klf1
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  • Official Full Name
  • Kruppel-like factor 1 (erythroid)
  • Background
  • This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.
  • Synonyms
  • KLF1; Kruppel-like factor 1 (erythroid); Krueppel-like factor 1; EKLF; erythroid Kruppel like factor; monoclonal A3D8; erythroid Kruppel-like factor; erythroid krueppel-like transcription factor; erythroid-specific transcription factor EKLF; INLU; HBFQT
Cat.#:KLF1-394HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KLF1, GST-tagged
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Cat.#:KLF1-2411RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey KLF1 Protein, His-tagged
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Cat.#:KLF1-8577ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish KLF1
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Protein Function

KLF1 has several biochemical functions, for example, core promoter proximal region sequence-specific DNA binding, metal ion binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by KLF1 itself. We selected most functions KLF1 had, and list some proteins which have the same functions with KLF1. You can find most of the proteins on our site.
Function
Related Protein
Function core promoter proximal region sequence-specific DNA binding
Related Protein KLF4; PAX2; DMRTC1C2; DMRT1; DMRT2; DMRTA2; KLF1; TFAP2A; CXXC1; MEF2C
Function metal ion binding
Related Protein ZNF530; ZBTB2; ZSCAN4C; NUBP2; CYP4F14; HENMT1; CIT; HIVEP2; ZDHHC5A; SMPD4
Function transcription factor activity, sequence-specific DNA binding
Related Protein CREB5; CSRNP1; PAX7; HEYL; RBPJL; HNF4G; ZNF45; NKX2-8; NFE2L1; ZNF35
Function transcription regulatory region DNA binding
Related Protein EGR2; MEF2C; ZBTB14; GLI1; ERBB4; NR1D1; TP53; GABPA; BCL11AB; BCOR

Interacting Protein

KLF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLF1.
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