Ihh

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Ihh

Official Full Name indian hedgehog
Background This gene encodes a member of the hedgehog family of secreted signaling molecules. Hedgehog proteins are essential regulators of a variety of developmental processes including growth, patterning and morphogenesis. The encoded protein specifically plays a role in bone growth an differentiation. Mutations in this gene are the cause of brachydactyly type A1 which is characterized by shortening or malformation of the phalanges. Mutations in this gene are also the cause of acrocapitofemoral dysplasia. [provided by RefSeq, Feb 2010]
Synonyms IHH; indian hedgehog; BDA1; HHG2; indian hedgehog protein; HHG-2; Indian hedgehog homolog;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IHH-1673H Recombinant Human IHH protein, His & T7-tagged E.coli His/T7
    Human IHH-656H Recombinant Human IHH protein E.coli N/A
    Human IHH-7884H Recombinant Human IHH protein, His-tagged E.coli His
    Mouse Ihh-1892M Recombinant Mouse Indian Hedgehog E.coli N/A
    Chicken IHH-6516C Recombinant Chicken IHH Mammalian Cell His

    Ihh involved in several pathways and played different roles in them. We selected most pathways Ihh participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ihh were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Hedgehog signaling pathway GLI2; WNT11; SKI; GSK3AA; WNT2BB; ZIC2B; WNT8A; GLI2A; SKIA; WNT10B

    Ihh has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by Ihh itself. We selected most functions Ihh had, and list some proteins which have the same functions with Ihh. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding MYL12.1; PCDH2G16; RCVRN; LRP2; RASGRP2; OCM2; MYL7; MAN1A; DSC2L; ANXA11A
    patched binding CAV1; BBS1; CCNB1; IHH; SMO; DHH; PTCH1; SETD6; Shh
    peptidase activity GZMC; PLAUB; CELA3B; TMPRSS13B; CTSLL; AGA; PRSS42; ZMPSTE24; SHHB; TMPRSS11G

    Ihh has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ihh here. Most of them are supplied by our site. Hope this information will be useful for your research of Ihh.

    RHOD

    Kebenko, M; Drenckhan, A; et al. ErbB2 signaling activates the Hedgehog pathway via PI3K-Akt in human esophageal adenocarcinoma: Identification of novel targets for concerted therapy concepts. CELLULAR SIGNALLING 27:373-381(2015).
    Tillgren, V; Ho, JCS; et al. The Novel Small Leucine-rich Protein Chondroadherin-like (CHADL) Is Expressed in Cartilage and Modulates Chondrocyte Differentiation. JOURNAL OF BIOLOGICAL CHEMISTRY 290:918-925(2015).

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