Recombinant Human ITPA Protein, His-tagged

• Cat.No.: ITPA-912H
• Product Overview: Recombinant Human ITPA(Met1-Ala194), transcript variant 1, fused with His tag at C-terminal was expressed in E. coli.

Specification

• Description: This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.
• Source: E. coli
• Tag: His
• Form: 20mM Tris-HCl, pH 8.0. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 22.5 kDa
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) [ Homo sapiens ]
• Official Symbol: ITPA
• Synonyms: ITPA; inosine triphosphatase (nucleoside triphosphate pyrophosphatase); C20orf37; inosine triphosphate pyrophosphatase; dJ794I6.3; HLC14 06 P; NTPase; My049 protein; inosine triphosphatase-A; putative oncogene protein HLC14-06-P; nucleoside triphosphate diphosphatase; nucleoside-triphosphate diphosphatase; non-standard purine NTP pyrophosphatase; nucleoside-triphosphate pyrophosphatase; non-canonical purine NTP pyrophosphatase; inosine triphosphate pyrophosphohydrolase; ITPase; HLC14-06-P
• Gene ID: 3704
• mRNA Refseq: NM_033453
• Protein Refseq: NP_258412
• MIM: 147520
• UniProt ID: Q9BY32