KLK6
-
Official Full Name
kallikrein-related peptidase 6
-
Overview
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimers disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] -
Synonyms
KLK6; kallikrein-related peptidase 6; hK6; Bssp; Klk7; SP59; PRSS9; PRSS18; kallikrein-6; zyme; neurosin; protease M; serine protease 9; serine protease 18;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Human Cell
- In Vitro Cell Free System
- Mammalian Cell
- Mammalian cells
- Wheat Germ
- C
- His
- GST
- His (Fc)
- Avi
- His|GST
- Myc
- DDK
- Myc|DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- KLK6 Related Articles
- KLK6 Related Research Area
KLK6 involved in several pathways and played different roles in them. We selected most pathways KLK6 participated on our site, such as Alpha-synuclein signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLK6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Alpha-synuclein signaling | FKBP1A;BLK;KLK6;TOR1A;CSNK2A1;PARK7;STUB1 |
KLK6 has several biochemical functions, for example, protein binding, serine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLK6 itself. We selected most functions KLK6 had, and list some proteins which have the same functions with KLK6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | MRPL15;RTN4RL1B;NR1D2;PAQR5;ATF6B;USHBP1;PPP6R3;PTPN4;NAT8 |
| serine-type endopeptidase activity | FURIN;F7;Prss32;KLK4;PIK3IP1;PROCA;KLK12;IMMP1L;C1RL |
KLK6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLK6 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLK6.
pheserargamc; COL1A1; COL4A1; COL1A2; FGA; FGB; APP; COL4A2; COL4A5; CSN1S1; COL4A4; COL4A3; COL4A6
- Q&As
- Reviews
Q&As (6)
Ask a questionStudies have shown that Klk6 recombinant protein may be involved in the occurrence and progression of tumors, especially in pancreatic and gastric cancers.
The level of Klk6 recombinant protein in pregnant women may change due to the needs of fetal growth and development, and regular monitoring is required.
The current treatments for Klk6 recombinant protein mainly include gene therapy, protein replacement therapy, and drug therapy for trypsin activity.
Studies have shown that Klk6 recombinant protein may be associated with cardiovascular diseases, liver diseases, and lung diseases.
Klk6 recombinant protein is mainly involved in the digestive process in the human body, helping to break down proteins in food.
If the level of Klk6 recombinant protein is abnormal, the treatment may include the use of drugs or other special treatments, depending on the condition and the doctor's recommendation.
Customer Reviews (3)
Write a reviewWhen experimenting with the KLK6, clear and consistent results are available for easy data analysis and interpretation.
KLKKLK6 products are available in a wide range of specifications for experimental designs of different sizes and needs.
KLK6 has a long half-life and is able to maintain stability and reliability during experiments.
Ask a Question for All KLK6 Products
Required fields are marked with *
My Review for All KLK6 Products
Required fields are marked with *
