|Official Full Name||kallikrein-related peptidase 4|
|Background||Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Alternate splice variants for this gene have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]|
|Synonyms||KLK4; kallikrein-related peptidase 4; ARM1; EMSP; PSTS; AI2A1; EMSP1; KLK-L1; PRSS17; kallikrein; kallikrein-4; prostase; serine protease 17; kallikrein-like protein 1; androgen-regulated message 1; enamel matrix serine protease 1; enamel matrix serine proteinase 1; ESMP1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
KLK4 involved in several pathways and played different roles in them. We selected most pathways KLK4 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with KLK4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
KLK4 has several biochemical functions, for example, metal ion binding, protein binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLK4 itself. We selected most functions KLK4 had, and list some proteins which have the same functions with KLK4. You can find most of the proteins on our site.
|metal ion binding||KLF7B; ITGB1BP3; WBSCR17; CYP2AD2; EGR2; ZNF544; ZMYM2; TRIM2A; GALNT9; ZFP410|
|protein binding||NTSR1; AGAP2; COPRS; FOSL2; PSMA6; SDC2; AHCYL1; Fzd4; CNOT2; BIRC7|
|serine-type endopeptidase activity||TPP2; PRSS50; RHBDD2; DPP4; PRSS48; PRSS52; F9A; KLK1; GM5077; Gzmg|
|serine-type peptidase activity||KLK1B1; TMPRSS4A; PRSS59.2; KLK1B9; TMPRSS13A; PRSS52; GZMK; KLK7; TMPRSS13B; KLK1B26|
KLK4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLK4 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLK4.