KCNIP2

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KCNIP2

Official Full Name Kv channel interacting protein 2
Background This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.
Synonyms KCNIP2; Kv channel interacting protein 2; Kv channel-interacting protein 2; KCHIP2; potassium channel-interacting protein 2; A-type potassium channel modulatory protein 2; cardiac voltage-gated potassium channel modulatory subunit; MGC17241; DKFZp566L1246
    • Species :
    • Chicken
    • Human
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human KCNIP2-250H Recombinant Human KCNIP2, His-tagged E.coli His
    Human KCNIP2-5055HCL Recombinant Human KCNIP2 293 Cell Lysate HEK293 N/A
    Rat KCNIP2-3191R Recombinant Rat KCNIP2 Protein Mammalian Cell His
    Rhesus Macaque KCNIP2-2355R Recombinant Rhesus monkey KCNIP2 Protein, His-tagged Mammalian Cell His
    Chicken KCNIP2-5823C Recombinant Chicken KCNIP2 Mammalian Cell His

    KCNIP2 involved in several pathways and played different roles in them. We selected most pathways KCNIP2 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with KCNIP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    KCNIP2 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNIP2 itself. We selected most functions KCNIP2 had, and list some proteins which have the same functions with KCNIP2. You can find most of the proteins on our site.

    Function Related Protein
    contributes_to A-type (transient outward) potassium channel activity KCND3; KCNIP2
    A-type (transient outward) potassium channel activity KCNIP2; KCND2
    ER retention sequence binding KDELR2B; KDELR2A; KCNIP2; KIAA1199; KDELR3
    calcium ion binding MMP19; PNLIPRP1; FBN2; CIB1; RPH3A; MMP14A; PCDH1A6; CLEC3B; PCDH2AB9; EGFL7
    identical protein binding GYPA; TNN; NFKB1; NQO1; ALK; CLDN4; KCTD13; TTR; C1QTNF6; PRPS2
    ion channel binding HOMER1; PACS1; HSP90AB1; ID2; PDE4B; SCN3B; KCNH5; HTT; NOS1; PKD1
    potassium channel regulator activity KCNE2; KCNAB3; KCNMB2; KCNIP1; ARPP19; SGK2B; ABCC9; ADRB2; SGK2A; PIAS3
    protein N-terminus binding MNAT1; RPS21; NTSR1; MAP2K1; PEX14; RASSF1; RBPJ; SMARCA4; PDLIM5; TBL1XR1
    protein binding ZBTB7B; NAPG; PTK2; PTPN12; NEU2; ASAP3; SATB1; MALSU1; GCC1; ZNF664-FAM101A

    KCNIP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNIP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNIP2.

    KCND2; KCNIP4

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