lair1
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  • Official Full Name
  • leukocyte-associated immunoglobulin-like receptor 1
  • Background
  • The protein encoded by this gene is an inhibitory receptor found on peripheral mononuclear cells, including NK cells, T cells, and B cells. Inhibitory receptors regulate the immune response to prevent lysis of cells recognized as self. The gene is a member of both the immunoglobulin superfamily and the leukocyte-associated inhibitory receptor family. The gene maps to a region of 19q13.4 called the leukocyte receptor cluster, which contains at least 29 genes encoding leukocyte-expressed receptors of the immunoglobulin superfamily.
  • Synonyms
  • LAIR1; leukocyte-associated immunoglobulin-like receptor 1; leukocyte associated Ig like receptor 1; CD305; 5133400O11Rik; D7Bwg0421e; hLAIR1; LAIR 1; LAIR-1; LAIR1 protein; LAIR1_HUMAN; Leukocyte associated immunoglobulin like receptor 1; OTTHUMP00000068183; OTTHUMP00000068184; OTTHUMP00000068185; OTTHUMP00000068186; OTTHUMP00000068187; leukocyte-associated Ig-like receptor 1
Cat.#:LAIR1-1706RTag:mIgG2a
Source (Host):HEK293Species:Rhesus Monkey
Product nameRecombinant Rhesus Monkey LAIR1 Protein, mIgG2a-tagged
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Cat.#:LAIR1-523HTag:His|Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human LAIR1 Protein, His-Avi-tagged, Biotinylated
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Cat.#:LAIR1-166HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human LAIR1 Protein, MYC/DDK-tagged
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Cat.#:LAIR1-377HTag:human|IgG1|Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human LAIR1 protein, Fc-tagged
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Cat.#:LAIR1-378MTag:Mouse|IgG2a|Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse LAIR1 protein, Mouse IgG2a Fc-tagged, low endotoxin
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Cat.#:LAIR1-382HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human LAIR1 protein, His-tagged
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Cat.#:LAIR1-29001THTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LAIR1
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Cat.#:LAIR1-524HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human LAIR1 Protein, His-tagged
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Cat.#:LAIR1-525HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human LAIR1 protein, Fc-tagged
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Cat.#:LAIR1-624HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human LAIR1
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Cat.#:Lair1-33MTag:His
Source (Host):Insect cellsSpecies:Mouse
Product nameRecombinant Mouse Lair1 protein, His-tagged
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Cat.#:Lair1-6972MTag:His
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Lair1, His tagged
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Cat.#:Lair1-6973MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse Lair1 protein, Fc-tagged
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Cat.#:LAIR1-3345RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat LAIR1 Protein
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Cat.#:LAIR1-1703RTag:N/A
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey LAIR1 Protein
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Cat.#:LAIR1-1704RTag:hIgG1
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey LAIR1 Protein, hIgG1-tagged
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Cat.#:LAIR1-1705RTag:hIgG4
Source (Host):HEK293Species:Rhesus monkey
Product nameRecombinant Rhesus Monkey LAIR1 Protein, hIgG4-tagged
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Cat.#:LAIR1-350HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Leukocyte-associated Immunoglobulin-like Receptor 1
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Cat.#:LAIR1-348HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Leukocyte-associated Immunoglobulin-like Receptor 1, His-tagged
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Cat.#:LAIR1-1331MCLTag:N/A
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse LAIR1 cell lysate
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Involved Pathway

LAIR1 involved in several pathways and played different roles in them. We selected most pathways LAIR1 participated on our site, such as Adaptive Immune System, Immune System, Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with LAIR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
Mill2; SIGLEC8; CDKN1B; HECTD3; HCST; AMICA1; HLA-DQB2; AP1B1; KIF2B; CYBB
Immune System
TRIM68; SIGLEC5; BTR18; CR1; RNF182; DEFB4A; TRIM11; GBP2; CTSC; SIGLEC15
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
ICAM4; CD200R1; KLRB1A; Mill2; CD300A; CD300LB; CRTAM; CLEC2D; LILRA1; LILRA2

Protein Function

LAIR1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LAIR1 itself. We selected most functions LAIR1 had, and list some proteins which have the same functions with LAIR1. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein TRPV5; TRMT2B; GPS2; TMEM25; PDCD10; DCTN3; LPA; FDXR; DEPDC1; FAM111A

Interacting Protein

LAIR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LAIR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of LAIR1.
PTPN6; CSK