Recombinant Human ITPA Protein, His-tagged

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Recombinant Human ITPA Protein, His-tagged

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Cat.No. : ITPA-912H
Product Overview : Recombinant Human ITPA(Met1-Ala194), transcript variant 1, fused with His tag at C-terminal was expressed in E. coli.
Description : This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.
Source : E. coli
Tag : His
Form : 20mM Tris-HCl, pH 8.0. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Molecular Mass : 22.5 kDa
Endotoxin : < 0.1 EU per µg protein as determined by LAL test
Purity : >95% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) [ Homo sapiens ]
Official Symbol : ITPA
Synonyms : ITPA; inosine triphosphatase (nucleoside triphosphate pyrophosphatase); C20orf37; inosine triphosphate pyrophosphatase; dJ794I6.3; HLC14 06 P; NTPase; My049 protein; inosine triphosphatase-A; putative oncogene protein HLC14-06-P; nucleoside triphosphate diphosphatase; nucleoside-triphosphate diphosphatase; non-standard purine NTP pyrophosphatase; nucleoside-triphosphate pyrophosphatase; non-canonical purine NTP pyrophosphatase; inosine triphosphate pyrophosphohydrolase; ITPase; HLC14-06-P;
Gene ID : 3704
mRNA Refseq : NM_033453
Protein Refseq : NP_258412
MIM : 147520
UniProt ID : Q9BY32

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