kcnip2
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  • Official Full Name
  • Kv channel interacting protein 2
  • Background
  • This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene.
  • Synonyms
  • KCNIP2; Kv channel interacting protein 2; Kv channel-interacting protein 2; KCHIP2; potassium channel-interacting protein 2; A-type potassium channel modulatory protein 2; cardiac voltage-gated potassium channel modulatory subunit; MGC17241; DKFZp566L1246
Cat.#:KCNIP2-250HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KCNIP2, His-tagged
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Cat.#:KCNIP2-3191RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat KCNIP2 Protein
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Cat.#:KCNIP2-2355RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey KCNIP2 Protein, His-tagged
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Cat.#:KCNIP2-5823CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken KCNIP2
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Cat.#:KCNIP2-5055HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human KCNIP2 293 Cell Lysate
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Protein Function

KCNIP2 has several biochemical functions, for example, contributes_to A-type (transient outward) potassium channel activity, A-type (transient outward) potassium channel activity, ER retention sequence binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KCNIP2 itself. We selected most functions KCNIP2 had, and list some proteins which have the same functions with KCNIP2. You can find most of the proteins on our site.
Function
Related Protein
Function contributes_to A-type (transient outward) potassium channel activity
Related Protein KCNIP2; KCND3
Function A-type (transient outward) potassium channel activity
Related Protein KCNIP2; KCND2
Function ER retention sequence binding
Related Protein KDELR3; KIAA1199; KDELR2A; KDELR2B; KCNIP2
Function calcium ion binding
Related Protein PCDH10B; THBS3A; S100A16; SLC24A1; PCDH1G3; PLA2G12A; HSP90B1; CBL; PCDH17; MYL5
Function identical protein binding
Related Protein MAP3K13; GSTM3; HSPB8; SNX8; APLP2; MCM6; PFKFB1; GOT2; PYDC3; SMN1
Function ion channel binding
Related Protein KCNIP2; HTT; TCAP; PPP1R9B; SCN5A; FKBP1B; CALM1; RYR2; ACTN2; TRPC1
Function potassium channel regulator activity
Related Protein KCNAB3; KCNMB1; KCNMB4; SGK2A; ADRB2; DRD2; CHP; ANK2; KCNAB2; SGK2B
Function protein N-terminus binding
Related Protein RELA; RPA2; RASSF1; TBL1XR1; DCTN4; CHMP6; ERCC5; STXBP1; NBN; KCNIP2
Function protein binding
Related Protein GTPBP4; CNTNAP4; CREB5; RGS6; PSMC4; FFAR2; DCTN2; CTAG1A; LRRC4B; CTNNA1

Interacting Protein

KCNIP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KCNIP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of KCNIP2.
KCND2; KCNIP4