kcnip2
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  • Official Full Name
  • Kv channel interacting protein 2
  • Background
  • This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.
  • Synonyms
  • KCNIP2; Kv channel interacting protein 2; Kv channel-interacting protein 2; KCHIP2; potassium channel-interacting protein 2; A-type potassium channel modulatory protein 2; cardiac voltage-gated potassium channel modulatory subunit; MGC17241; DKFZp566L1246
Cat.#:KCNIP2-250HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KCNIP2, His-tagged
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Cat.#:KCNIP2-3191RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat KCNIP2 Protein
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Cat.#:KCNIP2-2355RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey KCNIP2 Protein, His-tagged
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Cat.#:KCNIP2-5823CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken KCNIP2
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Cat.#:KCNIP2-5055HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human KCNIP2 293 Cell Lysate
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Protein Function

KCNIP2 has several biochemical functions, for example, contributes_to A-type (transient outward) potassium channel activity, A-type (transient outward) potassium channel activity, ER retention sequence binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNIP2 itself. We selected most functions KCNIP2 had, and list some proteins which have the same functions with KCNIP2. You can find most of the proteins on our site.
Function
Related Protein
Function contributes_to A-type (transient outward) potassium channel activity
Related Protein KCNIP2; KCND3
Function A-type (transient outward) potassium channel activity
Related Protein KCND2; KCNIP2
Function ER retention sequence binding
Related Protein KCNIP2; KDELR3; KDELR2B; KDELR2A; KIAA1199
Function calcium ion binding
Related Protein THBS4B; PCDHA2; PCDHGA12; PCLO; ANXA1B; PKD2L2; LDLRA; SYTL1; CDH11; GRM7
Function identical protein binding
Related Protein MTSS1; AHCY; SERPINA1; ETNPPL; UGP2; TRIM8; NQO1; TNN; SMN2; P2RX2
Function ion channel binding
Related Protein SRC; KCNE1L; DLG1; KCNQ1; KCNQ3; CALM1; PIRT; PDE4B; KCNB1; CALM3
Function potassium channel regulator activity
Related Protein KCNMB4; PIAS3; SGK2; KCNIP1; ABCC9; SUMO1; KCNE3; KCNE2; DPP6; KCNIP4
Function protein N-terminus binding
Related Protein SCFD1; PEX5; VPS25; THAP7; LACRT; SERPINB1A; KCNQ2; GTF2H2; EIF5A; TRAF6
Function protein binding
Related Protein HEMGN; STXBP3A; LSM10; CA; SRPK2; IL10RA; BATF; USF1; TMEM59; FAM207A

Interacting Protein

KCNIP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNIP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNIP2.
KCND2; KCNIP4