Recombinant Mouse Itpa Protein, Myc/DDK-tagged

• Cat.No.: Itpa-3618M
• Product Overview: Purified recombinant protein of mouse full-length inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (Itpa), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Description: Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
• Source: HEK293T
• Species: Mouse
• Tag: Myc/DDK
• Molecular Mass: 21.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) [ Mus musculus (house mouse) ]
• Official Symbol: Itpa
• Synonyms: ITPA; inosine triphosphatase (nucleoside triphosphate pyrophosphatase); inosine triphosphate pyrophosphatase; ITPase; NTPase; nucleoside-triphosphate diphosphatase; non-standard purine NTP pyrophosphatase; nucleoside triphosphate pyrophosphatase; nucleoside-triphosphate pyrophosphatase; non-canonical purine NTP pyrophosphatase; Itp; AU020102; 2010016I08Rik
• Gene ID: 16434
• mRNA Refseq: NM_025922
• Protein Refseq: NP_080198
• UniProt ID: Q9D892