• Official Full Name
  • keratin 4
  • Background
  • The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
  • Synonyms
  • KRT4; keratin 4; CYK4; keratin, type II cytoskeletal 4; CK4; cytokeratin 4; K4; keratin; type II cytoskeletal 4; type-II keratin Kb4; CK-4; FLJ31692
Source (Host):YeastSpecies:Human
Product nameRecombinant Human KRT4 Protein (1-534 aa), His-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KRT4 Protein (1-534 aa), His-SUMO-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human KRT4 protein, His-tagged
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human KRT4 protein, GST-tagged
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human KRT4 protein, GST-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse KRT4 Protein
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Krt4 protein, His & S-tagged
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat KRT4 Protein
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish KRT4
Source (Host):Species:Human
Product nameRecombinant Human KRT4 cell lysate

Protein Function

KRT4 has several biochemical functions, for example, protein binding, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KRT4 itself. We selected most functions KRT4 had, and list some proteins which have the same functions with KRT4. You can find most of the proteins on our site.
Related Protein
Function protein binding
Related Protein ALCAM; GAGE8; MYO5B; C2orf88; PTPN18; INHA; NFYB; CAMK2B; PRC1; PEX11G
Function structural molecule activity
Related Protein VIML; KRT6C; CLDN10A; LAMA5; DESMA; MPZL1; CLDN15B; MAPK8IP2; COL18A1; KRT84

Interacting Protein

KRT4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KRT4 here. Most of them are supplied by our site. Hope this information will be useful for your research of KRT4.
KRT13; KRT38; tax; KRT15; KRT33B; KRT40; USP1; UCHL1

KRT4 Related Articles

Sawanobori, Y; Ueta, H; et al. Three Distinct Subsets of Thymic Epithelial Cells in Rats and Mice Defined by Novel Antibodies. PLOS ONE 9:-(2014).
Nayak, AP; Hettick, JM; et al. Toluene Diisocyanate (TDI) Disposition and Co-Localization of Immune Cells in Hair Follicles. TOXICOLOGICAL SCIENCES 140:327-337(2014).