell Lysate
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Cat.#:Kit-0876Tag:N/A
Source (Host):Species:
Product nameContinuous ITP pyrophosphatase Assay Kit
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Involved Pathway

ITPA involved in several pathways and played different roles in them. We selected most pathways ITPA participated on our site, such as Drug metabolism - other enzymes, Metabolic pathways, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with ITPA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Drug metabolism - other enzymes
UGT1A6; Ces2c; CES1D; IMPDH1B; Ces2e; PNAT3; UGT1A6A; UGT1A6B; UCK2A; UGT1A7C
Metabolic pathways
POLE2; AK8; QARS; DEGS2; NDUFA12; G6PD; ATP6V0E1; NDUFS5; HMBSA; SPRA
Metabolism
INSIG2; ACY3; CA5B; ACSM1; PNPLA8; NDUFAF5; SCO1; AWAT1; SLC23A2; SLC44A5B
Metabolism of nucleotides
DUT; AK7; ADSS; NUDT15; DGUOK; TYMP; DCK; DPYD; AK8; DPYS
Purine metabolism
PDE1A; NUDT9; NT5C1AA; PRPS1; GUK1; POLR2J2; Adcy4; CANT1; POLA2; POLR2E
Pyrimidine metabolism
NME5; ENTPD6; NT5C1B-RDH14; CTPS2; DPYD; POLR2J; POLR2D; TXNRD2; CMPK2; RRM1

Protein Function

ITPA has several biochemical functions, for example, ITP diphosphatase activity, XTP diphosphatase activity, dITP diphosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ITPA itself. We selected most functions ITPA had, and list some proteins which have the same functions with ITPA. You can find most of the proteins on our site.
Function
Related Protein
Function ITP diphosphatase activity
Related Protein ITPA
Function XTP diphosphatase activity
Related Protein DOM3Z; ITPA; NUDT19
Function dITP diphosphatase activity
Related Protein DOM3Z; ITPA; NUDT16; NUDT19
Function metal ion binding
Related Protein CAPN8; VPS18; ZNF581; S100A10A; PHLPP1; SCRT2; TRIM35-23; NR2F6A; BTR12; ZNF354A
Function nucleotide binding
Related Protein DAZAP1; KIF20B; ADCY2B; EPHB3A; RBM42; MSI1; SRSF12; WRNIP1; STK26; RAD51L1

Interacting Protein

ITPA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ITPA here. Most of them are supplied by our site. Hope this information will be useful for your research of ITPA.
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