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KIR2DS2

  • Official Full Name

    killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2

  • Overview

    KIR2D members of the killer cell immunoglobulin (Ig) like receptor (KIR) family, CD158a (KIR2DL1 and KIR2DS1), CD158b (KIR2DS2) and P50.3 are cell surface glycoproteins with two Ig domains, which are expressed on natural killer cells and some T cells.
  • Synonyms

    KIR2DL+KIR2DS1+KIR2DS2; killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2; KIR2DS2; killer cell immunoglobulin-like receptor 2DS2; 183ActI; CD158J; cl 49; nkat5; NKAT-5; p58 KIR; 1060P11.9.2; NK receptor 183 ActI; p58 NK receptor CL-49; MHC class I;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Homo sapiens (Human)
  • Human
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cells
  • Mammalian cells
  • C
  • His
  • Fc
  • Flag
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KIR2DS2-8191H Recombinant Human KIR2DS2 protein, His & GST-tagged E.coli His/GST His22~Ala304
Human KIR2DS2-364HCL Recombinant Human KIR2DS2 lysate HEK293 N/A
Human KIR2DS2-553H Recombinant Human KIR2DS2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human KIR2DS2-002H Recombinant Human KIR2DS2 Protein, C-His-tagged E.coli C-His
Human KIR2DS2-151H Recombinant Human KIR2DS2 Protein, His-tagged Human Cells His
Human KIR2DS2-6466H Recombinant Human KIR2DS2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human KIR2DS2-111H Recombinant Human KIR2DS2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human KIR2DS2-1497HFL Recombinant Full Length Human KIR2DS2 Protein, C-Flag-tagged Mammalian cells Flag
Human KIR2DS2-06H Recombinant Human KIR2DS2 Protein, Fc-tagged Mammalian cells Fc Met1-His245
Human KIR2DS2-111H-B Recombinant Human KIR2DS2 Protein Pre-coupled Magnetic Beads HEK293
Human KIR2DS2-0908H Recombinant Human KIR2DS2 Protein (His22-Glu291), N-GST tagged E.coli N-GST His22-Glu291
Homo sapiens (Human) RFL5330HF Recombinant Full Length Human Killer Cell Immunoglobulin-Like Receptor 2Ds2(Kir2Ds2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (22-304)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • KIR2DS2 Related Articles

KIR2DS2 involved in several pathways and played different roles in them. We selected most pathways KIR2DS2 participated on our site, such as Adaptive Immune System, Antigen processing and presentation, DAP12 interactions, which may be useful for your reference. Also, other proteins which involved in the same pathway with KIR2DS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Adaptive Immune SystemCD300LG;UBE2U;CXADR;Siglece;LILRB4;KLC3;RAET1E;TRIM11;ASB6
Antigen processing and presentationKLRC3;TAP2;NFYC;CTSB;Ctsl;HLA-G;RFXANK;HLA-DRB4;HSP90AA1
DAP12 interactionsFGF8B;DUSP6;NRG3;CLEC5A;PHB;SPRED3;ADRBK1;GRAP2A;JAK3
Immune SystemTXNIP;CFHL3;Mill2;PPAPDC1A;CASP4;PLD4;KIF3B;TRIM41;PIK3AP1
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cellCD200R4;CLEC2H;AF251705;KIR2DS2;TREML1;OSCAR;CD226;AMICA1;SIGLEC10
Innate Immune SystemTNRC5;MASP2;TNIP2;NLRP4B;TREX1;FAM49BA;BTR30;WIPF3;C1rb
Natural killer cell mediated cytotoxicityRAC3;FCGR4;NCR1;H60a;KRAS;MAP2K2;PLCG1;PPP3CB;HLA-C

KIR2DS2 has several biochemical functions, for example, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KIR2DS2 itself. We selected most functions KIR2DS2 had, and list some proteins which have the same functions with KIR2DS2. You can find most of the proteins on our site.

Function Related Protein
transmembrane signaling receptor activityKIR2DL4;CD3D;OR115-6;CD79B;OR4D6;GPR133;LEPR;ERBB2;GHRHRA

KIR2DS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KIR2DS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of KIR2DS2.

Ordonez, D; Gomez-Lozano, N; et al. Molecular characterisation of KIR2DS2(star)005, a fusion gene associated with a shortened KIR haplotype. GENES AND IMMUNITY 12:544-551(2011).
David, G; Morvan, M; et al. Discrimination between the main activating and inhibitory killer cell immunoglobulin-like receptor positive natural killer cell subsets using newly characterized monoclonal antibodies. IMMUNOLOGY 128:172-184(2009).
Toloza, SMA; Pellett, FJ; et al. Association of killer cell immunoglobulin-like receptor genotypes with vascular arterial events and anticardiolipin antibodies in patients with lupus. LUPUS 17:793-798(2008).
Lafarge, X; Pitard, V; et al. Expression of MHC class receptors confers functional intraclonal heterogeneity to a reactive expansion of gamma delta T cells. EUROPEAN JOURNAL OF IMMUNOLOGY 35:1896-1905(2005).
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